Results 121 to 130 of about 1,104,681 (217)

Real-World Data on the Efficacy and Safety of Osilodrostat in Patients with Cushing's Disease in Spain. [PDF]

J Clin Med
Araujo-Castro M, García-Centeno R, González L, Hanzu FA, Orois A, Camara R, García MDO, Echarri AI, Gracia Gimeno P, Pascual-Corrales E, Biagetti B, Cardona A, González Molero I, Simo-Servat A, Guerrero Pérez F, Villar-Taibo R, Bernabéu I, Fajardo-Montañana C, Novo-Rodríguez C, Tenorio Jimenéz C, Calatayud M, Moure Rodríguez MD, Cordido F, Castro A, Valero LM, Paja Fano M, Goi J, Aulinas A, Abellán P, Iglesias P, Soto-Moreno A.   +30 more
europepmc   +1 more source

Advancing regulatory science through real-world data and real-world evidence

Journal of Clinical and Translational Science
Pablo Cure, Joshua P. Fessel, Christopher M. Hartshorn, Scott J. Steele   +3 more
openaire   +3 more sources

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

FEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold, Janik Riese, Lancelot Seillier, Mark Kühnel, Julia Pannhausen, Charlotte O. J. Fröhlich, Christian Martin, Peter Boor, Matthias Saar, Danny D. Jonigk, Nadine T. Gaisa, Michael Rose   +11 more
wiley   +1 more source

Pharmacogenomics-guided personalized medicine in a clinical setting: real-world data. [PDF]

Pharmacogenet Genomics
Liang J, Brand L, Ruiter R, Smit PW, Vos CNF, van der Vlugt JJB, Aarab I, Swen JJ, Krens LL, Bosch TM.   +9 more
europepmc   +1 more source

Understanding bio‐based polymers: A study of origins, properties, biodegradation and their impact on health and the environment

FEBS Open Bio, EarlyView.
This review provides an overview of bio‐based polymer sources, their unique functional properties and their environmental impact, and addresses their role as sustainable alternatives. It discusses end‐of‐life options, including composting and anaerobic digestion for renewable energy.
Sabina Kolbl Repinc, Blaž Stres, Mirica Karlovits, Igor Karlovits, Petra Jerič, Ondrej Panák, Anja Verbič, Blaž Likozar, Uroš Novak   +8 more
wiley   +1 more source

Real-world data on the abuse potential of medications for the treatment of insomnia: a disproportionality analysis of the FAERS database. [PDF]

Front Pharmacol
Saskin P, McCall WV, Neubauer DN, Crucitti A, Perry B, Luyet PP, Jaziri R, Vaillant C.   +7 more
europepmc   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source

Mavacamten in the Treatment of Obstructive Hypertrophic Cardiomyopathy: from Pathophysiology To Real World Data. [PDF]

Curr Cardiol Rep
Panichella G, Garofalo M, Ragagnin M, Fanizzi AI, Zampieri M, Del Franco A, Cappelli F, Pieroni M, Olivotto I.   +8 more
europepmc   +1 more source

Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

FEBS Open Bio, EarlyView.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi, Zainab Quraishi, Shima Khezri Azizi Far, Madaleine Ward, Aidan Conway, Reem Abdulredha, Eman Mshari, Yousif A. Shamsaldeen   +7 more
wiley   +1 more source

Food safety regulations and surveillance in Bangkok, Thailand - with 5-year real world data. [PDF]

Trop Dis Travel Med Vaccines
Techavachara N, Veeramanomai T, Piyaphanee W, Chen LH.   +3 more
europepmc   +1 more source