Results 91 to 100 of about 19,661,854 (307)

NAPRT loss promotes lung tumor initiation and growth through AKT signaling independently of NAD+ biosynthesis

open access: yesMolecular Oncology, EarlyView.
Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh   +11 more
wiley   +1 more source

Virus culture and real-time RT-PCR in identifying influenza viruses from influenza-like illness cases in Indonesia 2007-2008

open access: yesHealth Science Journal of Indonesia, 2012
Latar belakang: Adanya perbedaan hasil antara kultur virus dengan real-time polymerase chain reaction (RT-PCR) yang digunakan dalam surveilans influenza-like illness (ILI) menunjukkan perlunya mengevaluasi hasil kultur virus yang didapatkan dengan hasil ...
Irene L. Indalao   +3 more
doaj   +3 more sources

Primers for real-time quantitative RT-PCR.

open access: yes, 2022
Primers were designed using Primer-BLAST or according to previous reports[24,62]. 24. Sengiku, A.; Ueda, M.; Kono, J.; Sano, T.; Nishikawa, N.; Kunisue, S.; Tsujihana, K.; Liou, L.S.; Kanematsu, A.; Shimba, S., et al. Circadian coordination of ATP release in the urothelium via connexin43 hemichannels. Sci Rep 2018, 8, 1996, doi:10.1038/s41598-018-20379-
openaire   +2 more sources

Primer sequences for RT-PCR and Real-time PCR.

open access: yes, 2013
Primer sequences for RT-PCR and Real-time PCR.
Hyeon-Ji Kang (404230)   +6 more
core   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

open access: yesMolecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico   +5 more
wiley   +1 more source

Primers for quantitative real time PCR and RT-PCR.

open access: yes, 2014
Primers for quantitative real time PCR and RT-PCR.
Junye Shen (670568)   +9 more
core   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

open access: yesMolecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault   +12 more
wiley   +1 more source

Q-Gene: processing quantitative real-time RT–PCR data [PDF]

open access: yesBioinformatics, 2003
Abstract Summary: Q-Gene is an application for the processing of quantitative real-time RT–PCR data. It offers the user the possibility to freely choose between two principally different procedures to calculate normalized gene expressions as either means of Normalized Expressions or Mean Normalized Expressions.
openaire   +3 more sources

Primers used in conventional PCR and Real-time RT-PCR.

open access: yes, 2017
Primers used in conventional PCR and Real-time RT-PCR.
Ke Rao (3684574)   +8 more
core   +1 more source

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