Results 131 to 140 of about 2,499,352 (307)

Social reasoning of early adolescents and parents regarding parent–child conflicts

open access: yesThe Japanese journal of psychology, 2015
Few researches have delineated how adolescents and parents view conflict in familial settings in Japan. Seventh and eighth grade junior high school students (n = 63) and parents (n = 68) were asked to complete a questionnaire using four hypothetical stories to investigate their judgments and reasoning about parent-child situations.
openaire   +3 more sources

Ethno-Religious conflicts and the voices of the past [PDF]

open access: yes, 2012
Rwanda, Kenya, Nigeria. All these African countries are noted for the violence that has become part of their most recent history ( Rwanda’s 1994 conflict and Higazi’s work on the Jos conflict).
Liman, Bala Mohammed
core  

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard   +5 more
wiley   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

open access: yesMolecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed   +10 more
wiley   +1 more source

Mediation in Situations of Conflict and Limited Commitment [PDF]

open access: yes
We study the reasons and conditions under which mediation is beneficial when a principal needs information from an agent to implement an action. Assuming a strong form of limited commitment, the principal may employ a mediator who gathers information and
Kay Mitusch, Roland Strausz
core  

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

ENGLISH-INTERNATIONAL HUMANITARIAN LAW IN A SHARIA DOMNINATED ISLAMIC CONTEXT: ARMED CONFLICT IN PAKISTAN

open access: yesدی اسکالر, 2019
The applicability of International Humanitarian Law (IHL) to the non-international armed conflicts is questioned due to various reasons, mainly the complex nature of such conflicts fulfilling the criteria set under IHL.
Faiz Bakhsh   +2 more
doaj  

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

Conflict-driven reasoning in unions of theories

open access: yes, 2019
Many applications of automated reasoning require decision procedures for the satisfiability of a formula in a theory given by the union of a few theories. Reasoning in a union of theories can be approached in more than one way. The equality-sharing method, also known as Nelson-Oppen scheme, combines decision procedures for the component theories ...
openaire   +1 more source

Home - About - Disclaimer - Privacy