Results 21 to 30 of about 34,610,957 (287)
Pharmaceuticals, 2022 Rheumatoid arthritis (RA) is a chronic inflammatory condition of synovial joints that causes disability and systemic complications. Ang-(1-7), one of the main peptides in the renin-angiotensin (Ang) system (RAS), imposes its protective effects through ...
Sana Khajeh pour +3 more
doaj +1 more source
The angiotensin-converting enzyme (ACE) gene family of Anopheles gambiae. [PDF]
, 2005 Background Members of the M2 family of peptidases, related to mammalian angiotensin converting enzyme (ACE), play important roles in regulating a number of physiological processes.
Isaac, R. Elwyn +4 more
core +6 more sources
Angiotensin 1‐7 protects against ventilator‐induced diaphragm dysfunction
Clinical and Translational Science, 2021 Mechanical ventilation (MV) is a life‐saving instrument used to provide ventilatory support for critically ill patients and patients undergoing surgery.
Toshinori Yoshihara +5 more
doaj +1 more source
The vascular renin-angiotensin-aldosterone system [PDF]
, 2001 PhDThe renin-angiotensin-aldosterone system (RAAS) is one of the major regulators of blood pressure. The actions and generation of RAAS components at the tissue level are less well appreciated.
Xiao, Fang
core +4 more sources
Metabolism of Angiotensin-(1–7) by Angiotensin-Converting Enzyme [PDF]
Hypertension, 1998 Angiotensin converting enzyme (ACE) inhibitors augment circulating levels of the vasodilator peptide angiotensin-(1–7) [Ang-(1–7)] in man and animals. Increased concentrations of the peptide may contribute to the antihypertensive effects associated with ACE inhibitors.
M C, Chappell +3 more
openaire +2 more sources
Adenoviral delivery of angiotensin-(1-7) or angiotensin-(1-9) inhibits cardiomyocyte hypertrophy via the mas or angiotensin Type 2 receptor [PDF]
, 2012 The counter-regulatory axis of the renin angiotensin system peptide angiotensin-(1-7) [Ang-(1-7)] has been identified as a potential therapeutic target in cardiac remodelling, acting via the mas receptor.
Nicklin Stuart A. +11 more
core +2 more sources
Hypertension, 2014 In the last decade, a substantial change in our understanding of the renin–angiotensin system (RAS) occurred.1,2 It is now clear that the circulating and tissue RAS are far more complex than previously anticipated. The modern concept of the RAS includes, in addition to the classical components (renin, angiotensin [Ang]-converting enzyme [ACE], Ang II ...
openaire +2 more sources
Astroglia are a possible cellular substrate of angiotensin(1-7) effects in the rostral ventrolateral medulla [PDF]
, 2010 AIMS: Angiotensin(1-7) (Ang1-7) acting at the level of the rostral ventrolateral medulla (RVLM) affects arterial pressure. The cellular substrate of Ang1-7 remains unknown.
Tang, F +15 more
core +1 more source
Electronic sculpting of ligand-GPCR subtype selectivity:the case of angiotensin II [PDF]
, 2014 GPCR subtypes possess distinct functional and pharmacological profiles, and thus development of subtype-selective ligands has immense therapeutic potential.
Pappas, Charalampos G. +41 more
core +1 more source
Journal of Veterinary Internal Medicine, 2021 Background The pathophysiology of heart failure involves maladaptive angiotensin peptides (APs) and enzymes, including angiotensin 2 (AT2) and angiotensin converting enzyme (ACE), as well as recently described alternative components, such as angiotensin ...
Éva Larouche‐Lebel +3 more
doaj +1 more source