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Online-Sourced Retatrutide Complicating Impending Diabetic Ketoacidosis in a Patient With Type 1 Diabetes and Concurrent Shigella Gastroenteritis. [PDF]
Branine N.
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Case report: Tirzepatide-responsive refractory diabetes mellitus in an adult female with prader-willi syndrome. [PDF]
Li S, Yu J, Wei J, Liang M, Liang M.
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[Insulin and insulin receptor disorders].
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Insulin, insulin receptors, and cancer
Journal of Endocrinological Investigation, 2016Insulin is a major regulator of cell metabolism but, in addition, is also a growth factor. Insulin effects in target cells are mediated by the insulin receptor (IR), a transmembrane protein with enzymatic (tyrosine kinase) activity. The insulin receptor, however, is represented by a heterogeneous family of proteins, including two different IR isoforms ...
Vigneri R +2 more
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Ketoacids and the insulin receptor
Diabetes, 1978The binding of insulin to a specific receptor on IM-9-cultured human lymphocytes was studied in vitro under conditions simulating diabetic ketoacidosis. Compared with control incubations at pH 7.4, binding was reduced by 19 per cent at pH 7.1 and by 48 per cent at pH 6.8. Addition of β-hydroxybutyrate, at concentrations similar to those seen clinically,
R I, Misbin +3 more
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