Results 91 to 100 of about 1,263,611 (221)

Site-specific and time-dependent activation of the endocannabinoid system after transection of long-range projections [PDF]

, 2012
Background: After focal neuronal injury the endocannabinioid system becomes activated and protects or harms neurons depending on cannabinoid derivates and receptor subtypes.
Geisslinger, Gerd, Gerd Geisslinger, Ziebell Simone, Ziebell, Simone, Hobusch, Constance, Koch, Marco, Gerd Geisslinger (109814), Dehghani, Faramarz, Natsuo Ueda, Ueda Natsuo, Dehghani Faramarz, Faramarz Dehghani (109822), Hobusch Constance, Sonja Kallendrusch, Simone Ziebell (109806), Faramarz Dehghani, Koch Marco, Geisslinger Gerd, Ehrlich, Angela, Simone Ziebell, Marco Koch (109817), Angela Ehrlich, Sonja Kallendrusch (109796), Constance Hobusch (109798), Natsuo Ueda (176896), Constance Hobusch, Kallendrusch Sonja, Ehrlich Angela, Kallendrusch, Sonja, Ueda, Natsuo, Marco Koch, Angela Ehrlich (109799)   +31 more
core   +2 more sources

The Neuroprotective Effect of Cannabinoid Receptor Agonist (WIN55,212-2) in Paraoxon Induced Neurotoxicity in PC12 Cells and N-methyl-D-aspartate Receptor Interaction [PDF]

Cell Journal, 2010
Objective: Considering that cannabinoids protect neurons against neurodegeneration, inthis study, the neuroprotective effect of WIN55,212-2 in paraoxon induced neurotoxicity inPC12 cells and the role of the N-methyl-D-aspartate (NMDA) receptor were ...
Hedayat Sahraei, Farideh Bahrami, Soheil Sadri, Leila Golmanesh, Mansoureh Hashemi   +4 more
doaj  

Comparing the Impact of Tetrahydrocannabinol on 30‐Day Readmission Rates and Hospital Length of Stay in Patients With Depression

Brain and Behavior, Volume 16, Issue 9, September 2026.
Among patients hospitalized for major depressive disorder, a positive THC urine drug screen was not independently associated with 30‐day psychiatric readmission or hospital length of stay. These findings suggest that patient factors beyond THC exposure may have a greater influence on hospitalization outcomes.
Mohammed E. Khedr, Yunjin Lee, Muhammed A. Mirza, Humberto Jimenez, Daniel Greer   +4 more
wiley   +1 more source

A lesão dopaminérgica como modelo de estágio pré-motor da doença de Parkinson: efeitos do antagonismo do receptor CB1 [PDF]

, 2012
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas, Programa de Pós-Graduação em Farmacologia, Florianópolis, 2010Além dos sinais motores clássicos, a doença de Parkinson é caracterizada por déficits cognitivos e ...
Tadaiesky, Meigy Tavares
core  

Heterodimerization of apelin receptor and neurotensin receptor 1 induces phosphorylation of ERK1/2and cell proliferationviaGαq-mediated mechanism [PDF]

, 2014
Dimerization of G protein-coupled receptors (GPCRs) is crucial for receptor function including agonist affinity, efficacy, trafficking and specificity of signal transduction, including G protein coupling.
Cai, X, Jiang, Y, Karteris, E, Bai, B, Chen, J, Karteris, Emmanouil, Bai, Bo, Jiang, Yunlu, Cai, Xin, Chen, Jing   +9 more
core   +1 more source

NG2‐Glia in Central Nervous System Following Injury: From Pathological Involvement to Repair Potential

CNS Neuroscience &Therapeutics, Volume 32, Issue 9, September 2026.
Following CNS injury, NG2‐glia display distinct functional phases. In the early stage, NG2‐glia are rapidly activated, proliferate, migrate to the lesion site and secrete CSPGs, which form a chemical and physical barrier that inhibits axonal regeneration.
Yunyun Cai, Xin Shen, Ming Li, Junjie Li, Gang Chen   +4 more
wiley   +1 more source

Efeitos do antagonismo de receptores CB1 sobre a consolidação da memória de medo contextual em diferentes períodos do ritmo circadiano [PDF]

, 2014
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas, Programa de Pós-Graduação em Farmacologia, Florianópolis, 2014.O ritmo circadiano sincroniza as fases inativa e ativa do organismo com a luminosidade do ...
Silva, Rafael Scoz
core  

Differential subcellular recruitment of monoacylglycerol lipase generates spatial specificity of 2-arachidonoyl glycerol signaling during axonal pathfinding [PDF]

, 2010
Peer ...
Klaudia Barabas, Yanagawa, Yuchio, Harkany, Tibor, Giuseppe Tortoriello, Masaaki Torii, Cameron, Gary, Yuchio Yanagawa, Tortoriello, Giuseppe, Gary Cameron, Morozov, Yury M, Watanabe, Masahiko, Masahiko Watanabe, Barabas, Klaudia, Erik Keimpema, Ken Mackie, Keimpema, Erik, Tibor Harkany, Yury M. Morozov, Torii, Masaaki, Mackie, Ken, Watanabe, M, Harkany, T,, Cameron, G, Torii, M, Mackie, K, Tortoriello, G,, Keimpema, E,, Barabas, K, Yanagawa, Y, Morozov, YM   +29 more
core   +1 more source

Untersuchungen zur Rolle des endogenen Cannabinoidsystems bei der Anpassung an aversive Situationen [PDF]

, 2006
Ziel der vorliegenden Arbeit war es zu untersuchen, auf welche Art und Weise das endogene Cannabinoidsystem die Extinktion konditionierter Furcht vermittelt. Dabei gliedert sich diese Arbeit in vier Teile.
Kamprath, Kornelia
core   +1 more source

Cannabinoid‐Inspired Fluorescent Boroisoquinolines for CB1 Receptor Imaging

ChemPhotoChem, Volume 10, Issue 9, September 2026.
A cannabinoid‐inspired fluorescent boroisoquinoline, a low‐micromolar partial agonist of the human CB1 receptor, enabled imaging of CB1 receptors by confocal microscopy in live cells. The intrinsic fluorescence of our probe provides a unique opportunity for CB1 imaging while keeping receptor structure and pharmacology similar to that observed with ...
Dénes Szepesi Kovács, Csilla Nierner, Bettina Szepesi Kovács, Attila Lehotzky, Edina Szűcs, András Dávid Tóth, Dóra Judit Kiss, László Hunyady, György M. Keserű, Péter Ábrányi‐Balogh   +9 more
wiley   +1 more source