Results 241 to 250 of about 82,871,848 (297)

Electroacupuncture reduces corpus callosum injury in rats with permanent cerebral ischemia by inhibiting the activation of high-mobility group box 1 protein and the receptor for advanced glycation end products. [PDF]

Neuroreport
Li C, Nie Z, Miao H, Wu F, Wang X.
europepmc   +1 more source

Consumer Perceptions of Glycation‐Induced Facial Skin Aging and the Role of Skincare Products

Journal of Cosmetic Dermatology, Volume 25, Issue 10, October 2026.
ABSTRACT Background Glycation is a biological process known to exacerbate undesirable skin aging parameters such as yellowing, dullness, wrinkles and reduced elasticity. This study aimed to better understand consumer perceptions of glycation on facial skin and consumer expectations of anti‐glycation skincare. Methods Focus group discussions (FGDs) with
Sharon Shi, Kelly Chua, Bee Leng Lua
wiley   +1 more source

Hierarchical Collagen Nanofiber Gels Recapitulate a Physiologically Relevant Tumor Stromal Microenvironment

Advanced Healthcare Materials, Volume 15, Issue 34, 11 September 2026.
The collagen nanofiber (CNF) gel supports cancer cell culture, exhibiting cell morphology and cancer‐related protein expression similar to Matrigel. It offers a higher collagen concentration than commercial gels. Additionally, the CNF gel allows replication of the high elasticity of in vivo cancer tissue by controlling collagen fiber sizes, ranging ...
Naoko Sasaki, Tomoyuki Suezawa, Shiro Kitano, Ryohei Katayama, Michiya Matsusaki   +4 more
wiley   +1 more source

Diabetes and the Metabolic Syndrome as Drivers of Neurodegeneration: Convergent Mechanisms Linking Peripheral Neuropathy and Dementia

Annals of Neurology, Volume 100, Issue 3, Page 458-476, September 2026.
The metabolic syndrome, a state of progressive metabolic dysfunction, injures the peripheral and central nervous systems, promoting peripheral neuropathy (PN) and cognitive impairment (CI), respectively. We posit PN and CI are connected in the metabolic syndrome framework, built on the premise that neurons, whether in the peripheral or central nervous ...
Masha G. Savelieff, David L. Bennett, Troels S. Jensen, Eva L. Feldman   +3 more
wiley   +1 more source

Longitudinal importance of the soluble receptor for advanced glycation end-products in nonintubated hospitalized patients with COVID-19 pneumonia.

Am J Physiol Lung Cell Mol Physiol
Wick KD, Siegel L, Oldmixon C, Lundgren JD, Thompson BT, Jones C, Leroux C, Matthay MA, ACTIV-3/TICO Study Group.   +8 more
europepmc   +1 more source

Quantitative EEG‐Based Detection of Poststroke Delirium Endotypes and Their Association With Biomarkers of Inflammation

Brain and Behavior, Volume 16, Issue 9, September 2026.
ABSTRACT Background and Purpose Poststroke delirium (PSD) is common and prognostically relevant, yet under‐detected. Mechanistic and biomarker research is constrained by reliance on an intermittently observed binary phenotype, while delirium reflects one severity level on a continuum of delirium‐related encephalopathy.
Max Blücher, Nursena Armagan, Anna‐Christina Osswald, Annerose Mengel, Antje Vogelgesang, Johanna Ruhnau, Robert Fleischmann   +6 more
wiley   +1 more source

From Traditional Spice to Functional Ingredient: Phenolic Profile and Bioactive Properties of Sicilian Rhus coriaria L. Fruit

Chemistry &Biodiversity, Volume 23, Issue 9, September 2026.
The phenolic composition of Rhus coriaria fruits has been comprehensively characterized and linked to a variety of biological activities, including antioxidant, anti‐glycation, enzyme‐inhibitory, and cytoprotective effects. These findings highlight the functional potential of Sicilian sumac as a valuable source of health‐promoting phytochemicals ...
Katia Arena, Donatella Ambroselli, Roberto Laganà Vinci, Luigi Mondello, Luca Santi, Laura Dugo, Paola Dugo   +6 more
wiley   +1 more source

Antiglycation and Amyloid‐β Inhibitory Activities of Pandanus odorifer Extracts and Isolated Constituents: In Vitro and Molecular Docking Insights

Chemistry &Biodiversity, Volume 23, Issue 9, September 2026.
Pandanus odorifer methanolic extract exhibited strong antiglycation activity, moderate antioxidant capacity, and high flavonoid content. Three isolated compounds reduced Aβ‐associated ThT fluorescence, with blumenol C glucoside showing the greatest effect.
Patricia Marie P. Oliva, Sarleen G. Castro, Joe Anthony H. Manzano, Hayato Ishikawa, Mario A. Tan   +4 more
wiley   +1 more source

Progress in Synthesis and Pharmacology of Telmisartan

Chemistry &Biodiversity, Volume 23, Issue 9, September 2026.
Telmisartan is a benzimidazole derivative and a well‐known drug to treat hypertension. This review provides synthesis and understanding of telmisartan as an antihypertensive drug through two mechanisms of actions: RAAS inhibitor and PPARγ receptor. Effective repurposing of this drug for various diseases like chronic kidney illness, diabetes, fatty ...
Megha, Richa Srivastava, Ram Singh
wiley   +1 more source

Classification, Structure–Activity Relationship, and Anti‐Osteoarthritis Mechanism of Natural Flavonoids

Chemistry &Biodiversity, Volume 23, Issue 9, September 2026.
Natural product flavonoids have a multi‐target therapeutic intervention effect on osteoarthritis. They promote autophagy and cartilage synthesis while alleviating oxidative stress, inhibiting inflammation, and inhibiting matrix degradation. By restoring OPG/RANKL balance and regulating bone metabolism, these compounds synergistically delay the ...
Haibin Wang, Shuqi Zheng, Chunlei Hua, Wanze Feng, Zengxia Liu, Yanhong Sun, Minhui Li   +6 more
wiley   +1 more source