Results 201 to 210 of about 514,942 (384)

Single‐Cell Analysis Clarifies Pathological Heterogeneity in Tenosynovial Giant Cell Tumor and Identifies Biomarkers for Predicting Disease Recurrence

Advanced Science, EarlyView.
MP3 tumor cells, a specific subpopulation of tumor cells in D‐TGCT, regulated the differentiation of CD34+ Fbs into MMP3+ Fbs and APOE+ Fbs through COL6A3 − (ITGAV + ITGB8) interaction. APOE+ Fbs activated IL‐1B+CCL20+ Mφs through the CXCL12/CXCR4 axis. IL‐1B+CCL20+ Mφs and MMP3+ Fbs participated in the local invasion of D‐TGCT.
Yubin Xie, Chen Chen, Fei Wu, Yiman Peng, Jing Su, Yang Zhao, Hongjie Huang, Zhong Alan Li, Yin Pei, Wencui Li, Yi He, Tianchen Xue, Chenxi Cao, Sui Peng, Xin Zhang, Weidong Song   +15 more
wiley   +1 more source

Tyrosine kinase as therapeutic target of neurodegenerative disorders

Brain Disorders
Classes of hereditary and sporadic illnesses known as neurodegenerative diseases are linked to gradual nervous system malfunction and neuronal death. Protein kinases are an increasingly popular class of pharmacological targets for disorders affecting ...
Dipanjan Karati, Dileep Kumar
doaj  

The Role of Tyrosine Kinase in Beauty and Skincare: A Comprehensive Review. [PDF]

J Cosmet Dermatol
Li Z.
europepmc   +1 more source

Isolation and characterization of a novel receptor-type protein tyrosine kinase (hek) from a human pre-B cell line.

, 1992
Andy Boyd, L.D. Ward, Ian P. Wicks, Richard J. Simpson, Evelyn Salvaris, Andrew F. Wilks, K Welch, Maureen Loudovaris, Steven Rockman, Inny Busmanis   +9 more
openalex   +1 more source

Post‐Translational Modifications in Cilia and Ciliopathies

Advanced Science, EarlyView.
This review synthesizes current understanding of post‐translational modifications (PTMs) in ciliary proteins and emphasizes their roles in ciliary formation, homeostasis, and signaling. This review also discusses the implication of PTM dysregulation in ciliopathies and explores therapeutic strategies targeting PTM‐modifying enzymes.
Jie Ran, Jun Zhou
wiley   +1 more source

Cracking the Kinase Code: Urinary Biomarkers as Early Alarms for AAA Rupture-A Pilot Study. [PDF]

J Clin Med
Östling EM, Baltrunas T, Grootenboer N, Urbonavicius S.   +3 more
europepmc   +1 more source

Protein kinase C isoforms β 1 and β 2 inhibit the tyrosine kinase activity of the insulin receptor [PDF]

, 1997
Birgit Bossenmaier, Luitgard Mosthaf, Harald Mischak, A. Ullrich, Hans‐Ulrich Häring   +4 more
openalex   +1 more source

Comparative Analysis of Clinical Outcomes and Financial Aspects of Phototherapies and Immunotherapy for Cancer

Advanced Science, EarlyView.
This review compares clinical outcomes, translational progress, and global funding trends across cancer phototherapies—photodynamic, photothermal, and photoimmunotherapy—and conventional immunotherapy. It highlights differences in treatment efficacy, clinical trial status, financial investment, and regulatory challenges, providing a comprehensive ...
Deepak S. Chauhan, Kun Shao, Roopa Hebbandi Nanjundappa, Daniel‐Jiajun Yu, Marianne Stanford, Huile Gao, Channakeshava Sokke Umeshappa   +6 more
wiley   +1 more source

Innovative Approaches in Cancer Treatment: Emphasizing the Role of Nanomaterials in Tyrosine Kinase Inhibition. [PDF]

Pharmaceutics
Kurillová A, Kvítek L, Panáček A.
europepmc   +1 more source

Cell-contact-dependent signalling in axon growth and guidance: Eph receptor tyrosine kinases and receptor protein tyrosine phosphatase β

, 1998
Sacha J. Holland, Elior Peles, Tony Pawson, Joseph Schlessinger   +3 more
openalex   +1 more source