Results 211 to 220 of about 71,317 (233)

Thyroid hormone signaling in ocular development and diseases. [PDF]

Biol Res
Zhang P, Nie Y, Lu NJ, Jiao Q, Wang X, Zhang X, Liu L.   +6 more
europepmc   +1 more source

Loss-of-Function GHSR Variants Are Associated With Short Stature and Low IGF-I.

J Clin Endocrinol Metab
Punt LD, Kooijman S, Mutsters NJM, Yue K, van der Kaay DCM, van Tellingen V, Bakker-van Waarde WM, Boot AM, van den Akker ELT, van Boekholt AA, de Groote K, Kruijsen AR, van Nieuwaal-van Maren NHG, Woltering MC, Heijligers M, van der Heyden JC, Bannink EMN, Rinne T, Hannema SE, de Waal WJ, Delemarre LC, Rensen PCN, de Bruin C, van Duyvenvoorde HA, Visser JA, Delhanty PJD, Losekoot M, Wit JM, Joustra SD.   +28 more
europepmc   +1 more source

Hepatocellular carcinoma: pathogenesis, molecular mechanisms, and treatment advances. [PDF]

Front Oncol
Ding Z, Wang L, Sun J, Zheng L, Tang Y, Tang H.   +5 more
europepmc   +1 more source

Efficacy of cartilage-targeted IGF-1 in a mouse model of growth hormone insensitivity. [PDF]

Front Endocrinol (Lausanne)
Tailor K, van Ree J, Stowe T, Ventura B, Sisk C, Courtis J, Camp A, Elzamzami F, van Deursen J, O'Brien R, Baron J, Lui JC.   +11 more
europepmc   +1 more source

Adrenocortical Carcinoma With 2 Distinct Syndromes From Secretion of Insulin-Like Growth Factor 2 and Steroid Hormones. [PDF]

JCEM Case Rep
Lonergan EM, Tan LYJ, O'Sullivan A, Kanazaki K, Morita M, O'Halloran D.   +5 more
europepmc   +1 more source

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IGF-2 stimulated growth mediated by the somatomedin type 2 receptor

Biochemical and Biophysical Research Communications, 1987
Human Insulinlike Growth Factor 2 (IGF-2) can promote cell proliferation via the type 2 receptor in K562 cells, a human erythroleukemia cell line with IGF-2/type 2 receptors and insulin receptors but lacking IGF-1/type 1 receptors. Cells are grown in semi-solid agar in the absence and presence of increasing amounts of insulin, IGF-1 and IGF-2.
Choh Hao Li, Kerstin Hall, Michael Tally
openaire   +3 more sources

GH regulation of the Type 2 IGF receptor in regenerating skeletal muscle of rats

Journal of Endocrinology, 1996
Abstract GH enhances skeletal muscle growth, and IGF-II peptide is highly expressed during regeneration. We have therefore investigated the effect of GH administration on IGF-II binding and expression in regenerating rat skeletal muscle using the techniques of receptor autoradiography and in situ hybridisation. Notexin, a myotoxin, was injected
J J Bass, P M Dobbie, Jenny M. Oldham, M A Whittle, S P Kirk   +4 more
openaire   +3 more sources

Insulin-like growth factor-II (IGF-II), type 2 IGF receptor, and IGF-binding protein-2 gene expression in rat lung alveolar epithelial cells: relation to proliferation.

Endocrinology, 1994
Pulmonary alveolar type 2 cells act as a reservoir of stem cells which can be induced to proliferate during periods of lung growth and repair after lung injury. Despite the importance of this process, the mechanisms that regulate type 2 cell proliferation have not been well characterized.
K. Chadelat, Annick Clement, Bernard Maitre, Véronique Cazals, Y Le Bouc, Oumel Banine Mouhieddine   +5 more
openaire   +4 more sources

Developmental changes in the expression patterns of IGFs, type 1 IGF receptor and IGF-binding proteins-2 and -4 in perinatal rat lung

Journal of Molecular Endocrinology, 1995
ABSTRACT The insulin-like growth factors (IGF-I and IGF-II), their receptors and binding proteins (IGFBPs) are endogenously expressed in a number of tissues including the lung during fetal and neonatal development. This endogenous autocrine/paracrine IGF 'system', together with endocrine sources, contributes to the regulation of lung cell proliferation.
D. C. Batchelor, M. Klempt, S. J. M. Skinner, A.-M. Hutchins   +3 more
openaire   +3 more sources