Results 11 to 20 of about 311,335 (299)
Antihypertensive effects of angiotensin-(1-7) [PDF]
Brazilian Journal of Medical and Biological Research, 1998 Accumulating evidence suggests that angiotensin-(1-7) (Ang-(1-7)) is an important component of the renin-angiotensin system and that the actions of the peptide may either contribute to or oppose those of Ang II.
M.C. Chappell +3 more
doaj +6 more sources
Cardiovascular actions of angiotensin-(1-7) [PDF]
Brazilian Journal of Medical and Biological Research, 2005 Angiotensin-(1-7) (Ang-(1-7)) is now considered to be a biologically active member of the renin-angiotensin system. The functions of Ang-(1-7) are often opposite to those attributed to the main effector component of the renin-angiotensin system, Ang II ...
Ferreira A.J., Santos R.A.S.
doaj +6 more sources
Angiotensin-(1-7) is a modulator of the human renin-angiotensin system [PDF]
Hypertension, 1999 The renin-angiotensin system is important for cardiovascular homeostasis. Currently, therapies for different cardiovascular diseases are based on inhibition of angiotensin-converting enzyme (ACE) or angiotensin II receptor blockade.
van Gilst, WH +6 more
core +5 more sources
Renal actions of angiotensin-(1-7) [PDF]
Brazilian Journal of Medical and Biological Research, 1997 The heptapeptide angiotensin-(1-7) is considered to be a biologically active endproduct of the renin-angiotensin system. This angiotensin, which is devoid of the most known actions of angiotensin II such as induction of drinking behavior and ...
A.C. Simões-e-Silva +3 more
doaj +3 more sources
The ACE2/angiotensin-(1-7)/MAS axis of the renin-angiotensin system: focus on angiotensin-(1-7) [PDF]
Physiological Reviews, 2018 The renin-angiotensin system (RAS) is a key player in the control of the cardiovascular system and hydroelectrolyte balance, with an influence on organs and functions throughout the body.
Alenina, N. +20 more
core +3 more sources
The Journal of Pharmacology and Experimental Therapeutics, 2009 The in vivo efficacy of many therapeutic peptides is hampered by their rapid proteolytic degradation. Cyclization of these therapeutic peptides is an excellent way to render them more resistant against breakdown.
Walther, Thomas +9 more
core +3 more sources
Therapeutic uses for Angiotensin-(1-7)
Expert Opinion on Therapeutic Patents, 2016 Angiotensin-(1-7) is a key component of the Renin-Angiotensin System, which can counter-regulate several deleterious effects caused by angiotensin II. Due to the potential for therapeutic use, several of its actions are specifically described in patents.
Sinisterra, Rubén Dario +3 more
core +3 more sources
Physiological and pathological roles of Ang II and Ang- (1-7) in the female reproductive system
Frontiers in Endocrinology, 2022 The local Renin-Angiotensin System (RAS) has been demonstrated to exist in a wide range of tissues and organs, In the female reproductive system, it is mainly found in the ovary, uterus and placenta.
Yuanyuan Liu +8 more
doaj +1 more source
Journal of Veterinary Internal Medicine, 2021 Background Little is known about the effect of renin angiotensin aldosterone system‐inhibiting (RAASi) drugs on alternative angiotensin peptides (APs) such as angiotensin 1‐7 (Ang1‐7), which are mediated by angiotensin‐converting enzyme 2 (ACE2 ...
Terry Huh +3 more
doaj +1 more source
Pharmaceuticals, 2022 Rheumatoid arthritis (RA) is a chronic inflammatory condition of synovial joints that causes disability and systemic complications. Ang-(1-7), one of the main peptides in the renin-angiotensin (Ang) system (RAS), imposes its protective effects through ...
Sana Khajeh pour +3 more
doaj +1 more source