Results 151 to 160 of about 59,314 (277)
The GPCR Connection: Linking Alzheimer's Disease and Glioblastoma
Journal of Cellular and Molecular Medicine, Volume 30, Issue 7, April 2026.ABSTRACT Alzheimer's disease (AD) and glioblastoma multiforme (GBM) are biologically distinct age‐related brain disorders with opposing clinical phenotypes. AD is characterised by progressive neurodegeneration and cognitive decline, whereas GBM is characterised by aggressive cellular proliferation and a poor prognosis.
Ana B. Caniceiro +4 more
wiley +1 more source
Liver International, Volume 46, Issue 4, April 2026.ABSTRACT Metabolic dysfunction‐associated fatty liver disease (MAFLD), recently redefined from non‐alcoholic fatty liver disease (NAFLD), highlights the central role of metabolic dysfunction in its pathophysiology. The L‐α‐lysophosphatidylinositol/G protein‐coupled receptor 55 (LPI/GPR55) axis, an element of the endocannabinoidome, has emerged as a key
Jerome Lian +3 more
wiley +1 more source
BiologyEndocannabinoids, acting primarily through CB1 receptors, are critical modulators of neuronal activity, influencing cognitive functions and emotional processing.
Giota Tsotsokou +5 more
doaj +1 more source
Cannabidiol is a negative allosteric modulator of the cannabinoid CB1 receptor
British Journal of Pharmacology, 2015 R. Laprairie +3 more
semanticscholar +1 more source
Allosteric Modulation: An Alternate Approach Targeting the Cannabinoid CB1 Receptor
Medicinal research reviews (Print), 2017 Thuy-Ai T Nguyen +5 more
semanticscholar +1 more source
Crystal structures of agonist-bound human cannabinoid receptor CB1
Nature, 2017 T. Hua +18 more
semanticscholar +1 more source
Cannabinoid CB1 receptor; cannabinoid CB2 receptor [PDF]
Science-Business eXchange, 2008 openaire +1 more source