Results 101 to 109 of about 1,546 (109)

Prejunctional muscarine receptors in the rabbit ear artery differ from M1, M2 and M3 muscarine receptors

Naunyn-Schmiedeberg's Archives of Pharmacology, 1992
The ability of several selective muscarine receptor antagonists to inhibit the effect of carbachol on prejunctional muscarine receptors on sympathetic nerve endings in the rabbit isolated ear artery was investigated to characterise the receptor subtype involved.
S A, Darroch, L K, Choo, F, Mitchelson
openaire   +2 more sources

Long-acting muscarinic M3 receptor antagonists.

Expert opinion on therapeutic patents, 2010
A series of 10 closely related patent applications define Theravance's approach to the development of long-acting M(3) selective antagonists for the treatment of chronic obstructive pulmonary disease. The applications illustrate a modular approach to the design of such agents, comprising a muscarinic pharmacophore attached to a second, less ...
openaire   +2 more sources

M1 and M3 muscarinic receptor subtypes in rat forebrain.

Methods and findings in experimental and clinical pharmacology, 1992
At least three pharmacologically different muscarinic receptor subtypes (M1, M2 and M3) have been identified in rat brain. While M1 and M2 subtypes can be directly labelled by selective ligands (3H-pirenzepine and 3H-AF-DX 116, respectively), there are no truly selective ligands for the M3 subtype.
J, Pavia, E, Marquez, S, Laukkonen, F, Martos, A, Gómez, F, Sánchez de la Cuesta   +5 more
openaire   +1 more source

m3-muscarinic receptor specific antisera for use in studies of muscarinic receptor desensitisation

Life Sciences, 1993
A.B. Tobin, S.R. Nahorski
openaire   +1 more source

M3 muscarinic acetylcholine receptor in cardiology and oncology

International Journal of Cardiology, 2014
openaire   +2 more sources

Muscarinic Acetylcholine Receptor M3

2020
openaire   +1 more source

M3 Muscarinic Acetylcholine Receptor

2007
openaire   +1 more source

Ligand-Induced Activation of the M3-Muscarinic Acetylcholine Receptor

This thesis explores the computer-aided drug design of the M3-muscarinic acetylcholine receptor in three chapters. The first chapter focuses on molecular docking to identify novel agonists using the ZINC12 library. A model of the M3 receptor was built based on the M2 receptor.
openaire   +1 more source

Critical Role of M3 Muscarinic Receptor in Insulin Secretion

Journal of Clinical Psychopharmacology, 2006
Ripu D, Jindal, Matcheri S, Keshavan
openaire   +2 more sources