Results 191 to 200 of about 396,884 (345)

Staphylococcal enterotoxins modulate interleukin 2 receptor expression and ligand-induced tyrosine phosphorylation of the Janus protein-tyrosine kinase 3 (Jak3) and signal transducers and activators of transcription (Stat proteins).

, 1995
Michael Engelbrecht Nielsen, Arne Svejgaard, C. Röpke, Mette Nordahl, N Odum   +4 more
openalex   +1 more source

Substrates of semicarbazide-sensitive amine oxidase co-operate with vanadate to stimulate tyrosine phosphorylation of insulin-receptor-substrate proteins, phosphoinositide 3-kinase activity and GLUT4 translocation in adipose cells [PDF]

, 2000
Gemma Enrique-Tarancón, Isabelle Castan‐Laurell, Nathalie Morin, Luc Marti, Anna Abella, Marta Camps, Roser Casamitjana, Manuel Palacı́n, Xavier Testar, Eva Degerman, Christian Carpéné, António Zorzano   +11 more
openalex   +1 more source

Tracing and Capturing the Epiblast Pluripotency of Sheep Preimplantation Embryos

Advanced Science, EarlyView.
This study performs a comprehensive single‐cell transcriptome analysis of sheep embryos from embryonic (E) day 1 to E14 to elucidate the mechanism of early lineage specification and the pluripotency changes (naïve, formative, and primed) of epiblast.
Jinying Zhang, Runbo Li, Ruijie Luo, Qiang Zhang, Zimo Zhao, Haishen Xu, Minglei Zhi, Wenjie Jiang, Meng Wang, Xinze Chen, Zhiqiang Feng, Yingjie Wang, Yuhan Yang, Pengcheng He, Hanyue Su, Tianzhi Chen, Shunxin Wang, Yixuan Yao, Jinghui Yang, Fan Zhao, Tingting Li, Haitao Wang, Xiaosheng Zhang, Jinlong Zhang, Qiuyue Liu, Shuai Gao, Yuchang Yao, Jianyong Han, Suying Cao   +28 more
wiley   +1 more source

Challenges and resistance mechanisms to EGFR targeted therapies in head and neck cancers and breast cancer: Insights into RTK dependent and independent mechanisms. [PDF]

Oncotarget
Shyamsunder S, Lu Z, Takiar V, Waltz SE.
europepmc   +1 more source

Mediation by the Protein-tyrosine Kinase Tec of Signaling between the B Cell Antigen Receptor and Dok-1 [PDF]

, 2000
Koji Yoshida, Yoshihiro Yamashita, Akira Miyazato, Ken‐ichi Ohya, Akira Kitanaka, Uichi Ikeda, Kazuyuki Shimada, Takeo Yamanaka, Keiya Ozawa, Hiroyuki Mano   +9 more
openalex   +1 more source

Human iPSC‐Derived Mononuclear Phagocytes Improve Cognition and Neural Health across Multiple Mouse Models of Aging and Alzheimer's Disease

Advanced Science, EarlyView.
Short‐term intravenous treatments with iPSC‐derived mononuclear phagocytes (iMPs) improve cognitive decline and neural health in two mouse models of aging and in the 5xFAD mouse model of Alzheimer's disease. iMPs reduce levels of serum amyloid proteins that increase in aging and improve the health of hippocampal microglia and mossy cells.
V. Alexandra Moser, Luz Jovita Dimas‐Harms, Rachel M. Lipman, Jake Inzalaco, Shaughn Bell, Michelle Alcantara, Erikha Valenzuela, George Lawless, Simion Kreimer, Sarah J. Parker, Helen S. Goodridge, Clive N. Svendsen   +11 more
wiley   +1 more source

Identification of an Atypical Grb2 Carboxyl-terminal SH3 Domain Binding Site in Gab Docking Proteins Reveals Grb2-dependent and -independent Recruitment of Gab1 to Receptor Tyrosine Kinases [PDF]

, 2000
Lisa Lock, Isabelle Royal, Monica A. Naujokas, Morag Park   +3 more
openalex   +1 more source

Integrative Omics Reveals Glutamine Catabolism‐Driven Apoptotic Suppression in Monocytes upon Mechanical Unloading

Advanced Science, EarlyView.
This research integrated multi‐omics analysis of bone tissue from HLU and control mice revealed that mechanical unloading suppresses intrinsic apoptosis and augments glutamine (Gln) catabolism in osteoclast lineage cells. The findings highlight pivotal roles for SLC1A5‐mediated Gln metabolism and XIAP/Diablo axis‐mediated apoptosis suppression.
Yi Ding, Fan Tong, Mingqiu Liu, Pin Yang, Jing Zeng, Yinghua Wei, Chunlin Li, Dong Li, Cheng Chang, Yangjun Zhang, Shaoqiong Yi, Fan Hu, Wenjie Shu, Lingqiang Zhang, Chun‐Ping Cui   +14 more
wiley   +1 more source

Targeting kinases that regulate programmed cell death: a new therapeutic strategy for breast cancer. [PDF]

J Transl Med
Hong Y, He J, Deng D, Liu Q, Zu X, Shen Y.   +5 more
europepmc   +1 more source

Vav3 Mediates Receptor Protein Tyrosine Kinase Signaling, Regulates GTPase Activity, Modulates Cell Morphology, and Induces Cell Transformation [PDF]

, 2000
Liyu Zeng, Perminder S. Sachdev, LunBiao Yan, Joseph L.‐K. Chan, Thomas Trenkle, Michael McClelland, John Welsh, Lu–Hai Wang   +7 more
openalex   +1 more source