Results 121 to 130 of about 45,545 (290)
Angiotensin-(1-7) Receptor Mas Deficiency Does Not Exacerbate Cardiac Atrophy Following High-Level Spinal Cord Injury in Mice. [PDF]
Front Physiol, 2020 Järve A +5 more
europepmc +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Schema of mechanism of IS-induced Mas receptor downregulation.
, 2014 IS accumulates in HK-2 cells via OAT3. In the cells, IS acts as a ligand of AhR. The IS-AhR complex then interacts with Stat3. In turn, Mas receptor is downregulated by IS-AhR-Stat3 or IS-AhR complex.
Chien-Te Lee (280488) +6 more
core +1 more source
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Interation between the protooncogene mas product and the angiotensin II AT1 receptor
, 2004 1. Em vista de evidencias de que o mas proto-oncogene pode modular as respostas do receptor AT1 a angiotensina II (AngII), o objetivo deste trabalho foi avaliar, por meio de tecnicas de biologia molecular e ensaios farmacologicos, a possivel interacao ...
Santos, Edson Lucas dos [UNIFESP]
core
Envolvimento do receptor FPR2/ALX nas alterações vasculares induzidas por LPS e SEPSE [PDF]
, 2015 Tese (doutorado) - Universidade Federal de Santa catarina, Centro de Ciências Biológicas, Programa de Pós-Graduação em Biotecnologia e Biociências, Florianópolis, 2015.O FPR2/ALX é um receptor acoplado à proteína G pertencente à família dos receptores de
Horewicz, Verônica Vargas
core
Alterations in gene expression in the testis of angiotensin-(1�7)-receptor Mas-deficient mice
, 2007 The Mas protooncogene encodes a G-protein coupled receptor with seven trans-membrane domains and was recently described as a receptor for angiotensin-(1 7).
Xu, P. +3 more
core +1 more source
FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source