Results 121 to 130 of about 6,476 (207)
In bile duct-ligated (BDL) rats, large cholangiocytes proliferate by activation of cAMP-dependent signaling. Melatonin, which is secreted from pineal gland as well as extrapineal tissues, regulates cell mitosis by interacting with melatonin receptors (MT1 and MT2) modulating cAMP and clock genes.
Anastasia, Renzi +15 more
openaire +3 more sources
GPR50 is the mammalian ortholog of Mel1c: Evidence of rapid evolution in mammals
Background The melatonin receptor subfamily contains three members Mel1a, Mel1b and Mel1c, found in all vertebrates except for Mel1c which is found only in fish, Xenopus species and the chicken.
Malpaux Benoit +6 more
doaj +1 more source
Melatonin MT1 and MT2 receptor expression in Parkinson's disease.
Idiopathic Parkinson disease (PD) is a multi-system disorder with a multifactorial etiology and diverse clinical phenotype. Selective, regional dopaminergic neuronal degeneration in the substantia nigra and other CNS areas including the amygdala are observed in all patients.
Nikhil, Adi +5 more
openaire +1 more source
Research on the effects and related mechanisms of geomagnetic storm on depression
Objective: Depression has become disabling disease in the world. Geomagnetic storm is closely related to depression behavior, and melatonin is an important factor in the pathogenesis of depression. This study observed the effects of different intensities
Hui Wu +8 more
doaj +1 more source
Mammary cancer is a frequent disease in female dogs, where a high proportion of cases correspond to malignant tumors that may exhibit drug resistance. Within the mammary tumor microenvironment, there is a cell subpopulation called cancer stem cells (CSCs)
Dania Cataldo +5 more
doaj +1 more source
Background and purpose: Melatonin is a well-known neuroendocrine reproductive hormone-based hormone that has an important role in the circadian clock system and has potent antioxidant properties.
Mohaddeseh Nemati +5 more
doaj
Light pollution during pregnancy influences the growth of offspring in rats
Objective: To investigate the effects of excessive light exposure during gestation on intrauterine development and early growth of neonates in rats. Methods: Pregnant rats were randomly allocated to three groups: the constant light exposure group, non ...
Baojing Zhao +7 more
doaj +1 more source
The Effect of Melatonin on Behavioral, Molecular, and Histopathological Changes in Cuprizone Model of Demyelination [PDF]
Multiple sclerosis (MS) is an autoimmune, demyelinating disease of the central nervous system. The protective effects of melatonin (MLT) on various neurodegenerative diseases, including MS, have been suggested.
Ghadiri, T. +6 more
core
Environmental Control of Annual Reproductive Cycle and Spawning Rhythmicity of Spinefoots [PDF]
Proceedins of 8th Kuroshio University League Network Formation Toward the Sustainable Society in Kuroshio Region Through Cross-Boader ...
Ayson,Felix +7 more
core
MT1/MT2 melatonin receptors in proinflammatory T helper cell populations
Melatonin, a pineal gland hormone, is an effective regulator of the main T helper Th1 and Th17 populations. Currently, the studies of T helpers are shifting from classical to non-classical variants of these cells, primarily to Th1-polarized Th17 lymphocytes (Th17.1), which are formed in vitro and in vivo by transformation of differentiated Th17 cells ...
Elena M. Kuklina +2 more
openaire +1 more source

