Results 81 to 90 of about 112,514 (282)

Viral modulation of interferon (IFN) responses to african swine fever virus (ASFV) [PDF]

, 2011
Tese de mestrado. Biologia (Biologia Humana e Ambiente). Universidade de Lisboa, Faculdade de Ciências, 2011A imunidade inata constitui a primeira resposta dada por um hospedeiro quando atacado por agentes patogénicos. A resposta imune baseia-se em genes
Costa, Emanuel Nery de Oliveira Quartin, 1986-
core  

Bioactive sphene-based ceramic coatings on cpTi substrates for dental implants: An in vitro study [PDF]

, 2018
Titanium implant surface modifications have been widely investigated to favor the process of osseointegration. The present work aimed to evaluate the effect of sphene (CaTiSiO5) biocoating, on titanium substrates, on the in vitro osteogenic ...
Badocco, Denis, Biasetto, Lisa, Brunello, Giulia, Elsayed, Hamada, Ferroni, Letizia, Gardin, Chiara, Pastore, Paolo, Sivolella, Stefano, Zavan, Barbara   +8 more
core   +2 more sources

Microfluidic Modeling of Macrophage‐Induced Cardiac Inflammation Using NF‐κB Reporter Cardiomyocytes

Advanced Healthcare Materials, EarlyView.
A cardiac inflammation model was developed to enable real‐time analysis of macrophage‐cardiomyocyte interactions using NF‐κB‐reporter cardiomyocytes and a microfluidic co‐culture system. A MATLAB‐based model was implemented to optimize cell density and medium resupply based on TNFα diffusion kinetics. Activation thresholds and stress responses in NF‐κB‐
Chao Liu, Xi Rui Qiang Lu, Seoyoung Jeong, Douglas H. Wu, Rodrigo A. Somoza, Parameswaran Ramakrishnan, Samuel E. Senyo   +6 more
wiley   +1 more source

NEW ASPECTS IN DIAGNOSIS AND TREATMENT OF OSTEOPOROSIS

Zdravniški Vestnik, 2018
Background. Osteoporosis is a disease characterized by low bone mass and microarchitectural deterioration of bone tissue, leading to enhanced bone fragility and a consequent increase in fracture risk.
Damir Franić
doaj   +1 more source

Strontium potently inhibits mineralisation in bone-forming primary rat osteoblast cultures and reduces numbers of osteoclasts in mouse marrow cultures [PDF]

, 2014
The basic mechanisms by which strontium ranelate acts on bone are still unclear. We show that an important action of strontium salts is to block calcification in cultures of osteoblasts, the bone-forming cells.
A Barbara, A Caudrillier, AF Donneau, AS Hurtel-Lemaire, C Roux, D. P. Wornham, E Bonnelye, E Canalis, F Yang, FE McCaslin, G Boivin, GJ Atkins, GM Blake, HB Pan, I Schrooten, I Schrooten, I Schrooten, I. R. Orriss, IR Orriss, IR Orriss, IR Orriss, J Christoffersen, JJ Patel, JY Reginster, JY Reginster, M Grynpas, M Yamaguchi, M. O. Hajjawi, MA Karsdal, MS Rybchyn, N Chattopadhyay, N Takahashi, O Bruyere, O Fromigue, P Ammann, P Zioupos, PC D’Haese, PJ Marie, PJ Marie, PJ Marie, PJ Marie, PJ Meunier, SC Verberckmoes, SC Verberckmoes, T. R. Arnett   +44 more
core   +3 more sources

Simvastatin Restores Uteroplacental Hemodynamics and Trophoblast Function in Obstetric Antiphospholipid Syndrome in a Placenta‐on‐a‐Chip Model

Advanced Healthcare Materials, EarlyView.
Simvastatin mitigates placental hypoperfusion in OAPS by ameliorating abnormal uteromaternal hemodynamics and enhancing trophoblast invasion via optimized endothelial cell interactions under pathological shear stress, as evidenced by results from a placenta‐on‐a‐chip platform.
Hongli Liu, Yuan Wang, Yanjun Cai, Ruixin Guo, Shunhua Liu, Tingting Chen, Tingting Sun, Ruiheng Huo, Tengwei Liu, Qingfeng Lv, Xietong Wang   +10 more
wiley   +1 more source

The Role of Receptor Activator of Nuclear Factor Kappa B (RANK) and Receptor Activator of Nuclear Factor Kappa B Ligand (RANKL) in Osteoporosis Risk: Gene Polymorphism and Soluble RANKL Level in Indonesia Post-Menopausal Women [PDF]

OnLine Journal of Biological Sciences, 2018
Hormonal changes in postmenopausal women may increase osteoclastogenesis that can lead to increased risk of osteoporosis. Receptor Activator of Nuclear factor Kappa B (RANK) and Receptor Activator of Nuclear factor Kappa B Ligand (RANKL) have an important role in osteoclastogenesis that involve in the regulation of bone resorption.
Luluk Yunaini, Dwi Anita Suryandari, Linda Kusdhany, Mala Kurniati, Indhina Reihannisha, Elza Ibrahim Auerkari   +5 more
openaire   +1 more source

The zinc finger protein A20 inhibits TNF-induced NF-kappa B-dependent gene expression by interfering with an RIP- or TRAF2-mediated transactivation signal and directly binds to a novel NF-kappa B-inhibiting protein ABIN. [PDF]

, 1999
A
Ballard, Bandres, Barnes, Bergmann, Beyaert, Boldin, Cao, Carpentier, Chen, Chu, Cooper, Darnay, DeLamarter, De Valck, De Valck, Dignam, Dixit, Eckner, Ferran, Fukushi, Geleziunas, Gerritsen, Harris, Henkel, Heyninck, Hsu, Hsu, Hsu, Hu, Ishida, Ishida, Jäättelä, Kelliher, Krikos, Laherty, Laherty, LeBail, Lee, Malinin, Mercurio, Min, Muzio, Natoli, Naumann, Ng, Niederman, Niwa, Opipari, Perkins, Plaisance, Reinhard, Sarma, Schreck, Semmes, Song, Southern, Uhlik, Van Antwerp, Vandenabeele, Vanden Berghe, W., S. Plaisance, E. Boone, K. De Bosscher, M.L. Schmitz, W. Fiers, and G. Haegeman, Vanhaesebroeck, Van Snick, Vincenz, Yeh, Yin, Yurochko, Zandi, Zhang, Zhong, Zhong   +69 more
core   +2 more sources

Designed Liquid Crystalline Nanoassemblies From Clinically Validated Polyunsaturated Lipids for Combined Antioxidant, Anti‐Apoptotic, and Neurotrophic Treatments

Advanced Healthcare Materials, EarlyView.
Ionizable lipid nanoparticles target multiple pathological pathways in neurodegeneration. The designed self‐assembled materials undergo a pH‐triggered structural transformation from a cubosome/hexosome coexistence to a hexosome phase, enhancing intracellular delivery of a multi‐target phytochemical formulation. The antioxidant‐loaded pH‐responsive LNPs
Thelma Akanchise, Fucen Luo, Borislav Angelov, Yuru Deng, Angelina Angelova   +4 more
wiley   +1 more source

Macrophage Activation: Role of Toll-like Receptors, Nitric Oxide, and Nuclear Factor kappa B

American Journal of Pharmaceutical Education, 2006
Macrophages play an important role in host-defense and inflammation. In response to an immune challenge, macrophages become activated and produce proinflammatory mediators that contribute to nonspecific immunity. The mediators released by activated macrophages include: superoxide anion; reactive nitrogen intermediates, such as nitric oxide and ...
openaire   +3 more sources