Results 21 to 30 of about 1,681 (87)
Interdisciplinary Medicine, Volume 3, Issue 5, September 2025.Abstract Isothermal amplification (IA) techniques have emerged as promising alternatives to polymerase chain reaction (PCR), enabling rapid and efficient nucleic acid amplification at constant temperatures. Meanwhile, clustered regularly interspaced short palindromic repeat (CRISPR)/Cas‐based technology has revolutionized molecular diagnostics by ...
Miao Liu +7 more
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Microbial Biotechnology, Volume 18, Issue 6, June 2025.Molecular and functional experiments highlight the relevance of species‐specific polymorphisms in a B12 riboswitch of the Mycobacterium genus. This information provided proof‐of‐concept to engineer a whole‐cell biosensor capable of detecting vitamin B12. ABSTRACT Vitamin B12 metabolism differs among members of the Mycobacterium genus.
Elena Campos‐Pardos +6 more
wiley +1 more source
Megalocytivirus: A Review of Epidemiology, Pathogenicity, Immune Evasion, and Prevention Strategies
Reviews in Aquaculture, Volume 17, Issue 3, June 2025.ABSTRACT Megalocytivirus, a large double‐stranded DNA virus belonging to the Iridoviridae family, has infected over 100 species of fish, leading to significant economic losses in the aquaculture, food, and ornamental fish industries. These viruses exhibit icosahedral symmetry and have diameters ranging from 120 to 200 nm.
Changjun Guo +4 more
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Cerebral vascular malformations: pathogenesis and therapy
MedComm, Volume 5, Issue 12, December 2024.CVMs management based on imaging genomics and liquid biopsy. In the future, somatic or de novo germline mutation information could be used to direct neurosurgical and medical management of CVMs. Somatic or germline variants can be acquired from imaging genomics or liquid biopsies preoperatively.
Qiheng He +11 more
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Exploring Advanced CRISPR Delivery Technologies for Therapeutic Genome Editing
Small Science, Volume 4, Issue 10, October 2024.This review examines the potential of clustered regularly interspaced short palindromic repeat (CRISPR) technology in cellular genetics, focusing on challenges like low delivery efficiency and off‐target effects. It discusses innovative carriers—viral, lipid‐based, polymeric particles, and exosomes—that improve stability, reduce side effects, and ...
Neda Rostami +13 more
wiley +1 more source
The Journal of Physiology, Volume 602, Issue 20, Page 5229-5245, 15 October 2024.Abstract figure legend Mavacamten, a myosin‐centred small molecule, directly enhances myosin ATP‐conserving biochemical state in muscle fibres from patients with nemaline myopathy (or mice lacking nebulin). However, in vivo treatment with Mavacamten for 4 weeks (in mice lacking nebulin) does not have significant effects on the muscle fibre energetic ...
Jenni Laitila +12 more
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Molecular Oncology, Volume 19, Issue S1, Page 1-940, June 2025.Abstracts submitted to the ‘EACR 2025 Congress: Innovative Cancer Science’, from 16–19 June 2025 and accepted by the Congress Organising Committee are published in this Supplement of Molecular Oncology, an affiliated journal of the European Association for Cancer Research (EACR).
wiley +1 more source
Minimal mutational requirements for conversion of a telomere resolvase into a Cre-like site-specific recombinase. [PDF]
PLoS OneHuang SH, Kobryn K.
europepmc +1 more source