Results 171 to 180 of about 1,338,680 (315)

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

FEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda, Satoru Sugimoto, Chiharu Cho, Madoka Konishi, Nozomi Inoue, Satoshi Miyagaki, Yasuhiro Kawabe, Takuro Okamura, Masahide Hamaguchi, Hisakazu Nakajima, Michiaki Fukui, Masakazu Shinohara, Tomoko Iehara   +12 more
wiley   +1 more source

Antithrombotic Therapy After Intracerebral Hemorrhage: Real-World Evidence for In-Hospital Resumption. [PDF]

CNS Neurosci Ther
Li S, Qu T, Zhou X, Miao Q, Ni J, Peng B.   +5 more
europepmc   +1 more source

Introduction to real-world evidence studies

Perspectives in Clinical Research, 2021
openaire   +4 more sources

Real‐World Evidence and the Regulation of Medicines [PDF]

Clinical Pharmacology & Therapeutics, 2021
openaire   +2 more sources

Editorial: Real-world data and real-world evidence in hematologic malignancies

Frontiers in Oncology, 2023
Malagola, Michele, Ohgami, Robert, Greco, Raffaella   +2 more
openaire   +4 more sources

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Editorial: Utilizing real-world evidence for better endocrine health management. [PDF]

Front Endocrinol (Lausanne)
Mei M, Lopes LC, Li C.
europepmc   +1 more source

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

FEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman, Katarzyna Stapor, Leszek Konieczny, Krzysztof Gądek, Piotr Nowakowski   +4 more
wiley   +1 more source

Real-World Evidence for Drug Value Assessment in China: Learning from International Experiences. [PDF]

Drugs Real World Outcomes
Hartzema AG, Gehchan A, Guo JD, Xuan J.
europepmc   +1 more source

World Real Interest Rates: A Global Savings and Investment Perspective [PDF]

Over the past 15 years, long-term interest rates have declined to levels not seen since the 1970s. This paper explores possible shifts in global savings and investment that have led to this fall in the world real interest rate.
Michael Francis, Brigitte Desroches
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