Results 31 to 40 of about 54,407 (151)
RNA-DNA hybridization promoted by E.coli RecA portein [PDF]
, 1992 RecA protein of E. coli plays a central regulatory role that is induced by damage to DNA and results in the inactivation of LexA repressor. In vitro, RecA protein binds preferentially to single-stranded DNA to form a nucleoprotein filament that can ...
Kirkpatrick, Dwight P. +2 more
core +1 more source
The molecular characterisation of the recA locus in the opportunistic pathogen Bacteroides fragilis [PDF]
, 2012 Bacteroides fragilis is a human gut commensal and an opportunistic pathogen causing anaerobic abscesses and bacteraemias which are treated with the drug, metronidazole, a DNA damaging agent.
Nicholson, Samantha Anne
core +1 more source
Эпидемиология и вакцинопрофилактика, 2015 F. tularensis strain 15/23-1 recA is different from the vaccine strain F. tularensis line 15 NIIEG by lacking one from the two copies of iglC gene and recA gene has reduced its reactogenicity for experimental animals (BALB/c mice and guinea pigs ...
A. N. Mokrievich +11 more
doaj +1 more source
Dynamics and Regulation of RecA Polymerization and De-Polymerization on Double-Stranded DNA. [PDF]
PLoS ONE, 2013 The RecA filament formed on double-stranded (ds) DNA is proposed to be a functional state analogous to that generated during the process of DNA strand exchange.
Hongxia Fu +3 more
doaj +1 more source
Cells, 2021 Mycobacteria exploit at least two independent global systems in response to DNA damage: the LexA/RecA-dependent SOS response and the PafBC-regulated pathway.
Anna Brzostek +8 more
doaj +1 more source
Single Molecule Study of the Polymerization of RecA on dsDNA: The Dynamics of Individual Domains
Frontiers in Molecular Biosciences, 2021 In the Escherichia coli, RecA plays a central role in the recombination and repair of the DNA. For homologous recombination, RecA binds to ssDNA forming a nucleoprotein filament.
Nitzan Maman +6 more
doaj +1 more source
Splitting, joining and cutting : mechanistic studies of enzymes that manipulate DNA [PDF]
, 2010 Electronic version does not contain associated previously published materialDNA is a reactive and dynamic molecule that is continually damaged by both exogenous and endogenous agents.
McRobbie, Anne-Marie M.
core +2 more sources
RecA Regulation by RecU and DprA During Bacillus subtilis Natural Plasmid Transformation
Frontiers in Microbiology, 2018 Natural plasmid transformation plays an important role in the dissemination of antibiotic resistance genes in bacteria. During this process, Bacillus subtilis RecA physically interacts with RecU, RecX, and DprA.
Ester Serrano +4 more
doaj +1 more source
Spatial and temporal organization of RecA in the Escherichia coli DNA-damage response
eLife, 2019 The RecA protein orchestrates the cellular response to DNA damage via its multiple roles in the bacterial SOS response. Lack of tools that provide unambiguous access to the various RecA states within the cell have prevented understanding of the spatial ...
Harshad Ghodke +9 more
doaj +1 more source
Purification and characterization of the RecA protein from Neisseria gonorrhoeae.
PLoS ONE, 2011 The strict human pathogen Neisseria gonorrhoeae is the only causative agent of the sexually transmitted infection gonorrhea. The recA gene from N. gonorrhoeae is essential for DNA repair, natural DNA transformation, and pilin antigenic variation, all ...
Elizabeth A Stohl +3 more
doaj +1 more source