Two Decades of Advances and Limitations in Organ Recellularization [PDF]
Current Issues in Molecular BiologyThe recellularization of tissues after decellularization is a relatively new technology in the field of tissue engineering (TE). Decellularization involves removing cells from a tissue or organ, leaving only the extracellular matrix (ECM).
Alina Stoian +3 more
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Bioengineering of vascularized porcine flaps using perfusion-recellularization [PDF]
Scientific ReportsLarge volume soft tissue defects greatly impact patient quality of life and function while suitable repair options remain a challenge in reconstructive surgery.
Michael S. Xu +6 more
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Functional Recellularization of Acellular Rat Liver Scaffold by Induced Pluripotent Stem Cells: Molecular Evidence for Wnt/B-Catenin Upregulation [PDF]
Cells, 2021 Background. Liver transplantation remains the only viable therapy for liver failure but has a severely restricted utility. Here, we aimed to decellularize rat livers to form acellular 3D bio-scaffolds suitable for seeding with induced pluripotent cells ...
Nesrine Ebrahim +19 more
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Recellularization of decellularized heart valves: Progress toward the tissue-engineered heart valve [PDF]
Journal of Tissue Engineering, 2017 The tissue-engineered heart valve portends a new era in the field of valve replacement. Decellularized heart valves are of great interest as a scaffold for the tissue-engineered heart valve due to their naturally bioactive composition, clinical relevance
Mitchell C VeDepo +3 more
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Enhanced recellularization by using albumin coating with roller bottle cell culture
Regenerative Therapy, 2023 Introduction: The decellularization and recellularization is a promising approach for tissue engineering and regenerative medicine. However, the decellularization process depletes important components like glycosaminoglycans (GAGs), affecting cell ...
Boyun Kim +3 more
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Ex vivo perfusion recellularization of acellular rat hindlimbs for vascular composite allotransplantation [PDF]
Scientific ReportsVascular composite allotransplantation (VCA) is a promising reconstructive surgical option for severe tissue loss. Autologous reconstructive methods are limited by donor tissue availability and donor site morbidity.
Aisha Adil +4 more
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A Review on Bioengineering the Bovine Mammary Gland: The Role of the Extracellular Matrix and Reconstruction Prospects [PDF]
BioengineeringThe mammary gland is a modified sweat gland responsible for milk production. It is affected by diseases that reduce animals’ quality of life, consequently leading to economic losses in livestock.
Fernando Chissico Júnior +6 more
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Decellularization techniques: unveiling the blueprint for tracheal tissue engineering [PDF]
Frontiers in Bioengineering and BiotechnologyCertain congenital or acquired diseases and defects such as tracheo-oesophageal fistula, tracheomalacia, tracheal stenosis, airway ischemia, infections, and tumours can cause damage to the trachea.
Keisha T. Gomes +9 more
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Recellularization of a novel off-the-shelf valve following xenogenic implantation into the right ventricular outflow tract. [PDF]
PLoS ONE, 2017 Current research on valvular heart repair has focused on tissue-engineered heart valves (TEHV) because of its potential to grow similarly to native heart valves.
Ryan S Hennessy +12 more
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A New Method for Preparation of Decellularized Human Scaffolds for Facial Reconstruction [PDF]
Current Issues in Molecular BiologyVascularized composite allotransplantation (VCA) has emerged as a robust alternative for addressing anatomically complex defects but requires a toxic lifelong immunosuppressive regimen. Tissue engineering offers the promise of creating recipient-specific
Elise Lupon +9 more
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