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Reassortment Network of Influenza A Virus [PDF]
Frontiers in Microbiology, 2021 Influenza A virus (IAV) genomes are composed of eight single-stranded RNA segments. Genetic exchange through reassortment of the segmented genomes often endows IAVs with new genetic characteristics, which may affect transmissibility and pathogenicity of ...
Xingfei Gong +10 more
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Fitness cost of reassortment in human influenza. [PDF]
PLoS Pathogens, 2017 Reassortment, which is the exchange of genome sequence between viruses co-infecting a host cell, plays an important role in the evolution of segmented viruses.
Mara Villa, Michael Lässig
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Influenza A virus reassortment is strain dependent. [PDF]
PLoS Pathogens, 2023 RNA viruses can exchange genetic material during coinfection, an interaction that creates novel strains with implications for viral evolution and public health.
Kishana Y Taylor +10 more
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Using homologous network to identify reassortment risk in H5Nx avian influenza viruses. [PDF]
PLoS Computational BiologyThe resurgence of H5Nx reassortment has caused multiple epidemics resulting in severe disease even death in wild birds and poultry. Assessing H5Nx reassortment risk is crucial for designing targeted interventions and enhancing preparedness efforts to ...
Ruihao Gong, Zijian Feng, Yanyun Zhang
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A Non-phylogeny-dependent Reassortment Detection Method for Influenza A Viruses
Frontiers in Virology, 2021 Influenza A virus is a segmented RNA virus whose genome consists of 8 single-stranded negative-sense RNA segments. This unique genetic structure allows viruses to exchange their segments through reassortment when they infect the same host cell.
Xingfei Gong +10 more
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Influenza virus reassortment occurs with high frequency in the absence of segment mismatch. [PDF]
PLoS Pathogens, 2013 Reassortment is fundamental to the evolution of influenza viruses and plays a key role in the generation of epidemiologically significant strains. Previous studies indicate that reassortment is restricted by segment mismatch, arising from functional ...
Nicolle Marshall +4 more
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Avian Influenza A Viruses Reassort and Diversify Differently in Mallards and Mammals
Viruses, 2021 Reassortment among co-infecting influenza A viruses (IAVs) is an important source of viral diversity and can facilitate expansion into novel host species. Indeed, reassortment played a key role in the evolution of the last three pandemic IAVs.
Ketaki Ganti +7 more
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Frontiers in Microbiology, 2021 Reassortment among avian influenza viruses is the main source of novel avian influenza virus subtypes. Studies have shown that the H9N2 virus often donates internal segments to generate novel reassortant avian influenza viruses, acting as a reassortment ...
Haoyi Yang +10 more
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Genome-Wide Reassortment Analysis of Influenza A H7N9 Viruses Circulating in China during 2013–2019
Viruses, 2022 Reassortment with the H9N2 virus gave rise to the zoonotic H7N9 avian influenza virus (AIV), which caused more than five outbreak waves in humans, with high mortality.
Dongchang He +14 more
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Frontiers in Cellular and Infection Microbiology, 2020 Genomic reassortment of segmented RNA virus strains is an important evolutionary mechanism that can generate novel viruses with profound effects on human and animal health, such as the H1N1 influenza pandemic in 2009 arising from reassortment of two ...
Schuyler W. Liphardt +5 more
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