Results 201 to 210 of about 181,056 (261)

Nerve Growth Factor is Sufficient to Cause Multiple Osteoarthritis‐Relevant Pathologic Features in Naïve Murine Knee Joints

Arthritis &Rheumatology, EarlyView.
Objective Nerve growth factor (NGF), a key mediator of pain, is increased in osteoarthritic (OA) joints. Antibodies against NGF show analgesic effects in painful knee OA, but clinical development was stopped because of side effects in the joints. Knowledge about the biologic effects of NGF on joint tissues is limited. Therefore, we explored the effects
Alia M. Obeidat, Michael D. Newton, Jun Li, Baofeng Hu, Shingo Ishihara, Lindsey Lammlin, Lucas M. Junginger, Easton C. Farrell, Lai Wang, Frank C. Ko, Richard J. Miller, Carla R. Scanzello, Tristan Maerz, Rachel E. Miller, Anne‐Marie Malfait   +14 more
wiley   +1 more source

Deciphering O‑GlcNAc-Dependent Signaling Via Integrated Proteomics and Phosphoproteomics. [PDF]

ACS Omega
Wu C, Hou C, Wang X, Peng Y, Lin Y, Byers SW, Pei H, Ma J.   +7 more
europepmc   +1 more source

Expert Perspectives: Defining and Managing Progressive Pulmonary Fibrosis in Systemic Sclerosis

Arthritis &Rheumatology, EarlyView.
Systemic sclerosis–associated interstitial lung disease (SSc‐ILD) is one of the leading causes of morbidity and mortality in SSc, affecting up to three‐quarters of patients. The disease course is highly heterogeneous, ranging from indolent, nonprogressive forms to rapidly progressive pulmonary fibrosis (PPF).
Devis Benfaremo, Dinesh Khanna, Corrado Campochiaro, Vincent Cottin, Fabrizio Luppi, Marco Matucci‐Cerinic, Gianluca Moroncini, Yannick Allanore   +7 more
wiley   +1 more source

Protein kinase-related tumors in the pediatric population : Updated review on an emerging group with emphasis on the more rarely involved kinases. [PDF]

Pathologie (Heidelb)
Flucke U, Versleijen-Jonkers YMH, Mentzel T, Mueller AM, Hiemcke-Jiwa LS, Alaggio R.   +5 more
europepmc   +1 more source

Elevated Protein Tyrosine Phosphatase Kappa Expression Is Associated With Disease Progression and Poor Prognosis of Pancreatic Cancer. [PDF]

Cancer Diagn Progn
Fang Z, Liu X, Tian X, Al-Sarireh B, Hao C, Jiang WG, Ye L.   +6 more
europepmc   +1 more source

RNA polymerase II: the elephant in the room. [PDF]

Trends Genet
Henikoff S, Hahn S.
europepmc   +1 more source

Targeting DYRKs in Cardiovascular Diseases: From Biological Mechanisms to Therapeutic Translation. [PDF]

Int J Mol Sci
Jiang L, Peng S, Ma J, Liu T, Long X, Li L, Wu H.   +6 more
europepmc   +1 more source

Molecularly Targeted Therapies in Oncology: Mechanisms, Resistance, and Combination Strategies. [PDF]

Molecules
Giercuszkiewicz-Haśnik K, Morak-Młodawska B, Jeleń M.   +2 more
europepmc   +1 more source

A Novel Tyrosine Kinase Axis in Innate Immune Signaling. [PDF]

Viruses
Das S, Sengupta P, Veleeparambil M, Chattopadhyay S.   +3 more
europepmc   +1 more source