Results 271 to 280 of about 59,203 (302)

Expression of Receptor for Advanced Glycation End Products in Sarcoid Granulomas

American Journal of Respiratory and Critical Care Medicine, 2007
Abstract Rationale The receptor for advanced glycation end products (RAGE) engages a number of ligands implicated in inflammatory processes. The RAGE coding gene maps to the 6p21.32 region, close to the genes DRB1 and BTNL2, which are associated with sarcoidosis.
CAMPO I, MORBINI P, ZORZETTO M, TINELLI C, BRUNETTA E, VILLA C, BOMBIERI C, CUCCIA M, AGOSTINI, CARLO, BOZZI V, FACOETTI A, FERRAROTTI I, MAZZOLA P, SCABINI R, SEMENZATO, GIANPIETRO CARLO, PIGNATTI PF, POZZI E, LUISETTI M.   +17 more
openaire   +4 more sources

Role of receptor for advanced glycation end-products in pathogenesis of psoriasis

Molecular Biology, 2013
This review summarizes the existing knowledge regarding the role of receptor for advanced glycation end products which is a key participant of the inflammatory process, in pathogenesis of psoriasis. By interacting with multiple ligands and activating several signaling mechanisms, receptor for advanced glycation end products regulates gene expression ...
A G, Soboleva, S A, Bruskin, A A, Nikolaev, V V, Sobolev, A V, Mezentsev   +4 more
openaire   +2 more sources

Cellular signalling of the receptor for advanced glycation end products (RAGE)

Cellular Signalling, 2013
The receptor for advanced glycation end-product (RAGE) is the signal transduction receptor which senses a variety of signalling molecules including advanced glycation end products (AGEs), HMGB1, S100/calgranulins, β-amyloid, phosphatidylserine, C3a and advanced oxidation protein products (AOPPs).
Jianling Xie, José D Mendez, Maria Montserrat Aguilar-Hernández   +2 more
exaly   +3 more sources

Receptor for advanced glycation end products (RAGE) in atrial fibrillation

International Journal of Cardiology, 2013
with advanced heart failure. J Am Coll Cardiol 2006;48:2485–9. [9] Okonko DO, Grzeslo A, Witkowski T, et al. Effect of intravenous iron sucrose on exercise tolerance in anemic and nonanemic patients with symptomatic chronic heart failure and iron deficiency: FERRIC-HF: a randomized, controlled, observerblinded trial. JACC 2008;51:103.
Nitin, Mahajan, Veena, Dhawan
openaire   +2 more sources

The receptor for advanced glycation end products: A fuel to pancreatic cancer

Seminars in Cancer Biology, 2018
The receptor for advanced glycation end products (RAGEs) was first illustrated in the year 1992. RAGE is a single-transmembrane and multi-ligand component of the immunoglobulin protein super family. The engagement of RAGE turns out to an establishment of numerous intracellular signalling mechanisms resulting in the progression and perpetuation of many ...
Uzma, Shahab, Mohd Kaleem, Ahmad, Abbas Ali, Mahdi, Mohd, Waseem, Binish, Arif, , Moinuddin, Saheem, Ahmad   +6 more
openaire   +2 more sources

Cloning and characterization of the canine receptor for advanced glycation end products

Gene, 2006
Metastasis is one of the major problems when dealing with malignant neoplasias. Accordingly, the finding of molecular targets, which can be addressed to reduce tumour metastasising, will have significant impact on the development of new therapeutic approaches.
Hugo, Murua Escobar, Jan T, Soller, Katharina A, Sterenczak, Jan D, Sperveslage, Claudia, Schlueter, Birgit, Burchardt, Nina, Eberle, Melanie, Fork, Rolf, Nimzyk, Susanne, Winkler, Ingo, Nolte, Jörn, Bullerdiek   +11 more
openaire   +2 more sources

Activation of the receptor for advanced glycation end products and consequences on health

Diabetes & Metabolic Syndrome: Clinical Research & Reviews, 2017
Advanced glycation end products (AGE) resulted from a reaction between free amino group of proteins and carbohydrates. This reaction is followed by oxidation and molecular rearrangement. Alternatively AGEs can be produced by glycolysis and oxidation. AGEs bind to a cellular receptor RAGE.
Marie-Paule, Wautier, Pierre-Jean, Guillausseau, Jean-Luc, Wautier   +2 more
openaire   +2 more sources

Advanced Glycation End Product Receptor‐Mediated Cellular Dysfunction

Annals of the New York Academy of Sciences, 2005
Abstract: Advanced glycation end products (AGEs), S100/calgranulins, and HMGB1 proteins supposedly play a pivotal role in diabetes mellitus and other chronic inflammatory diseases by promoting cellular dysfunction via binding to cellular surface receptors.
Angelika, Bierhaus, Per M, Humpert, David M, Stern, Bernd, Arnold, Peter P, Nawroth   +4 more
openaire   +2 more sources

Rage: A Novel Cellular Receptor for Advanced Glycation End Products

Diabetes, 1996
Exposure of proteins to reducing sugars results in nonenzymatic glycation with the ultimate formation of advanced glycation end products (AGEs). One means through which AGEs modulate cellular functions is through binding to specific cell surface acceptor molecules.
A M, Schmidt, O, Hori, R, Cao, S D, Yan, J, Brett, J L, Wautier, S, Ogawa, K, Kuwabara, M, Matsumoto, D, Stern   +9 more
openaire   +2 more sources

Role of receptor for advanced glycation end products in cardiogenic shock*

Critical Care Medicine, 2012
Activation of the receptor for advanced glycation end products by its ligands promotes inflammatory processes and tissue injury. The available evidence suggests that soluble forms of receptor for advanced glycation end products circulating in the plasma may neutralize the ligand-mediated damage by acting as a decoy.
Simina-Ramona, Selejan, Janine, Pöss, Lisa, Hewera, Andrey, Kazakov, Michael, Böhm, Andreas, Link   +5 more
openaire   +2 more sources