Results 191 to 200 of about 395,425 (304)

Non‐invasive and efficient diabetic retinal mitochondrial repair nanoplatform based on engineered endothelial mitochondrial‐derived vesicles with dynamic integrated stress response modulation

Interdisciplinary Medicine, EarlyView.
Under hyperglycemic conditions, mitochondrial dysfunction in retinal endothelial cells triggers excessive reactive oxygen species/reactive nitrogen species production, barrier protein degradation, and endothelial barrier breakdown in diabetic retinopathy.
Siyu Gui, Jie Gao, Tianchang Tao, Peng Wang, Zhihao Huang, Yuyang She, Jiajie Li, Jingwan Su, Zhe Lu, Jianchao Qiao, Song Wang, Xiaodong Sun, Mohan Li   +12 more
wiley   +1 more source

Effects of Inhibitors of the Activity of the Circulating Renin-Angiotensin System on the Growth and Proliferation of Endometrial Cancer Cells. [PDF]

Int J Mol Sci
Delforce SJ, Mohammed R, Symington TL, Wang Y, Verrills NM, Lumbers ER, Pringle KG.   +6 more
europepmc   +1 more source

Shear Stress Regulates Angiotensin Type 1 Receptor Expression in Endothelial Cells

Circulation Research, 2009
Bhama Ramkhelawon, J. Vilar, D. Rivas, B. Mees, R. de Crom, A. Tedgui, S. Lehoux   +6 more
semanticscholar   +1 more source

Angiotensin II type 1 receptor (AGTR1; AT1R) [PDF]

Science-Business eXchange, 2009
openaire   +1 more source

Adipose‐derived small extracellular vesicles exacerbate microvascular dysfunction in heart failure with preserved ejection fraction via mmu‐miR‐582‐3p‐mediated Rap1b suppression

Interdisciplinary Medicine, EarlyView.
This study reveals that small extracellular vesicles (sEVs) from visceral fat compromise coronary microcirculation in a mouse model of heart failure with preserved ejection fraction (HFpEF). The SGLT2 inhibitor canagliflozin emerges as a therapeutic strategy, improving cardiac function and endothelial health.
Lu Chen, Qiuhan Wang, Mengjia Shen, Mingjue Li, Yingqi Zhu, Cankun Zheng, Siyuan Ma, Hairuo Lin, Xiaokang Fu, Rui Zhang, Jianping Bin, Yulin Liao, Qiancheng Wang   +12 more
wiley   +1 more source

Modulation of the Renin-Angiotensin System in Critically Ill Patients: Addressing Seven Key Questions for the Intensivist. [PDF]

Anesthesiology
Calabrese A, Bianchi V, Picod A, Bignami EG, Vincent JL, Taccone FS, Annoni F.   +6 more
europepmc   +1 more source

Angiotensin-converting enzyme (ACE); angiotensin II type 1 receptor (AGTR1) [PDF]

Science-Business eXchange, 2009
openaire   +1 more source

Prenatal exposure to antihypertensive medication: A systematic review of neurodevelopmental and educational outcomes

JCPP Advances, EarlyView.
This systematic review investigated the association of prenatal exposure to antihypertensive medication with longer‐term poor neurodevelopmental outcomes by evaluating the findings from existing literature. We undertook a systematic review of previous studies looking specifically at neurodevelopmental outcomes in children.
Shrifah Alkhalaf, Sarjit Singh, Jill P. Pell, Scott M. Nelson, Daniel F. Mackay, Michael Fleming   +5 more
wiley   +1 more source

Role of Angiotensin Receptor Blockers on Cardiovascular Protection in Marfan Syndrome: A Literature Review. [PDF]

Health Sci Rep
Siraj HM, Bidkar SP, Hassan M, Pant N, Ahmad MH, Ali M, Anyagwa OE, Zafar Z, Fayyaz S, Irfan M.   +9 more
europepmc   +1 more source

Differential D1 and D5 Receptor Regulation and Degradation of the Angiotensin Type 1 Receptor

HYPERTENSION, 2008
J. Gildea, Xiaoli Wang, P. Jose, R. Felder   +3 more
semanticscholar   +1 more source