Results 201 to 210 of about 396,884 (345)

3D Brain Vascular Niche Model Captures Glioblastoma Infiltration, Dormancy, and Gene Signatures

Advanced Science, EarlyView.
This study developed a 3D brain vascular niche model that capture the key features of glioblastoma including perivascular infiltration, gene signature, dormancy and chemo resistance, by comparing 3D model with in vivo condition using identical glioma stem cells.
Vivian K. Lee, Rut Tejero, Nathaniel Silvia, Anirudh Sattiraju, Aarthi Ramakrishnan, Li Shen, Alexandre Wojcinski, Santosh Kesari, Roland H. Friedel, Hongyan Zou, Guohao Dai   +10 more
wiley   +1 more source

Exploring UBASH3A: from immune regulation to autoimmune diseases. [PDF]

J Transl Med
Zhou M, Sun F, Zhao Z, Qian H, Zhang Y, Song Y.   +5 more
europepmc   +1 more source

Stimulation of the Mitogen-activated Protein Kinase Cascade and Tyrosine Phosphorylation of the Epidermal Growth Factor Receptor by Hepatopoietin [PDF]

, 2000
Yong Li, Ming Li, Guichun Xing, Zhiyuan Hu, Qingming Wang, Chunna Dong, Handong Wei, Fan Guocai, Jizhong Chen, Xiaoming Yang, Shi-Fu Zhao, Huipeng Chen, Kun‐Liang Guan, Chutse Wu, Chenggang Zhang, Fuchu He   +15 more
openalex   +1 more source

The Evolutionary Trajectory and Prognostic Value of GITR+ Tregs Reprogramed by Tumor‐Intrinsic PD‐1/c‐MET Signaling in Pancreatic Cancer

Advanced Science, EarlyView.
In pancreatic ductal adenocarcinoma (PDAC), tumor‐intrinsic PD‐1 signaling activates the MET pathway, leading to the establishment of an immunosuppressive tumor microenvironment (TME). This MET‐driven signaling cascade promotes the selective accumulation of GITR+ regulatory T cells (Tregs), a highly immunosuppressive subset.
Jiande Han, Hanlin Yin, Taochen He, Junyi He, Zhenlai Jiang, Qiangda Chen, Zhihang Xu, Yuqi Xie, Yaolin Xu, Haibo Wang, Wenquan Wang, Wenchuan Wu, Yun Jin, Wenhui Lou, Jun Yu, Ning Pu, Liang Liu   +16 more
wiley   +1 more source

Analysis of the interaction of ZAP-70 and syk protein-tyrosine kinases with the T-cell antigen receptor by plasmon resonance.

, 1995
Jia-Ying Bu, Andréy S. Shaw, Andrew C. Chan   +2 more
openalex   +1 more source

Direct Binding of the Signaling Adapter Protein Grb2 to the Activation Loop Tyrosines on the Nerve Growth Factor Receptor Tyrosine Kinase, TrkA [PDF]

, 2000
James I. MacDonald, Ela A. Gryz, Chris J. Kubu, Joseph M. Verdi, Susan O. Meakin   +4 more
openalex   +1 more source

Receptor protein tyrosine phosphatase alpha activates pp60c‐src and is involved in neuronal differentiation.

EMBO Journal, 1993
J. Hertog, C. Pals, M. Peppelenbosch, L. Tertoolen, S. D. Laat, W. Kruijer   +5 more
semanticscholar   +1 more source

Kindlin Regulates Mechanosensitive Activation and Adhesion Assembly of Integrin beta6

Advanced Science, EarlyView.
Extracellular matrix compliance plays a critical role in the regulation of integrin‐mediated adhesion and cell motility. Here, it is reported that strengthening the kindlin2‐integrin β6 interaction overcomes the dependence on extracellular substrate stiffness and promotes integrin β6‐mediated cell migration.
Wan Ning Lee, Jiamin Li, Nan‐Peng Chen, Cheng‐han Yu   +3 more
wiley   +1 more source

Curcumenol Inhibits Mast Cells Activation in Ovalbumin-Induced Anaphylaxis Model Mice through Modulation of the Fc Epsilon Receptor I Signaling Pathway. [PDF]

Biomol Ther (Seoul)
Kang YM, Shim KS, Chae SW, Bok SH, Park DH, Kim K, Lee B, Park SY, Kim T, Kim KM.   +9 more
europepmc   +1 more source

Co-ordination of the expression of the protein tyrosine kinase p56lck with the pre-T cell receptor during thymocyte development [PDF]

, 2000
Jennifer Buckland, Daniel J. Pennington, Ludovica Bruno, Michael J. Owen   +3 more
openalex   +1 more source