Results 171 to 180 of about 5,798 (220)

Melatonin in Dermatology. [PDF]

open access: yesIndian Dermatol Online J
Relhan V   +4 more
europepmc   +1 more source

Melatonin's oncostatic effects in experimental breast cancer: A systematic review of dose-response and apoptotic mechanisms in animal models. [PDF]

open access: yesClinics (Sao Paulo)
Alves MS   +7 more
europepmc   +1 more source
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Targeting Melatonin MT2 Receptors: A Novel Pharmacological Avenue for Inflammatory and Neuropathic Pain

Current Medicinal Chemistry, 2018
Melatonin (MLT) has been implicated in several pathophysiological states, including pain. MLT mostly activates two G-protein coupled receptors, MT1 and MT2. In this review, we present the analgesic properties of MLT in preclinical and clinical studies, giving particular emphasis to the effects mediated by MT2 receptors and to recent investigations ...
Posa, Luca   +3 more
openaire   +4 more sources

The location, physiology, pathology of hippocampus Melatonin MT2 receptor and MT2-selective modulators

European Journal of Medicinal Chemistry, 2023
Melatonin, a neurohormone secreted by the pineal gland and regulated by the suprachiasmatic nucleus (SCN) of the hypothalamus, is synthesized and directly released into the cerebrospinal fluid (CSF) of the third ventricle (3rdv), where it undergoes rapid absorption by surrounding tissues to exert its physiological function.
Yueqin, Feng   +3 more
openaire   +2 more sources

Tetrahydroisoquinoline derivatives as melatonin MT2 receptor antagonists

Bioorganic & Medicinal Chemistry Letters, 2004
A series of tetrahydroisoquinolines has yielded potent MT(2) receptor antagonists, which are selective versus the MT(1) receptor.
George N, Karageorge   +6 more
openaire   +2 more sources

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