Results 231 to 240 of about 395,425 (304)

The Use of Non‐Selective Beta‐Blockers in Cirrhotic Portal Hypertension

open access: yesPortal Hypertension &Cirrhosis, EarlyView.
Non‐selective beta‐blockers (NSBBs) reduce portal pressure and play a key role in preventing variceal bleeding, managing ascites, and preventing hepatocellular carcinoma (HCC) in cirrhotic patients. Their clinical application requires individualized strategies and further optimization of indications. ABSTRACT Liver cirrhosis is the end stage of various
Tong Bu, Tianyuan Yang, Qi Wang
wiley   +1 more source

Bridging Psychological Stress and Skin Cellular Aging: Flavonoids as a Dual‐Action Therapeutic Strategy

open access: yesPhytotherapy Research, EarlyView.
ABSTRACT Psychological stress (or simply “stress”) is a major contributor to chronic disease worldwide, affecting 35% of the global population, including younger generations. Furthermore, it plays a significant role in human premature aging; hence, its detrimental effects on people's health compel us to comprehend and control the ways in which ...
Marco Duarte   +3 more
wiley   +1 more source

Cardiac disease in systemic sclerosis: Integrating pathobiology with clinical management

open access: yesRheumatology &Autoimmunity, EarlyView.
Abstract Systemic sclerosis (SSc) is a complex autoimmune disorder in which cardiovascular involvement remains a major determinant of morbidity and mortality. Cardiac injury in SSc results from the interplay of microvascular dysfunction, immune‐mediated inflammation, and progressive interstitial and replacement fibrosis, leading to myocardial disease ...
Henry Sutanto, Betty Rachma, Yuliasih
wiley   +1 more source

Autoantibodies directed against the angiotensin II type 1 receptor and the endothelin-1 type A receptor in patients with systemic sclerosis. [PDF]

open access: yesRMD Open
van der Wouden KE   +11 more
europepmc   +1 more source

Recent Advances in Bioconjugation of Aromatic Amino Acid Residues by a Reactivity‐Guided Approach

open access: yesThe Chemical Record, EarlyView.
This review highlights recent advances in the bioconjugation of aromatic amino acids residues, focusing on strategies that leverage their inherent chemical reactivity to enable precise and versatile modifications of biomacromolecules, illustrating relevant applications.
Bruno M. da S. Santos   +3 more
wiley   +1 more source

Attenuation of arsenic trioxide‐induced endothelial injury: unveiling the protective role of ginkgolic acid through inhibition of TRPM4 SUMOylation: Evidence from Raman cellular imaging

open access: yesVIEW, EarlyView.
Inhibiting the SUMOylation modification of TRPM4 can prevent the vascular endothelial damage caused by ATO. Inhibition of TRPM4 SUMOylation, either pharmacologically by GA or genetically by the K618R mutation, protects against ATO‐induced vascular endothelial damage.
Ting‐Ting Tong   +18 more
wiley   +1 more source

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