Results 311 to 320 of about 148,079 (360)

Influence of Calcium Hydroxide–loaded Microcapsules on Osteoprotegerin and Receptor Activator of Nuclear Factor Kappa B Ligand Activity

Journal of Endodontics, 2014
Calcium hydroxide (Ca[OH]2) microcapsules were synthesized to allow controlled release of Ca(OH)2. The aim of this study was to evaluate the influence of Ca(OH)2 microcapsules on osteoprotegerin (OPG) activity, receptor activator of nuclear factor kappa B ligand (RANKL) activity, and the OPG/RANKL ratio compared with pure Ca(OH)2 powder and Vitapex ...
Bing, Han, Xiaoyan, Wang, Jiguang, Liu, Fuxin, Liang, Xiaozhong, Qu, Zhenzhong, Yang, Xuejun, Gao   +6 more
openaire   +2 more sources

Immunohistochemical study of receptor activator of nuclear factor kappa-B ligand (RANK-L) in human osteolytic bone tumors

Journal of Surgical Oncology, 2002
AbstractBackground and ObjectivesOsteolytic bone tumors produce intercellular signaling proteins that regulate bone remodeling by altering the rates of osteoclast and osteoblast differentiation and activity. This report examines osteolytic bone tumor expression of receptor activator of nuclear factor B‐ligand (RANK‐L), a cytokine that is arguably the ...
Christopher R, Good, Regis J, O'Keefe, J Edward, Puzas, Edward M, Schwarz, Randy N, Rosier   +4 more
openaire   +2 more sources

Receptor activator of nuclear factor kappa B ligand in an experimental intervertebral disc degeneration.

Clinical and experimental rheumatology, 2009
This study was designed to clarify the role of the receptor activator of nuclear factor kappa B ligand (RANKL) in the process of discus degeneration and spondylarthrosis. It was hypothesized that experimental discus lesion would initiate not only local bone remodelling but also increased osteoclast formation on a location remote to the injury site due ...
Z, Mackiewicz, J, Salo, Y T, Konttinen, A, Kaigle Holm, A, Indahl, J, Pajarinen, S, Holm   +6 more
openaire   +1 more source

Receptor Activator of Nuclear Factor Kappa-B-Expressing Mesenchymal Stem Cells-Derived Extracellular Vesicles for Osteoporosis Therapy

ACS Nano
The dynamic balance between bone resorption and formation is critical for maintaining healthy bone homeostasis. However, the receptor activator of the nuclear factor B ligand (RANKL) primarily stimulates mature osteoclasts to resorb bone, and its upregulation leads to osteoporosis in patients.
Wenju Chang, Bo Tian, Qin Qin, Dongxiao Li, Yue Zhang, Chenmeng Zhou, Bingbing Wu, Mingchao Zhang, Huajian Shan, Yichao Ni, Qirong Dong, Chao Wang, Xiao-Zhong Zhou, Jinyu Bai   +13 more
openaire   +2 more sources

High levels of osteoprotegerin and soluble receptor activator of nuclear factor kappa B ligand in serum of rheumatoid arthritis patients and their normalization after anti-tumor necrosis factor alpha treatment.

Arthritis & Rheumatism, 2002
M. Ziółkowska, M. Kurowska, A. Radzikowska, Grazyna Luszczykiewicz, P. Wiland, W. Dziewczopolski, A. Filipowicz-Sosnowska, J. Pazdur, J. Szechiński, J. Kowalczewski, M. Rell-Bakalarska, W. Maslinski   +11 more
semanticscholar   +1 more source

Peptides targeting Receptor activator of nuclear factor-kappa B (RANK) and their applications

2013
The present invention relates to a polypeptide for use as a medicament in the treatment and/or prevention of a disease wherein the RANKL-RANK signaling pathway is involved, in particular a bone resorptive disease.
UNIV NANTES, CHU NANTES
openaire   +1 more source

Receptor activator of nuclear factor kappa B ligand-mediated osteoclastogenesis is elevated in ankylosing spondylitis.

Clinical and experimental rheumatology, 2009
Ankylosing spondylitis (AS) is an inflammatory arthritis involving the axial skeleton. Decreased bone mineral density has also been reported in AS patients. This study sought to determine whether osteoclastogenesis and osteoclast activity are increased in AS.Twenty patients with AS were evaluated using the Bath Ankylosing Spondylitis Disease Activity ...
C H, Im, E H, Kang, J Y, Ki, D W, Shin, H J, Choi, E J, Chang, E Y, Lee, Y J, Lee, E B, Lee, H H, Kim, Y W, Song   +10 more
openaire   +1 more source

Systemic therapy for hormone receptor‐positive/human epidermal growth factor receptor 2‐negative early stage and metastatic breast cancer

Ca-A Cancer Journal for Clinicians, 2023
Laura A Huppert, Hope S Rugo
exaly  

Identification of the osteoprotegerin/receptor activator of nuclear factor-kappa B ligand system in gingival crevicular fluid and tissue of patients with chronic periodontitis.

Journal of Periodontal Research, 2006
Hsein-Kun Lu, Hsein-Kun Lu, Y.-L. Chen, Hong-Chiang Chang, C. Li, M. Kuo   +5 more
semanticscholar   +1 more source

Breast Cancer Statistics, 2022

Ca-A Cancer Journal for Clinicians, 2022
Hyuna Sung, Kimberly D Miller, Rebecca L Siegel   +2 more
exaly