Influenza virus reassortment occurs with high frequency in the absence of segment mismatch. [PDF]
PLoS Pathogens, 2013 Reassortment is fundamental to the evolution of influenza viruses and plays a key role in the generation of epidemiologically significant strains. Previous studies indicate that reassortment is restricted by segment mismatch, arising from functional ...
Nicolle Marshall +4 more
doaj +3 more sources
Using homologous network to identify reassortment risk in H5Nx avian influenza viruses. [PDF]
PLoS Computational BiologyThe resurgence of H5Nx reassortment has caused multiple epidemics resulting in severe disease even death in wild birds and poultry. Assessing H5Nx reassortment risk is crucial for designing targeted interventions and enhancing preparedness efforts to ...
Ruihao Gong, Zijian Feng, Yanyun Zhang
doaj +2 more sources
PLoS Pathogens, 2015 Genetic exchange by a process of genome-segment 'reassortment' represents an important mechanism for evolutionary change in all viruses with segmented genomes, yet in many cases a detailed understanding of its frequency and biological consequences is ...
Kyriaki Nomikou +8 more
doaj +3 more sources
Complex Evolutionary Dynamics of H5N8 Influenza A Viruses Revealed by Comprehensive Reassortment Analysis [PDF]
VirusesInfluenza A viruses (IAVs) circulate among different species and have the potential to cause significant pandemics in humans. This study focuses on reassortment events in the H5N8 subtype of IAV, which poses a serious threat to public health due to its ...
Egor Degtyarev +3 more
doaj +2 more sources
New approaches for unravelling reassortment pathways [PDF]
BMC Evolutionary Biology, 2013 Background Every year the human population encounters epidemic outbreaks of influenza, and history reveals recurring pandemics that have had devastating consequences.
Svinti Victoria +2 more
doaj +2 more sources
Probing orthobunyavirus reassortment using Bunyamwera and Batai viruses as models. [PDF]
PLoS Neglected Tropical DiseasesReassortment is a critical evolutionary mechanism for segmented viruses, enabling the exchange of intact genome segments during co-infection and driving orthobunyavirus evolution; however, the molecular mechanisms underpinning this process remain unclear.
James M Bowen +7 more
doaj +2 more sources
Identification of Reassortment of <i>Orthotospovirus citrullomaculosi</i> in Jiangxi Province, China. [PDF]
VirusesPeng B +5 more
europepmc +3 more sources
Visualizing and deciphering influenza A(H1N1) pdm09 reassortment in the 2019-23 seasons. [PDF]
Virus EvolLi TJ, Chen KF, Pekosz A, Gong YN.
europepmc +3 more sources
A Non-phylogeny-dependent Reassortment Detection Method for Influenza A Viruses
Frontiers in Virology, 2021 Influenza A virus is a segmented RNA virus whose genome consists of 8 single-stranded negative-sense RNA segments. This unique genetic structure allows viruses to exchange their segments through reassortment when they infect the same host cell.
Xingfei Gong +10 more
doaj +1 more source
Reassortment Network of Influenza A Virus
Frontiers in Microbiology, 2021 Influenza A virus (IAV) genomes are composed of eight single-stranded RNA segments. Genetic exchange through reassortment of the segmented genomes often endows IAVs with new genetic characteristics, which may affect transmissibility and pathogenicity of ...
Xingfei Gong +10 more
doaj +1 more source