Results 101 to 110 of about 35,026 (238)

The [Tc(N)(PNP)]2+ metal fragment labeled cholecystokinin-8 (CCK8) peptide for CCK-2 receptors imaging: in vitroand in vivo studies [PDF]

, 2007
The radiolabeling of the natural octapeptide CCK8, derivatized with a cysteine residue (Cys-Gly-CCK8), by using the metal fragment [99mTc(N)(PNP3)]2+ (PNP3 = N,N-bis(dimethoxypropylphosphinoethyl)methoxyethylamine) is reported.
Agostini, S, Aloj, L, Arra, C, Aurilio, M, Bolzati, C, CAVAZZA CECCATO, M, Didone, E, Morelli, Giancarlo, Refosco, F, Tesauro, Diego, TORNESELLO A., L   +10 more
core   +1 more source

Cholecystokinin Receptor-Targeted Polyplex Nanoparticle Inhibits Growth and Metastasis of Pancreatic Cancer

Cellular and Molecular Gastroenterology and Hepatology, 2018
Pancreatic ductal adenocarcinoma (PDAC) remains the most aggressive malignancy with the lowest 5-year survival rate of all cancers in part owing to the lack of tumor-specific therapy and the rapid metastatic nature of this cancer.
Julian Burks, Sandeep Nadella, Abdullah Mahmud, Charoen Mankongpaisarnrung, Juan Wang, Jong-In Hahm, Robin D. Tucker, Narayan Shivapurkar, Stephan T. Stern, Jill P. Smith   +9 more
doaj   +1 more source

CRF and urocortin peptides as modulators of energy balance and feeding behavior during stress. [PDF]

, 2014
Early on, corticotropin-releasing factor (CRF), a hallmark brain peptide mediating many components of the stress response, was shown to affect food intake inducing a robust anorexigenic response when injected into the rodent brain.
Stengel, Andreas, Taché, Yvette
core   +3 more sources

Upregulation of CCK3R leading to the suppression of chronic seizures

Translational Psychiatry
Epilepsy is a chronic neurological disorder characterized by recurrent seizures that affect millions globally. Despite the availability of various antiepileptic drugs, 30–40% of patients remain drug-resistant and continue to experience seizures.
Ling He, Liyang Zhang, Yujie Yang, Junming Ren, Zhoujian Xiao, Yihao Li, Yuandi Zhao, Feixu Jiang, Dingxuan Zeng, Xin Yan, Yanyan Sun, Jufang He   +11 more
doaj   +1 more source

Comparative analysis of the hypothalamus transcriptome of laying ducks with different residual feeding intake

Poultry Science
: Feed costs account for approximately 60 to 70% of the cost of poultry farming, and feed utilization is closely related to the profitability of the poultry industry.
Rongbing Guo, Tao Zeng, Dandan Wang, Ayong Zhao, Shiheng Zhou, Zhizhou Huang, Yuguang Chang, Hanxue Sun, Tiantian Gu, Li Chen, Yong Tian, Wenwu Xu, Lizhi Lu   +12 more
doaj   +1 more source

Effect of a Single Nucleotide Polymorphism in the Cholecystokinin Type A Receptor Gene on Growth Traits of the Miyazaki Jitokko Chicken

The Journal of Poultry Science, 2019
The Miyazaki Jitokko chicken, native to the Miyazaki Prefecture in southern Kyushu Island, Japan, is the product of a three-way cross involving the Jitokko, White Plymouth Rock, and Kyushu Rhode breeds. In the present study, associations between a single
Shojiroh Horinouchi, Hiromi Nakayama, Hideaki Takahashi   +2 more
doaj   +1 more source

G-protein-coupled receptors for free fatty acids: nutritional and therapeutic targets [PDF]

, 2014
It is becoming evident that nutrients and metabolic intermediates derived from such nutrients regulate cellular function by activating a number of cell-surface G-protein coupled receptors (GPCRs).
Brian D. Hudson, Graeme Milligan, Hannah Murdoch, Hoveyda, Ma, Saniere, Trond Ulven   +6 more
core   +2 more sources

Cholecystokinin receptor type A are involved in the circadian rhythm of the mouse retina

Heliyon
The retina is the only organ projecting external light to the suprachiasmatic nucleus. Cholecystokinin receptor type A (Cckar/Cckar) is one of the essential factors for light reception in retinal cells. As there was a lack of literature on the matter, we
Yusuke Yamakawa, Yuya Tsurudome, Masaki Tamada, Yuki Tsuchimochi, Yuya Umeda, Yuya Yoshida, Daisuke Kobayashi, Takehiro Kawashiri, Toshio Kubota, Naoya Matsunaga, Takao Shimazoe   +10 more
doaj   +1 more source

Clinical Implications of the 2025–2030 Dietary Guidelines for Americans for Diabetes and Prediabetes Management

Journal of Diabetes, Volume 18, Issue 5, May 2026.
Yoriko Heianza, Frank B. Hu
wiley   +1 more source

Significance of single-nucleotide variants of anorexigenic hormone genes in childhood obesity

Medičnì Perspektivi
Obesity-induced dysregulation of hypothalamic neurons is not completely eliminated by restoring body weight, therefore the most urgent task of modern precision medicine is to predict the trajectory of development of metabolic disorders associated with ...
A.O. Nikulina
doaj   +1 more source