Results 271 to 280 of about 82,871,848 (297)

Cloning and characterization of the canine receptor for advanced glycation end products

Gene, 2006
Metastasis is one of the major problems when dealing with malignant neoplasias. Accordingly, the finding of molecular targets, which can be addressed to reduce tumour metastasising, will have significant impact on the development of new therapeutic approaches.
Hugo, Murua Escobar, Jan T, Soller, Katharina A, Sterenczak, Jan D, Sperveslage, Claudia, Schlueter, Birgit, Burchardt, Nina, Eberle, Melanie, Fork, Rolf, Nimzyk, Susanne, Winkler, Ingo, Nolte, Jörn, Bullerdiek   +11 more
openaire   +2 more sources

Activation of the receptor for advanced glycation end products and consequences on health

Diabetes & Metabolic Syndrome: Clinical Research & Reviews, 2017
Advanced glycation end products (AGE) resulted from a reaction between free amino group of proteins and carbohydrates. This reaction is followed by oxidation and molecular rearrangement. Alternatively AGEs can be produced by glycolysis and oxidation. AGEs bind to a cellular receptor RAGE.
Marie-Paule, Wautier, Pierre-Jean, Guillausseau, Jean-Luc, Wautier   +2 more
openaire   +2 more sources

Advanced Glycation End Product Receptor‐Mediated Cellular Dysfunction

Annals of the New York Academy of Sciences, 2005
Abstract: Advanced glycation end products (AGEs), S100/calgranulins, and HMGB1 proteins supposedly play a pivotal role in diabetes mellitus and other chronic inflammatory diseases by promoting cellular dysfunction via binding to cellular surface receptors.
Angelika, Bierhaus, Per M, Humpert, David M, Stern, Bernd, Arnold, Peter P, Nawroth   +4 more
openaire   +2 more sources

Rage: A Novel Cellular Receptor for Advanced Glycation End Products

Diabetes, 1996
Exposure of proteins to reducing sugars results in nonenzymatic glycation with the ultimate formation of advanced glycation end products (AGEs). One means through which AGEs modulate cellular functions is through binding to specific cell surface acceptor molecules.
A M, Schmidt, O, Hori, R, Cao, S D, Yan, J, Brett, J L, Wautier, S, Ogawa, K, Kuwabara, M, Matsumoto, D, Stern   +9 more
openaire   +2 more sources

Role of receptor for advanced glycation end products in cardiogenic shock*

Critical Care Medicine, 2012
Activation of the receptor for advanced glycation end products by its ligands promotes inflammatory processes and tissue injury. The available evidence suggests that soluble forms of receptor for advanced glycation end products circulating in the plasma may neutralize the ligand-mediated damage by acting as a decoy.
Simina-Ramona, Selejan, Janine, Pöss, Lisa, Hewera, Andrey, Kazakov, Michael, Böhm, Andreas, Link   +5 more
openaire   +2 more sources

Receptor for advanced glycation end-product in ischemia-reperfusion injury

International Immunopharmacology
Ischemia-reperfusion injury (IRI) serves as a pivotal pathological mechanism underlying tissue damage in diverse clinical scenarios, particularly in organ transplantation, and cardiovascular surgery. A key factor in this process is the inflammatory response triggered by the receptor for advanced glycation end-products (RAGE).
Xi, Luo, Qianchao, Hu, Qifa, Ye, Zibiao, Zhong   +3 more
openaire   +2 more sources

Sulforaphane inhibits advanced glycation end product–induced pericyte damage by reducing expression of receptor for advanced glycation end products

Nutrition Research, 2014
Advanced glycation end products (AGEs) not only inhibit DNA synthesis but also play a role in diabetic retinopathy by evoking apoptosis and inflammation in retinal pericytes via interaction with a receptor for AGE (RAGE). Similarly, sulforaphane, which is a naturally occurring isothiocyanate that is found in widely consumed cruciferous vegetables ...
Sayaka, Maeda, Takanori, Matsui, Ayako, Ojima, Masayoshi, Takeuchi, Sho-Ichi, Yamagishi   +4 more
openaire   +2 more sources

Receptor for Advanced Glycation End Products and Soluble Receptor for Advanced Glycation End Products: A Balancing Act in Chronic Obstructive Pulmonary Disease?

American Journal of Respiratory and Critical Care Medicine, 2013
Sukkar, Maria B., Postma, Dirkje S.
openaire   +2 more sources

Advanced glycation end‐products and their receptors: Exercise effects

Obesity Reviews, 2020
Kazuhiko Kotani, Alejandro Gugliucci
openaire   +2 more sources

The Role of Advanced Glycation End Products and Its Soluble Receptor in Kidney Diseases

International Journal of Molecular Sciences, 2022
Marijn Speeckaert, Joris Delanghe, Stephanie Desmedt   +2 more
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