Abstract figure legend Schematic indicating the design of an acute randomised, counterbalanced, double‐blinded, cross‐over, placebo‐controlled human study in which 20 high‐fit males and 20 low‐fit males consumed either a low‐flavanol (5.6 mg) or a high‐flavanol (695 mg) cocoa drink prior to a 2 h uninterrupted sitting bout.
Alessio Daniele +2 more
wiley +1 more source
Endothelin-2 and Its Association with Uric Acid Levels and Systemic Inflammation: Relevance to Chronic Kidney Disease Progression. [PDF]
Blazhev AB +5 more
europepmc +1 more source
Cardiovascular Dysfunction in Polycystic Ovary Syndrome: Mitochondrial and Inflammatory Mechanisms
Background Polycystic ovary syndrome (PCOS) is a common endocrine disorder that significantly increases cardiovascular disease (CVD) risk in women. While insulin resistance and dyslipidemia are established contributors, growing evidence highlights mitochondrial dysfunction and chronic low‐grade inflammation as central drivers of cardiovascular ...
Olabimpe Caroline Badejogbin +8 more
wiley +1 more source
Protective Effects of Panax ginseng Extract on Endothelin-1- and Isoproterenol-Induced Cardiac Hypertrophy via Maintenance of Mitochondrial Function and Calcium-Reactive Oxygen Species (ROS) Homeostasis. [PDF]
Tagashira H +3 more
europepmc +1 more source
The saphenous vein (SV) remains one of the most widely used grafts in coronary artery bypass grafting (CABG), and the integrity of the endothelium—a complex structure susceptible to deleterious effects from proinflammatory comorbidities—is a critical factor for graft patency. A 75‐year‐old patient with hypertension, dyslipidemia, insulin‐dependent Type
Matheus Duarte Pimentel +3 more
wiley +1 more source
Beyond Viral Assembly: The Emerging Role of HIV-1 p17 in Vascular Inflammation and Endothelial Dysfunction. [PDF]
Pastorello Y +5 more
europepmc +1 more source
The Use of Tranexamic Acid to Treat Melasma: A Systematic Review and Meta‐Analysis
Introduction Tranexamic acid (TXA) is a synthetic derivative of the amino acid lysine that inhibits bleeding due to its effects on plasminogen conversion, approved by the FDA to treat menorrhagia and prevent bleeding in hemophilia patients undergoing dental extraction.
Nabila Scabine Pessotti +7 more
wiley +1 more source
Endothelin antagonists for hypertension: has their time finally arrived? [PDF]
Schiffrin EL.
europepmc +1 more source
Diabetes substantially increases the risk of ischemic stroke through complex metabolic, inflammatory, and vascular mechanisms, yet early identification of high‐risk individuals remains challenging. This narrative review synthesizes emerging circulating and genomic biomarkers that illuminate the pathways linking diabetes and ischemic stroke and ...
Nadia Hussain +4 more
wiley +1 more source
Adipocyte-specific ET<sub>B</sub> receptor overexpression induces obesity, insulin resistance, and dyslipidemia in high-fat diet-fed female mice. [PDF]
Konadu BD +9 more
europepmc +1 more source

