Angiotensin-(1-7) improves skeletal muscle regeneration [PDF]
European Journal of Translational Myology, 2023 Skeletal muscle possesses regenerative potential via satellite cells, compromised in muscular dystrophies leading to fibrosis and fat infiltration. Angiotensin II (Ang-II) is commonly associated with pathological states.
Mayalen Valero-Breton +5 more
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Central angiotensin 1–7 triggers brown fat thermogenesis [PDF]
Physiological Reports, 2023 We tested the hypothesis that third ventricular (3V) injections of angiotensin 1–7 (Ang 1–7) increases thermogenesis in brown adipose tissue (BAT), and whether the Mas receptor mediates this response.
F. S. Evangelista, T. J. Bartness
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Angiotensin 1–7 in an experimental septic shock model [PDF]
Critical Care, 2023 Background Alterations in the renin–angiotensin system have been implicated in the pathophysiology of septic shock. In particular, angiotensin 1–7 (Ang-(1–7)), an anti-inflammatory heptapeptide, has been hypothesized to have beneficial effects.
Bruno Garcia +12 more
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Pharmacological Effects of Angiotensin 1–7 on Venous Vascular Tone [PDF]
BiomedicinesBackground/Objectives: The ACE2/Ang-(1–7)/Mas receptor axis is a protective, counter-regulatory component of the RAAS that opposes Ang II/AT1R-mediated vasoconstriction.
Armond Daci +5 more
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Maternal plasma angiotensin 1-7 concentration is related to twin pregnancy chorionicity in the third trimester of pregnancy [PDF]
Frontiers in Endocrinology, 2023 IntroductionTwin gestation is related to a higher risk of hypertensive disorders in pregnancy with possible risk stratification depending on chorionicity.
Paweł Pietruski +6 more
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Upregulation of angiotensin-(1-7) formation in human podocytes - enzyme activity assay upon fluid flow shear stress. [PDF]
PLoS ONEThe renin-angiotensin system is known for its role in renal physiology by regulating renal hemodynamics and natriuresis. Overactivation of this system exerts pathological effects in the kidney, primarily mediated by its main effector peptide angiotensin ...
Debora Kaiser-Graf +4 more
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Angiotensin-(1–7) suppresses pyroptosis in cerebral endothelium to decrease blood–brain barrier permeability and cognitive impairments in sepsis [PDF]
Journal of International Medical ResearchObjective This study aimed to explore the influence of the angiotensin-(1–7)/Mas receptor and angiotensin II/angiotensin II type 1 receptor pathways on pyroptosis during sepsis and their subsequent effects on cognitive function.
Yongli Han +7 more
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Angiotensin 1-7 and losartan worsen the cisplatin induced nephrotoxicity in female rats [PDF]
Journal of Nephropharmacology, 2022 Introduction: Cisplatin (CP) is an anti-cancer drug with the most common side effects of nephrotoxicity. Losartan, an angiotensin II type 1 receptor (AT1R) antagonist and angiotensin 1-7 (Ang1-7) protects the kidney against CP administration in males ...
Sayyedehnikta Kasaei +6 more
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Pharmaceutics, 2022 The COVID-19 pandemic has put a tremendous stress on the medical community over the last two years. Managing the infection proved a lot more difficult after several research communities started to recognize the long-term effects of this disease.
Minela Aida Maranduca +7 more
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Physiological Reports, 2021 Cardiovascular diseases are the principal cause of death worldwide, with hypertension being the most common cardiovascular disease risk factor. High blood pressure (BP) is also associated with an increased risk of poor cognitive performance and dementia ...
Filipe F. Stoyell‐Conti +4 more
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