Results 131 to 140 of about 22,652 (233)

CB1 cannabinoid receptor expressed on astrocytes is required for feeding behaviours and leptin-mediated functions

open access: yes, 2011
While endocannabinoid-mediated regulations of feeding behaviours are generally attributed to neuronal expression of CB1 cannabinoid receptor (CB1), recent data suggested the participation of astrocyte-dependent mechanisms.
Gordon Research Conference on cannabinoid function in the CNS   +1 more
core  

EFFECT OF PALMITOYLATION ON MEMBRANE LOCALISATION AND SIGNALLING OF CB1 CANNABINOID RECEPTOR

open access: yes, 2011
The CB1 cannabinoid receptor is regulated by its association with membrane microdomains like the lipidrafts. The purpose of this study was to investigate the role of CB1 palmitoylation by analyzing the functionalconsequences of site-specific mutation of ...
MACCARRONE, Mauro   +13 more
core  

ROLE OF THE CB1 CANNABINOID RECEPTOR IN BRAFV600E MELANOMA CELLS AND STEM-LIKE CELLS

open access: yes, 2015
Introduction: Human cutaneous melanoma is a skin cancer with high metastatic potential, enhanced heterogeneity, and resistance to chemotherapy. It has been recognized that one of the most important factors responsible for treatment failure is the ...
BRESCHI, MARIA CRISTINA   +6 more
core  

Are endocannabinoid type 1 receptor gene (CNR1) polymorphisms associated with obesity and metabolic syndrome in postmenopausal Polish women?

open access: yes, 2009
Objective: The aim of this study was to determine whether genetic variation at the cannabinoid receptor-1 (CNR1) locus could have an effect on adiposity, fat distribution and obesity-related metabolic disorders in Polish postmenopausal women.Design and ...
Felicja Lwow   +5 more
core  

Receptor-Selective Modulation of Cannabinoid Signaling by Cardamonin: Integrating Molecular Dynamics, Free Energy Calculations, and Behavioral Validation. [PDF]

open access: yesACS Omega
Khalid MH   +7 more
europepmc   +1 more source

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