Results 181 to 190 of about 16,615 (204)

[Extracellular Y-box binding protein-1 promotes proliferation and metastasis of HepG2 cells through Notch3 receptor].

Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology, 2017
To clarify whether HepG2 cells actively secrete Y-box binding protein-1 (YB-1) under stress conditions, and to investigate the pathological significance and mechanism of action of extracellular YB-1.HepG2 cells were stimulated and treated by gradient concentrations of lipopolysaccharide (LPS) and adriamycin, the supernatant of the culture solution was ...
J, Shi, P, Li, L, Zou, P, Chen, L P, Zhang   +4 more
openaire   +1 more source

CADASIL associated Notch3 mutations have differential effects both on ligand binding and ligand-induced Notch3 receptor signaling

Aktuelle Neurologie, 2004
A Gschwendtner, N Peters, C Opherk, A Capell, P Gempel, M Dichgans   +5 more
openaire   +1 more source

T-cell specific deregulation of Notch3 receptor induces alterations in the development of myeloid compartment unveiled by the deletion of NF-kappaB/p50 expression

2012
Purpose/Objective: T-cell specific deregulation of Notch3 in transgenicmice (N3-tg), induces the development of a T-cell acute lymphoblastic leukemia (T-ALL), sustained by the constitutive activation of NF-kB canonical pathway. Besides, Notch signalling modulation in bone-marrow stromal cells or in hematopoietic stem cells, has been related to ...
CAMPESE, Antonio Francesco, GRAZIOLI, PAOLA, SCAFETTA, GAIA, NOCE, CLAUDIA, VERKHOVSKAIA, SOFIA, C. Mari, GULINO, Alberto, SCREPANTI, Isabella   +7 more
openaire   +1 more source

Three-tiered EGFr domain risk stratification for individualized NOTCH3-small vessel disease prediction

Brain, 2023
Remco J Hack, Gido Gravesteijn, Minne N Cerfontaine   +2 more
exaly  

Skin biopsy immunostaining with a Notch3 monoclonal antibody for CADASIL diagnosis

Lancet, The, 2001
Anne Joutel, Hugues Chabriat, Anne Ducros   +2 more
exaly  

Strong clustering and stereotyped nature of Notch3 mutations in CADASIL patients

Lancet, The, 1997
Anne Joutel, Christophe Corpechot, Hugues Chabriat   +2 more
exaly  

Protein Kinase Cι Drives a NOTCH3-dependent Stem-like Phenotype in Mutant KRAS Lung Adenocarcinoma

Cancer Cell, 2016
Verline Justilien, Nicole R Murray, Alan P Fields   +2 more
exaly  

954 Rational Effectiveness of Anti-IL-6 Receptor Neutralizing Antibody and NOTCH3 Inhibition in Combination Chemotherapy Targeting Cancer Stem Cell

Gastroenterology, 2012
Ying Jin, Masahiko Tsujii, Jumpei Kondo, Takuya Inoue, Motohiko Kato, Shunsuke Yamamoto, Yoshito Hayashi, Tomofumi Akasaka, Takuya Yamada, Eri Shiraishi, Takahiro Inoue, Akira Mukai, Satoshi Hiyama, Sachiko Nakajima, Shinichiro Shinzaki, Tsutomu Nishida, Kenji Watabe, Hideki Iijima, Tetsuo Takehara   +18 more
openaire   +1 more source

Notch3 mutations in CADASIL, a hereditary adult-onset condition causing stroke and dementia

Nature, 1996
Anne Joutel, Christophe Corpechot, Anne Ducros   +2 more
exaly  

Notch3 in Development, Health and Disease

Biomolecules, 2020
Samira Hosseini Alghaderi, Martin Baron
exaly