Humoral Regulation of Osteoclasts and Their Role in Bone Resorption
Osteoclasts are derived from the macrophage haematopoietic lineage, resemble monocyte-like phagocytic cells, and are involved in bone resorption. The cells of the bone and the immune system communicate by cytokines and growth factors.
Hatice Sebila Dökmetaş
doaj +2 more sources
Background: Orthodontic treatment involves complex bone remodeling, with the Osteoprotegerin (OPG)/Receptor Activator of nuclear factor Kappa-B Ligand (RANKL)/Receptor activator of nuclear factor Kappa-B (RANK) (OPG/RANKL/RANK) signaling pathway ...
Xiaofang Cai +7 more
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In Rats, Whole and Refined Grains Decrease Bone Mineral Density and Content through Modulating Osteoprotegerin and Receptor Activator of Nuclear Factor Kappa B. [PDF]
Sakr H, Khired Z, Moghadas M.
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A review of denosumab for the treatment of osteoporosis
Tsuyoshi Miyazaki,1,2 Fumiaki Tokimura,1 Sakae Tanaka3 1Department of Orthopedic Surgery, 2Department of Geriatric Medicine, Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology, Itabashi-ku, Tokyo, Japan; 3Department of Orthopedic Surgery,
Miyazaki T, Tokimura F, Tanaka S
doaj
Direct and indirect regulation of bone metabolism by lactoferrin
Lactoferrin exerts positive regulation on bone metabolism through both direct and indirect pathways. Directly, it modulates osteoblasts, osteoclasts, and chondrocytes via factors such as insulin-like growth factor (IGF), low-density lipoprotein receptor ...
Yangyang Wu, Cunxin Zhang, Chaoliang Lv
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Lophatherum gracile Bronghiart Suppresses Receptor Activator of Nuclear Factor Kappa-B Ligand-Stimulated Osteoclastogenesis and Prevents Ovariectomy-Induced Osteoporosis. [PDF]
Lee SJ, Jang SA, Kim SC, Ryuk JA, Ha H.
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AIMS/HYPOTHESIS: Our aims were to compare osteoclastic activity between patients with acute Charcot's osteoarthropathy and diabetic and healthy controls, and to determine the effect of the receptor activator of nuclear factor-kappaB ligand (RANKL) and its decoy receptor osteoprotegerin (OPG).
Pandolfi, Franco +4 more
openaire +2 more sources
Expressions of Osteoprotegerin and Receptor Activator of Nuclear Factor Kappa-B Ligand in Alveolar Bone Socket under Low Plasma Estrogen Level Condition [PDF]
Background: Decreasing of estrogen level can lead to alveolar bone loss. This bone loss reflects an imbalance between resorption and apposition. Receptor Activator of Nuclear Factor Kappa-B Ligand (RANKL) is a key mediator in osteoclast activation ...
Agung Krismariono +3 more
doaj
Effects of Lactobacillus reuteri MG5346 on Receptor Activator of Nuclear Factor-Kappa B Ligand (RANKL)-Induced Osteoclastogenesis and Ligature-Induced Experimental Periodontitis Rats. [PDF]
Jeong YJ +4 more
europepmc +1 more source
. » Chronic Charcot arthropathy results from the convergence of genetic predisposition (OPG/RANKL/RANK polymorphisms), metabolic disturbances (AGEs, vitamin D deficiency affecting 84.2% of patients), and inflammatory dysregulation (RANKL/OPG axis, IL-17 ...
Osama Embaby, MSc +3 more
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