Results 251 to 260 of about 82,871,848 (297)

USP18 Serves as a Key Mediator of cGAS‐STING for Cardiac Aging in Diabetes

Cell Biochemistry and Function, Volume 44, Issue 9, September 2026.
ABSTRACT Diabetes accelerates cardiac aging, but the molecular mechanisms that link metabolic stress to myocardial senescence remain insufficiently defined. This study investigated factors driving diabetes‐associated cardiac aging with a focus on the role of USP18.
Xunxi Deng, Zhiyi Yin, Shi Tai, Hejun Jiang, Yuying Zhou, Yongjun Wang, Liyao Fu   +6 more
wiley   +1 more source

Mechanistic Pathways of Wound Healing: From Hemostasis to Scar‐Free Regeneration

Cell Biochemistry and Function, Volume 44, Issue 9, September 2026.
ABSTRACT Wound healing is the critical process regulated through a harmonious coordination of cellular, molecular, pathological, and systemic communications. Normally, healing occurs in four overlapping phases, which are modified and controlled by various growth factor interactions and signaling pathways.
Devadass Jessy Mercy, Koyeli Girigoswami, Agnishwar Girigoswami   +2 more
wiley   +1 more source

Extracellular high mobility group box 1 as a UV‐induced alarmin driving cutaneous inflammation and photoaging via TLR4 signaling

Journal of Cell Communication and Signaling, Volume 20, Issue 3, September 2026.
UV irradiation triggers the active release of HMGB1 from skin cell nuclei into the extracellular space. Extracellular HMGB1 binds TLR4 receptors on neighboring cells, initiating a signaling cascade that upregulates proinflammatory cytokines (IL‐1β, IL‐6, IL‐8, and TNF‐α). This chronic inflammatory state drives neutrophil infiltration and collagen fiber
Qian Liufu, Zhaoping Qin, Yan Yan, Yiru Xu, Tianyuan He, Yingchun Liu, Yaping Xiang, Chunfang Guo, Taihao Quan   +8 more
wiley   +1 more source

Association of four differently processed diets with plasma and urine advanced glycation end products and serum soluble receptor for advanced glycation end products concentration in healthy dogs. [PDF]

J Anim Physiol Anim Nutr (Berl)
Bridglalsingh S, Archer-Hartmann S, Azadi P, Barbier de La Serre C, Remillard RL, Sunvold GD, Bartges JW.   +6 more
europepmc   +1 more source

Modulation of Soluble Receptor for Advanced Glycation End Products Isoforms and Advanced Glycation End Products in Long-Living Individuals

Biomarkers in Medicine, 2021
Background: Circulating levels of soluble receptor for advanced glycation end products (sRAGE) and advanced glycation end products (AGEs) correlate with aging/cardiovascular risk, which is delayed in long-living individuals (LLIs). AGEs/sRAGE isoforms (cleaved RAGE [cRAGE] and secretory RAGE [esRAGE]) ratio is a valuable marker for disease risk ...
Francesco Scavello, Calogero C Tedesco, Stefania Castiglione, Anna Maciag, Elena Sangalli, Fabrizio Veglia, Gaia Spinetti, Annibale A Puca, Angela Raucci   +8 more
openaire   +3 more sources

Some of the next articles are maybe not open access.

Related searches:

Receptor for advanced glycation end-products in neurodegenerative diseases

Reviews in the Neurosciences, 2015
AbstractThis review, for the first time, aims to summarize the current knowledge in the emerging field of RAGE (receptor for advanced glycation end-products) studies in neurodegeneration and neurodegenerative diseases. RAGE, a member of the multiligand cell surface immunoglobulin family, has been implicated in numerous pathological conditions – from ...
Judyta Juranek, Rashmi Ray, Vivek Rai
exaly   +3 more sources

Advanced glycation end product ligands for the receptor for advanced glycation end products: biochemical characterization and formation kinetics

Analytical Biochemistry, 2004
Advanced glycation end products (AGEs) accumulate with age and at an accelerated rate in diabetes. AGEs bind cell-surface receptors including the receptor for advanced glycation end products (RAGE). The dependence of RAGE binding on specific biochemical characteristics of AGEs is currently unknown.
Valencia, J.V., Weldon, S.C., Quinn, D., Kiers, G.H., Groot, J. de, TeKoppele, J.M., Hughes, T.E.   +6 more
core   +5 more sources

The role of the receptor for advanced glycation end-products in lung fibrosis

American Journal of Physiology - Lung Cellular and Molecular Physiology, 2007
The pathogenesis of pulmonary fibrosis remains unclear. The receptor for advanced glycation end-products (RAGE) is a multi-ligand receptor known to be involved in the process of fibrotic change in several organs, such as peritoneal fibrosis and kidney fibrosis. The aim of this study was to examine the contribution of RAGE during the acute inflammation
Hiroshi Kubo, Yasuhiko Yamamoto, Mutsuo Yamaya   +2 more
exaly   +3 more sources

Understanding RAGE, the receptor for advanced glycation end products

Journal of Molecular Medicine, 2005
Advanced glycation end products (AGEs), S100/calgranulins, HMGB1-proteins, amyloid-beta peptides, and the family of beta-sheet fibrils have been shown to contribute to a number of chronic diseases such as diabetes, amyloidoses, inflammatory conditions, and tumors by promoting cellular dysfunction via binding to cellular surface receptors.
Angelika, Bierhaus, Per M, Humpert, Michael, Morcos, Thoralf, Wendt, Triantafyllos, Chavakis, Bernd, Arnold, David M, Stern, Peter P, Nawroth   +7 more
openaire   +2 more sources

Expression of advanced glycation end‐product receptors in the cochlea

The Laryngoscope, 2010
AbstractObjectives/Hypothesis:Advanced glycation end products (AGE) have recently been implicated in aging changes within different tissues of the body. The role of AGEs and their receptors in the mammalian inner ear is largely unknown. In this study we analyzed for the expression of two AGE receptors, namely RAGE and Ddost (AGE‐R1).Study Design ...
Hanusek, Claudia, Setz, Cristian, Radojevic, Vesna, Brand, Yves, Levano, Soledad, Bodmer, Daniel   +5 more
openaire   +3 more sources