Results 41 to 50 of about 54,407 (151)

Redox controls RecA protein activity via reversible oxidation of its methionine residues

eLife, 2021
Reactive oxygen species (ROS) cause damage to DNA and proteins. Here, we report that the RecA recombinase is itself oxidized by ROS. Genetic and biochemical analyses revealed that oxidation of RecA altered its DNA repair and DNA recombination activities.
Camille Henry, Laurent Loiseau, Alexandra Vergnes, Didier Vertommen, Angela Mérida-Floriano, Sindhu Chitteni-Pattu, Elizabeth A Wood, Josep Casadesús, Michael M Cox, Frédéric Barras, Benjamin Ezraty   +10 more
doaj   +1 more source

Assessment of Cancer‐Related Cognitive Impairments Across Anti‐Cancer Therapies in a Predominantly Breast Cancer Cohort

International Journal of Cancer, EarlyView.
ABSTRACT Cancer survivors frequently experience cancer‐related cognitive impairment (CRCI), but the contributions of different anti‐cancer therapies remain unclear. Patients with breast or gynaecological cancer were recruited before any anti‐cancer treatment.
Qiqi Lei, Martina E. Schmidt, Philipp Zimmer, Patric Meyer, Andreas Schneeweiss, Karen Steindorf   +5 more
wiley   +1 more source

Transcriptional analysis of the recA gene of Streptococcus thermophilus

Microbial Cell Factories, 2006
Background RecA is a highly conserved prokaryotic protein that not only plays several important roles connected to DNA metabolism but also affects the cell response to various stress conditions.
Cordone Angelina, Baccigalupi Loredana, Giliberti Gabriele, Ricca Ezio, De Felice Maurilio   +4 more
doaj   +1 more source

Differential requirements of two recA mutants for constitutive SOS expression in Escherichia coli K-12. [PDF]

PLoS ONE, 2008
Repairing DNA damage begins with its detection and is often followed by elicitation of a cellular response. In E. coli, RecA polymerizes on ssDNA produced after DNA damage and induces the SOS Response.
Jarukit Edward Long, Nicholas Renzette, Richard C Centore, Steven J Sandler   +3 more
doaj   +1 more source

Movement Disorders in Developmental and Epileptic Encephalopathies

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Monogenic developmental and epileptic encephalopathies (DEE) frequently feature co‐occurring movement disorders. Gene discovery has expanded epilepsy‐dyskinesia syndromes (EDS) from classic associations such as stereotypies in Rett syndrome to PRRT2‐related infantile seizures with paroxysmal dyskinesia and crouched gait in SCN1A ...
Shekeeb Mohammad, Darius Ebrahimi‐Fakhari, Hugo Morales‐Briceno   +2 more
wiley   +1 more source

PcrA Dissociates RecA Filaments and the SsbA and RecO Mediators Counterbalance Such Activity

Frontiers in Molecular Biosciences, 2022
PcrA depletion is lethal in wild-type Bacillus subtilis cells. The PcrA DNA helicase contributes to unwinding RNA from the template strand, backtracking the RNA polymerase, rescuing replication-transcription conflicts, and disassembling RecA from single ...
Begoña Carrasco, María Moreno-del Álamo, Rubén Torres, Juan Carlos Alonso   +3 more
doaj   +1 more source

Sequence alignment of RecA family proteins from ( RadA), (RadA), (Rad51), (Rad51 and Dmc1), (Dmc1 and ScRad51) and (RecA)

, 2011
Copyright information:Taken from "Crystal structure of the left-handed archaeal RadA helical filament: identification of a functional motif for controlling quaternary structures and enzymatic functions of RecA family proteins"Nucleic Acids Research 2007 ...
Yuan-Chih Chang (29676), Ting-Fang Wang (29679), Kuei-An Lin (29677), Chia-Seng Chang (29678), Andrew H.-J. Wang (6728), Tzu-Ping Ko (6724), Li-Tzu Chen (29675)   +6 more
core   +1 more source

Time‐Resolved Effects of Cold Atmospheric Plasma on E. coli GW‐AmxH19 Transcriptome and Proteome in an Emulated Wastewater Environment

PROTEOMICS, EarlyView.
ABSTRACT Cold atmospheric plasma (CAP) is effective against a variety of microorganisms. Here, we described effects on an Escherichia coli strain isolated from hospital wastewater caused by treatment with physical plasma. E. coli GW‐AmxH19 was incubated in artificial wastewater and treated for 15 min with CAP.
Jörg Bernhardt, Dominik Schneider, Julia Rielicke, Susanne Sievers, Veronika Hahn, Mechthild Bömeke, Anja Poehlein, Dirk Albrecht, Juergen F. Kolb, Katharina Riedel, Rolf Daniel, Daniela Zühlke   +11 more
wiley   +1 more source

Biocontrol and plant growth‐promoting potential of Streptomyces strains against fungal pathogens of tomato and wheat for a sustainable agriculture

Pest Management Science, EarlyView.
This study highlights the biocontrol potential of Streptomyces strain Strep_22. In vitro, it inhibits key fungal pathogens by 91.52%. In vivo, it significantly reduces disease incidence in wheat and tomato while enhancing biomass, shoot, and root development, offering a highly promising, sustainable ecological alternative to chemical pesticides ...
Thomas Conte, Maria Grazia Morea, Gaetana Ricciardi, Angelo Pastino, Francesco Lops, Maria Luisa Raimondo, Antonia Carlucci   +6 more
wiley   +1 more source

Structural insights into the inhibition of bacterial RecA by naphthalene polysulfonated compounds

iScience, 2021
Summary: As a promising target for alternative antimicrobials, bacterial recombinase A (RecA) protein has attracted much attention for its roles in antibiotic-driven SOS response and mutagenesis. Naphthalene polysulfonated compounds (NPS) such as suramin
Ziyuan Zhou, Qing Pan, Xinchen Lv, Jing Yuan, Yang Zhang, Ming-Xia Zhang, Ming Ke, Xiao-Mei Mo, Yong-Li Xie, Yingxia Liu, Ting Chen, Mingchan Liang, Feng Yin, Lei Liu, Yiqing Zhou, Kun Qiao, Rui Liu, Zigang Li, Nai-Kei Wong   +18 more
doaj   +1 more source