Results 141 to 150 of about 2,305 (169)

Enhancing Rebaudioside M Synthesis via Introducing Sulfur-Mediated Interactions between Glycosyltransferase UGT76G1 and Rebaudioside D

Journal of Agricultural and Food Chemistry
Rebaudioside M (Reb M), a zero-calorie sweetener with high sweetness, faces production challenges due to its low yield and purity. UGT76G1, a uridine diphosphate glucose (UDPG)-dependent glycosyltransferase, forms a β-1,3-glycosidic bond with rebaudioside D (Reb D) to produce Reb M but with an efficiency lower than that for stevioside (ST).
Fangwei Song, Shengding Wang, Yuanhui Mao, Meiqi Chen, Qingyan Yuan, Suiping Zheng, Shuli Liang, Ying Lin   +7 more
openaire   +2 more sources

Convergent synthesis of steviol glycosides rebaudioside a and M

Carbohydrate Research
Steviol glycosides, a natural health-focused sweetener, is receiving increasing attention. Herein, an efficient and concise approach for the convergent synthesis of Rebaudioside A and M has been devised. This method features a AuCl3-tBuCN cooperative catalysis to achieve highly 1, 2-trans stereoselective glycosidation of a C2-branched trisaccharide ...
Yuanyuan Li, Haoru Zhuang, Xuerui Tao, Yingguo Liu, Tianlu Li, Peng Peng   +5 more
openaire   +2 more sources

A review on rebaudioside M: The next generation steviol glycoside and noncaloric sweetener

Journal of Food Science
Abstract So far, the use of artificial low‐calorie sweeteners, like sucralose, saccharin, and so on, to replace the conventional‐based sugars has not succeeded due to the long‐term adverse health effects, for example, hypertension, and not well‐known safety stand.
Clinton E. Okonkwo, Adeyemi A. Adeyanju, Helen Onyeaka, Charles Obiora Nwonuma, Abiola F. Olaniran, Omokolade Oluwaseyi Alejolowo, Adejumoke A. Inyinbor, Abimbola Peter Oluyori, Cunshan Zhou   +8 more
openaire   +2 more sources

Efficient Conversion of Stevioside to Rebaudioside M in Saccharomyces cerevisiae by a Engineering Hydrolase System and Prolonging the Growth Cycle

Journal of Agricultural and Food Chemistry
Rebaudioside (Reb) M is an important sweetener with high sweetness, but its low content in Stevia rebaudiana and low catalytic capacity of the glycosyltransferases in heterologous microorganisms limit its production. In order to improve the catalytic efficiency of the conversion of stevioside to Reb M by Saccharomyces cerevisiae, several key issues ...
Shan Li, Shuangshuang Luo, Xingying Zhao, Song Gao, Xiaoyu Shan, Jian Lu, Jingwen Zhou   +6 more
openaire   +2 more sources

Fusion glycosyltransferase design for enhanced conversion of rebaudioside A into rebaudioside M in cascade

Molecular Catalysis, 2023
Xiaoqiang Wang, Jiqiang Li, Lina Li, Lipeng Zhu, Fang Huang   +4 more
openaire   +1 more source

Designing an artificially concise biocatalytic cascade for the manufacture of rebaudioside M from a naturally derived steviol glycoside mixture

Green Chemistry
Efficient biosynthesis of Reb M from substrates by designing a concise biosynthetic pathway.
Zhengshan Luo, Xupeng Guo, Zhiwei Deng, Dong Guo, Yan Zhang, Changmei Liu, Zhenbo Yuan, Yijian Rao   +7 more
openaire   +1 more source

Improving the thermostability of glycosyltransferase UGT76G1 by computer-aided target analysis for highly efficient biosynthesis of rebaudioside M

Food Bioscience, 2023
Mengliang Yang, Sai Yang, Zhiwei Deng, Yan Zhang, Zhenbo Yuan, Yijian Rao   +5 more
openaire   +1 more source

Natural and low‐caloric rebaudioside A as a substitute for dietary sugars: A comprehensive review

Comprehensive Reviews in Food Science and Food Safety, 2023
Yang Wang, Clinton Emeka Okonkwo
exaly  

Sweetness profiles of glycosylated rebaudioside A and its binary mixtures with allulose and maltitol

Food Science and Biotechnology, 2021
Jae-Hee Hong
exaly  

Heterologous expression of EUGT11 from Oryza sativa in Pichia pastoris for highly efficient one-pot production of rebaudioside D from rebaudioside A

International Journal of Biological Macromolecules, 2020
Tong Huang, Jia-Lin Meng, Hao Song
exaly