Results 91 to 100 of about 22,652 (233)

Circadian disruption elicits sex‐specific gut microbiota, endocannabinoidome, and lipid mediator responses

The FEBS Journal, EarlyView.
Circadian disruption via constant light induces sex‐specific remodeling of the microbiome, lipid mediators, and immune responses. Females exhibit broader gut microbiota alterations, reduced jejunal oxylipins, increased hypothalamic N‐acylethanolamines, and a more inflammatory cytokine profile. Muscle responses are sex‐ and fiber type‐dependent: females
Pejman A. Pashaki, Timothy D. Niepokny, Tina Khalilzadehsabet, Elizabeth Dumais, Nicolas Flamand, Vincenzo Di Marzo, Eric M. Mintz, Cristoforo Silvestri   +7 more
wiley   +1 more source

Motion sickness, stress and the endocannabinoid system [PDF]

, 2010
A substantial number of individuals are at risk for the development of motion sickness induced nausea and vomiting (N&V) during road, air or sea travel.
Kreth Simone, Feuerecker, Matthias, Matthias Feuerecker, Ines Kaufmann, Kaufmann, Ines, Kreth, Simone, Thieme, Detlef, Thieme Detlef, Choukèr Alexander, Schelling Gustav, Feuerecker Matthias, Michael Vogeser, Kaufmann Ines, Vogeser Michael, Manfred Thiel, Schelling, Gustav, Vogeser, Michael, Choukèr, Alexander, Detlef Thieme, Thiel, Manfred, Gustav Schelling, Alexander Choukèr, Daniela Hauer, Thiel Manfred, Hauer, Daniela, Simone Kreth, Hauer Daniela   +26 more
core   +1 more source

CB1 and CB2 Receptor Expression in Type 1 Diabetic Neuropathic Rats Is Enhanced by Photobiomodulation Therapy

Photonics
Background: The interaction between the endocannabinoid system (ECS), specifically the CB1 and CB2 cannabinoid receptors, and neuropathy has aroused great research interest due to the possible implications for treatment.
Danielle Paula Freitas Bataus Silva, Natalia Vendrame, Willians Fernando Vieira, Marucia Chacur   +3 more
doaj   +1 more source

Assessment of Cannabidiol Supplements Use in Small Animals Practice in Portugal

Journal of Animal Physiology and Animal Nutrition, EarlyView.
ABSTRACT This study aimed to assess the current use of cannabidiol supplements (CBDS) by Portuguese small animal veterinary practitioners. An anonymous online survey questioning the frequency of CBDS use, purpose of use and the perceived outcome was developed using Microsoft Forms, and targeted veterinarians currently working in small animal clinics in
Maria Inês Santos, Ana Luísa Lourenço
wiley   +1 more source

Structural insights into cannabinoid receptors CB1 and CB2: determinants of ligand selectivity

Frontiers in Chemical Biology
Cannabinoid receptors 1 (CB1) and 2 (CB2) are key components of the endocannabinoid system and play central roles in regulating diverse physiological processes, including neural signaling, immune modulation, and inflammation. Both receptors belong to the
Ann Varghese, Jie Liu, Wenjing Guo, Tucker A. Patterson, Huixiao Hong   +4 more
doaj   +1 more source

Cannabinoid exposure during pregnancy: Cardiorespiratory effects and offspring outcomes

The Journal of Physiology, EarlyView.
Abstract figure legend Prenatal exposure to cannabinoids has been investigated across human and animal studies to understand its impact on physiological development. Evidence suggests that early‐life cannabinoid exposure influence multiple developmental processes, extending beyond neurodevelopmental outcomes to potentially affect placental function ...
Luis Gustavo A. Patrone, Luciane H. Gargaglioni   +1 more
wiley   +1 more source

Cannabinoids for the control of experimental multiple sclerosis

, 2010
PhDThere have been numerous studies reporting that cannabinoids, both exogenous and endogenous, have a potential beneficial function during incidences of neurological damage.
Pryce, Gareth
core  

O antagonista canabinóide SR141716A facilita a consolidação da memória no labirinto em "T" elevado [PDF]

, 2002
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas. Programa de Pós-Graduação em Farmacologia.Os efeitos do antagonista do receptor canabinóide CB1, SR141716A, nos processos de aprendizado e memória foram ...
Fernandes, Marcelo Soares
core  

Topical and Systemic Cannabidiol Improves Trinitrobenzene Sulfonic Acid Colitis in Mice [PDF]

, 2012
Background/Aims: Compounds of Cannabis sativa are known to exert anti-inflammatory properties, some of them without inducing psychotropic side effects. Cannabidiol (CBD) is such a side effect-free phytocannabinoid that improves chemically induced colitis
Martin Storr, Storr, Martin, Rudolf Schicho, Schicho, Rudolf   +3 more
core   +1 more source

Toxicological properties of Δ9-tetrahydrocannabinol and cannabidiol

Arhiv za Higijenu Rada i Toksikologiju, 2020
Cannabis sativa L. contains more than 100 phytocannabinoids that can interact with cannabinoid receptors CB1 and CB2. None of the cannabinoid receptor ligands is entirely CB1- or CB2-specific. The effects of cannabinoids therefore differ not just because
Černe Katarina
doaj   +1 more source