Membrane-bound receptor for advanced glycation end products (RAGE) is a stable biomarker of low-quality sperm. [PDF]
Browning J +6 more
europepmc +1 more source
Amelioration of nephritis in receptor for advanced glycation end-products (RAGE)-deficient lupus-prone mice through neutrophil extracellular traps. [PDF]
Watanabe H +15 more
europepmc +1 more source
RAGE Re‐Expressed at Myofibre Level Drives Muscle Wasting in Cancer Conditions
ABSTRACT Background Cancer cachexia (CC) is a highly debilitating syndrome characterized by loss of body and muscle weight affecting most advanced cancer patients. The receptor for advanced glycation end‐products (RAGE) is expressed by several cell types and sustains the inflammatory response in acute and chronic diseases. Total ablation of RAGE (Ager−/
Sara Chiappalupi +10 more
wiley +1 more source
Association between the soluble receptor for advanced glycation end products and diabetes mellitus: systematic review and meta-analysis. [PDF]
Chen Q, Liu L, Ke W, Li X, Xiao H, Li Y.
europepmc +1 more source
Secretome and Pathway Analysis of Stress Induced Disc Degeneration In Vitro
Integrated secretome and phosphoprotein profiling of human nucleus pulposus cells revealed that IL‐1β and TLR2/6 activation induce a shared degenerative program, defined by consistent upregulation of IL‐6, IL‐8, GRO‐α, ICAM‐1, and MMP‐7 and convergence on NF‐κB/AP‐1 signaling.
Exarchos Kanelis +4 more
wiley +1 more source
Role of the receptor for advanced glycation end products in the severity of SARS-CoV-2 infection in diabetic patients. [PDF]
Pedreañez A +2 more
europepmc +1 more source
Exploring and Targeting the Connection of Iron and Copper Homeostasis to Neurodegenerative Diseases
Iron and copper dyshomeostasis, along with their interactions with key intrinsically disordered proteins (e.g., Aβ, tau, α‐synuclein) have a strong implication in the onset and progression of neurodegenerative diseases, including Alzheimer's disease (AD), Parkinson's disease (PD), Prion diseases (PrDs), Huntington's disease (HD), Wilson's disease (WD),
Xin Liu +9 more
wiley +1 more source
Redox Regulation and Oxidative Stress in Health and Disease: Mechanisms and Therapeutic Targeting
Reactive species serve crucial roles which are tightly regulated in both physiological as well as disease states. At physiological levels, these species are integral to redox signaling, while uncontrolled redox promotes disease pathology. This review examines the dysregulation of these processes.
Mohammad Hossein Azadi +2 more
wiley +1 more source
The Receptor for Advanced Glycation End-products in the Mouse Anterior Cingulate Cortex is Involved in Neuron‒Astrocyte Coupling in Chronic Inflammatory Pain and Anxiety Comorbidity. [PDF]
Jiang W +7 more
europepmc +1 more source

