Results 161 to 170 of about 2,671,764 (310)

“Real-World Evidence?”

JACC: Cardiovascular Interventions, 2016
openaire   +3 more sources

Editorial: Real-world data and real-world evidence in hematologic malignancies

Frontiers in Oncology, 2023
Malagola, Michele, Ohgami, Robert, Greco, Raffaella   +2 more
openaire   +4 more sources

Biliary Tract Carcinoma: Real-World Evidence in a Developing Country. [PDF]

Cureus
Lema M, Lema C, Preciado B, Hoyos Duque S, Luján M, Aguirre D, Bonilla C, Gómez D, Pérez E, Pineda M, Patiño S.   +10 more
europepmc   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Temozolomide reconsidered: Real-World evidence in resistant melanoma cases. [PDF]

Oncologist
Maselli-Schoueri JH, Martinez E, Lagos E, Campos EF, Saldanha EF, Muniz TP, Butler MO, Saibil SD.   +7 more
europepmc   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Pharmacoepidemiology in the Era of Real-World Evidence [PDF]

Current Epidemiology Reports, 2017
openaire   +2 more sources

Antithrombotic Therapy After Intracerebral Hemorrhage: Real-World Evidence for In-Hospital Resumption. [PDF]

CNS Neurosci Ther
Li S, Qu T, Zhou X, Miao Q, Ni J, Peng B.   +5 more
europepmc   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Editorial: Utilizing real-world evidence for better endocrine health management. [PDF]

Front Endocrinol (Lausanne)
Mei M, Lopes LC, Li C.
europepmc   +1 more source