Results 41 to 50 of about 2,128 (154)
A REVIEW OF CELLULARIZATION STRATEGIES FOR TISSUE ENGINEERING OF WHOLE ORGANS
Frontiers in Bioengineering and Biotechnology, 2015 With the advent of whole organ decellularization, extracellular matrix scaffolds suitable for organ engineering were generated from numerous tissues, including the heart, lung, liver, kidney and pancreas, for use as alternatives to traditional organ ...
Michelle E Scarritt +2 more
doaj +1 more source
Easy-to-Assembly System for Decellularization and Recellularization of Liver Grafts in a Bioreactor
Micromachines, 2023 Decellularization of organs creates an acellular scaffold, ideal for being repopulated by cells. In this work, a low-cost perfusion system was created to be used in the process of liver decellularization and as a bioreactor after recellularization.
Maurício Felisberto Borges +2 more
doaj +1 more source
Decellularized Tissue-Engineered Heart Valve Leaflets with Recellularization Potential [PDF]
Tissue Engineering Part A, 2013 Tissue-engineered heart valves (TEHV) have been proposed as a promising solution for the clinical needs of pediatric patients. In vivo studies have shown TEHV leaflet contraction and regurgitation after several months of implantation. This has been attributed to contractile cells utilized to produce the extracellular matrix (ECM) during TEHV culture ...
Zeeshan H, Syedain +4 more
openaire +2 more sources
Applied Sciences, 2020 (1) Background: Decellularized xenogeneic tissues are promising matrices for developing tissue-engineered cardiovascular grafts. In vitro recellularization of these tissues with stromal cells can provide a better in vivo remodelling and a lower ...
Roman Matějka +14 more
doaj +1 more source
Frontiers in Cell and Developmental Biology, 2021 Healing outcomes of meniscal repair are better in younger than in older. However, exact mechanisms underlying superior healing potential in younger remain unclear from a histological perspective.
Wenqiang Yan +38 more
doaj +1 more source
Decellularized scaffold of cryopreserved rat kidney retains its recellularization potential. [PDF]
PLoS ONE, 2017 The multi-cellular nature of renal tissue makes it the most challenging organ for regeneration. Therefore, till date whole organ transplantations remain the definitive treatment for the end stage renal disease (ESRD). The shortage of available organs for
Baldeep Chani +4 more
doaj +1 more source
BMEMat, EarlyView.A novel nanoenzyme based on cerium ions‐tannic acid metal‐polyphenol framework (FCT) has been developed and loaded onto DHVs for targeting M1 macrophages to reduce their ROS level and reprogram macrophage phenotype, thereby eliminating inflammation, promoting endothelialization and adaptive matrix remodeling of scaffolds, offering a promising strategy ...
Peng Song +9 more
wiley +1 more source
PLoS ONE, 2021 Autologous vascular grafts are widely used in revascularization surgeries for small caliber targets. However, the availability of autologous conduits might be limited due to prior surgeries or the quality of vessels.
Shunji Kurokawa +9 more
doaj +1 more source
Optimizing Recellularization of Whole Decellularized Heart Extracellular Matrix
PLoS ONE, 2014 Perfusion decellularization of cadaveric hearts removes cells and generates a cell-free extracellular matrix scaffold containing acellular vascular conduits, which are theoretically sufficient to perfuse and support tissue-engineered heart constructs.
Matthew J Robertson +4 more
openaire +4 more sources
A Two-Step Bioreactor for Lung Recellularization [PDF]
, 2020 AbstractBioreactors for reseeding of decellularized lung scaffolds have evolved with a wide variety of advancements. These include biomimetic mechanical stimulation, constant nutrient flow, multi-output monitoring, and large mammal scaling. Although dynamic bioreactors are not new to the field of bioengineered lungs, ideal conditions during cell ...
Bethany Young +3 more
openaire +1 more source