Results 261 to 270 of about 38,510 (295)

Advanced glycation end products, their receptors and diabetic angiopathy

Journal of the Peripheral Nervous System, 2002
The role of chronic hyperglycemia in the development of diabetic microvascular complications and in neuropathy has been clearly established by intervention studies. However, the biochemical or cellular links between elevated blood glucose levels, and the vascular lesions remain incompletely understood.
J L, Wautier, P J, Guillausseau
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Expression of advanced glycation end‐product receptors in the cochlea

The Laryngoscope, 2010
AbstractObjectives/Hypothesis:Advanced glycation end products (AGE) have recently been implicated in aging changes within different tissues of the body. The role of AGEs and their receptors in the mammalian inner ear is largely unknown. In this study we analyzed for the expression of two AGE receptors, namely RAGE and Ddost (AGE‐R1).Study Design ...
Hanusek, Claudia, Setz, Cristian, Radojevic, Vesna, Brand, Yves, Levano, Soledad, Bodmer, Daniel   +5 more
openaire   +3 more sources

Scavenger Receptors that Recognize Advanced Glycation End Products

Trends in Cardiovascular Medicine, 2002
Scavenger receptors recognize modified low-density lipoproteins (LDLs) such as acetylated LDL and oxidized LDL. Advanced glycation end products (AGE), which are generated through long-term exposure of proteins to glucose, also behave as active ligands for some scavenger receptors, including class A scavenger receptor (SR-A) and class B scavenger ...
Akira, Miyazaki, Hitoshi, Nakayama, Seikoh, Horiuchi   +2 more
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Receptor for Advanced Glycation End Products: Dementia and Cognitive Impairment

Drug Research, 2023
AbstractThe pathophysiological processes of dementia and cognitive impairment are linked to advanced glycation end products (AGEs) and their receptor (RAGE).The neurofibrillary tangles (NFTs) of abnormally hyperphosphorylated tau protein and senile plaques (SPs), which are brought on by ...
Aditya, Singh, Vaseem Ahamad, Ansari, Tarique, Mahmood, Farogh, Ahsan, Rufaida, Wasim, Mohammad, Shariq, Saba, Parveen, Shubhrat, Maheshwari   +7 more
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Receptor for advanced glycation end products in bacterial infection

Current Opinion in Infectious Diseases, 2012
Sepsis is still associated with excess morbidity and mortality worldwide, despite significant advances in critical care medicine. A novel approach is needed in the treatment of sepsis, one that will aim to correct the specific immunologic imbalance that is detrimental to the septic host.As receptor for advanced glycation end products (RAGE) is involved
Christaki, Eirini, Lazaridis, Nikolaos, Opal, Steven M., Christaki, Eirini, Lazaridis, Nikolaos, Opal, Steven M.   +5 more
openaire   +3 more sources

Expression of Receptor for Advanced Glycation End Products in Sarcoid Granulomas

American Journal of Respiratory and Critical Care Medicine, 2007
Abstract Rationale The receptor for advanced glycation end products (RAGE) engages a number of ligands implicated in inflammatory processes. The RAGE coding gene maps to the 6p21.32 region, close to the genes DRB1 and BTNL2, which are associated with sarcoidosis.
CAMPO I, MORBINI P, ZORZETTO M, TINELLI C, BRUNETTA E, VILLA C, BOMBIERI C, CUCCIA M, AGOSTINI, CARLO, BOZZI V, FACOETTI A, FERRAROTTI I, MAZZOLA P, SCABINI R, SEMENZATO, GIANPIETRO CARLO, PIGNATTI PF, POZZI E, LUISETTI M.   +17 more
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Role of receptor for advanced glycation end-products in pathogenesis of psoriasis

Molecular Biology, 2013
This review summarizes the existing knowledge regarding the role of receptor for advanced glycation end products which is a key participant of the inflammatory process, in pathogenesis of psoriasis. By interacting with multiple ligands and activating several signaling mechanisms, receptor for advanced glycation end products regulates gene expression ...
A G, Soboleva, S A, Bruskin, A A, Nikolaev, V V, Sobolev, A V, Mezentsev   +4 more
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Receptor for advanced glycation end products (RAGE) in atrial fibrillation

International Journal of Cardiology, 2013
with advanced heart failure. J Am Coll Cardiol 2006;48:2485–9. [9] Okonko DO, Grzeslo A, Witkowski T, et al. Effect of intravenous iron sucrose on exercise tolerance in anemic and nonanemic patients with symptomatic chronic heart failure and iron deficiency: FERRIC-HF: a randomized, controlled, observerblinded trial. JACC 2008;51:103.
Nitin, Mahajan, Veena, Dhawan
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The receptor for advanced glycation end products: A fuel to pancreatic cancer

Seminars in Cancer Biology, 2018
The receptor for advanced glycation end products (RAGEs) was first illustrated in the year 1992. RAGE is a single-transmembrane and multi-ligand component of the immunoglobulin protein super family. The engagement of RAGE turns out to an establishment of numerous intracellular signalling mechanisms resulting in the progression and perpetuation of many ...
Uzma, Shahab, Mohd Kaleem, Ahmad, Abbas Ali, Mahdi, Mohd, Waseem, Binish, Arif, , Moinuddin, Saheem, Ahmad   +6 more
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Cloning and characterization of the canine receptor for advanced glycation end products

Gene, 2006
Metastasis is one of the major problems when dealing with malignant neoplasias. Accordingly, the finding of molecular targets, which can be addressed to reduce tumour metastasising, will have significant impact on the development of new therapeutic approaches.
Hugo, Murua Escobar, Jan T, Soller, Katharina A, Sterenczak, Jan D, Sperveslage, Claudia, Schlueter, Birgit, Burchardt, Nina, Eberle, Melanie, Fork, Rolf, Nimzyk, Susanne, Winkler, Ingo, Nolte, Jörn, Bullerdiek   +11 more
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