Results 1 to 10 of about 44,776 (142)

Expression of Endothelin-1, Endothelin Receptor-A, and Endothelin Receptor-B in facial melasma compared to adjacent skin

Clinical, Cosmetic and Investigational Dermatology, 2023
Carolina Nunhez da Silva,1 Hélio Amante Miot,1 Tony Fernando Grassi,2 Luciane Alarcão Dias-Melício,2– 4 Leandro Santos,2,3 Ana Cláudia Cavalcante Espósito1 1Department of Dermatology, São Paulo State University (UNESP) - Medical School of Botucatu ...
da Silva CN, Miot HA, Grassi TF, Dias-Melício LA, Santos L, Espósito ACC   +5 more
doaj   +3 more sources

Bosentan, a drug used in the treatment of pulmonary hypertension, can prevent development of osteoporosis [PDF]

Iranian Journal of Basic Medical Sciences, 2021
Objective(s): We examined the antiosteoporotic effect of bosentan (Bose) by radiographic, histopathological, and molecular methods.Materials and Methods: Rats were divided into 4 groups of 8 rats each: one control (Sham), one osteoporosis only (OP), and ...
Duygu Köse, Ahmet Köse, Zekai Halıcı, Elif Çadirci, Taha Tavaci, Muhammed Gürbüz, Adem Maman   +6 more
doaj   +1 more source

Endothelin-1 gene and endothelin receptor A gene polymorphisms in severe pulmonary hypertension associated with rheumatic mitral valve disease

Archives of Medical Science, 2022
Introduction Endothelin-1 (ET-1) gene polymorphisms are implicated in pathogenesis of idiopathic pulmonary arterial hypertension Material and methods We studied ET-1 (Lys198Asn and 3A/4A) and endothelin receptor A (ETA) gene (His323His) polymorphisms in
Pratishtha Mehra, Vimal Mehta, Jamal Yusuf, Rishi Sukhija, Wilbert S. Aronow   +4 more
doaj   +1 more source

Endothelin Receptors and Pain [PDF]

The Journal of Pain, 2009
The endogenous endothelin (ET) peptides participate in a remarkable variety of pain-relatedprocesses. Pain that is elevated by inflammation, by skin incision, by cancer, during a Sickle Cell Disease crisis and by treatments that mimic neuropathic and inflammatory pain and are all reduced by local administration of antagonists of endothelin receptors ...
Khodorova, Alla, Montmayeur, Jean-Pierre, Strichartz, Gary   +2 more
openaire   +4 more sources

Endocan, ET-1, and ETAR Expression Profiles in Unicystic Ameloblastoma, Multicystic Ameloblastoma, and Ameloblastic Carcinoma [PDF]

Middle East Journal of Cancer, 2019
Background: Odontogenic lesions range from simple cysts to benign tumors and carcinomas. Unicystic ameloblastoma is a monocystic lesion and a less aggressive tumor compared to multicystic ameloblastoma.
Soussan Irani, Zhaleh Mohsenifar
doaj   +1 more source

Endothelin‐receptor interactions [PDF]

FEBS Letters, 1993
The mechanism of action of endothelin‐receptor interactions was studied, using radioligand binding assays and SDS‐PAGE, to investigate the possibility of disulfide interchange. Electrophoretic analysis suggested involvement of disulfide bond(s) in the receptor‐ligand complex.
John A. Catena, Michael J. Spinella, Rebecca J. Kottke, Matthew S. Healy, Philip Wilken, Harold I. Magazine, Thomas T. Andersen   +6 more
openaire   +3 more sources

Immunohistochemical Eexpression of Endothelin A Receptor in Dysplastic Oral Mucosa [PDF]

Journal of Kerman University of Medical Sciences, 2020
Background: Recent researches have provided evidences of the importance of endothelin axis in carcinogenesis. According to our knowledge, no data exists about endothelin A receptor (ETA) expression in dysplastic oral mucosa (DOM).
Taymaz Shirali, hamid abbaszadeh, Forough Foroughi, hemmat Gholinia   +3 more
doaj   +1 more source

Genetic interactions between neurofibromin and endothelin receptor B in mice. [PDF]

PLoS ONE, 2013
When mutations in two different genes produce the same mutant phenotype, it suggests that the encoded proteins either interact with each other, or act in parallel to fulfill a similar purpose.
Mugdha Deo, Jenny Li-Ying Huang, Catherine D Van Raamsdonk   +2 more
doaj   +1 more source

Affinity labelling of endothelin receptor and characterization of solubilized endothelin–endothelin‐receptor complex [PDF]

European Journal of Biochemistry, 1990
Chick cardiac membranes were affinity labelled by cross‐linking to membrane‐bound 125I‐endothelin‐1 with disuccinimidyl tartarate. SDS/PAGE and autoradiographic analysis of the 125I‐endothelin‐1‐labelled material in the presence or absence of 2‐mercaptoethanol revealed one major labelled band, corresponding to a molecular mass of 53 kDa, whose ...
Tomoh Masaki, Masami Takahashi, Kazuo Murakami, Yasushi Masuda, Sadao Kimura, Hirotoshi Watanabe, Katsutoshi Goto, Hitoshi Miyazaki, Motohiro Kondoh, Masashi Yanagisawa   +9 more
openaire   +3 more sources

Endothelin B Receptors on Primary Chicken Müller Cells and the Human MIO-M1 Müller Cell Line Activate ERK Signaling via Transactivation of Epidermal Growth Factor Receptors. [PDF]

PLoS ONE, 2016
Injury to the eye or retina triggers Müller cells, the major glia cell of the retina, to dedifferentiate and proliferate. In some species they attain retinal progenitor properties and have the capacity to generate new neurons. The epidermal growth factor
Mohammad Harun-Or-Rashid, Dardan Konjusha, Caridad Galindo-Romero, Finn Hallböök   +3 more
doaj   +1 more source