Results 91 to 100 of about 334,561 (215)

ImmunoPET Targeting Receptor Tyrosine Kinase: Clinical Applications. [PDF]

Cancers (Basel), 2023
Linguanti F, Abenavoli EM, Calabretta R, Berti V, Lopci E.   +4 more
europepmc   +1 more source

PROS1‐MERTK Axis Drives Tumor Microenvironment Crosstalk and Progression in Papillary Thyroid Microcarcinoma

Advanced Science, EarlyView.
Identifying biomarkers associated with PTC, particularly those related to PTMC progression, is crucial for precise risk stratification and treatment planning. This study utilized single‐cell RNA sequencing on 19 surgical tissue specimens, confirmed PROS1/MERTK axis as a critical component of the cellular microenvironment and a key regulatory mechanism ...
Wenqian Zhang, Ye Zhang, Zhu Liu, Zhiyuan Wang, Huaqin Wang, Xiaoyu Ji, Hongyue Su, Fan Yang, Lirong Yan, Ying Xu, Hao Zhang, Wei Sun   +11 more
wiley   +1 more source

Identification of chicken embryo kinase 5, a developmentally regulated receptor-type tyrosine kinase of the Eph family. [PDF]

, 1991
Elena B. Pasquale
openalex   +1 more source

A pharmacovigilance study of thromboembolism events associated with vascular endothelial growth factor receptor tyrosine kinase inhibitors based on FAERS database. [PDF]

Sci Rep
Tang Z, Song H, Pan L, Zhang M, Li S, Li W, Chen W, Wang X.   +7 more
europepmc   +1 more source

PTPN2 Inhibition Disrupts Mitochondrial Renewal and Blocks TFRC‐Mediated Mitophagy to Exert Anti‐Tumor Activities in ALK‐Positive Anaplastic Large Cell Lymphoma

Advanced Science, EarlyView.
CRISPR/Cas9 screening reveals PTPN2 as essential for ALK+ ALCL survival. PTPN2 regulates TFRC to promote PINK1‐PRKN mitophagy. Oral PTPN2 inhibitor ABBV‐CLS‐484 disrupts mitochondrial renewal and blocks TFRC‐mediated mitophagy to exert anti‐tumor activities, supporting clinical development for ALK+ ALCL.
Wei‐Ting Wang, Zi‐Wen Duan, Tong‐Yao Xing, Wei Hua, Kai‐Xing Du, Chun‐Yu Shang, Yi‐Fan Wu, Li Wang, Jian‐Yong Li, Rui Gao, Jin‐Hua Liang, Wei Xu   +11 more
wiley   +1 more source

Tyrosine kinase activity coupled to the high-affinity nerve growth factor-receptor complex.

, 1991
Susan O. Meakin, E.M. Shooter
openalex   +1 more source

Down-regulation of cellular platelet-derived growth factor receptors induced by an activated neu receptor tyrosine kinase. [PDF]

, 1991
Laura Lehtola, Monica Nistér, Erkki Hölttä, Bengt Westermark, Kari Alitalo   +4 more
openalex   +1 more source

Longitudinal pharmacogenomic analysis of refractory lung cancer to identify therapeutic candidates for epidermal growth factor receptor-tyrosine kinase inhibitor resistance subclones. [PDF]

Exp Mol Med
Yu N, Hwang M, Ahn BC, Lee Y, Hong S, Sim H, Song BR, Kim S, Park C, Han JY.   +9 more
europepmc   +1 more source

Piezoelectric Biomaterials for Bone Regeneration: Roadmap from Dipole to Osteogenesis

Advanced Science, EarlyView.
Piezoelectric biomaterials convert mechanical forces into electrical signals, offering novel strategies to restore and modulate bone microenvironments for tissue engineering. This review examines molecular dipole origins, spatial arrangements, and pseudo‐piezoelectric mechanisms and highlights dipole‐engineering techniques for osteogenesis regulation ...
Xiyao Ni, Yufei Cui, Mojtaba Salehi, Mui Ling Sharon Nai, Kun Zhou, Cian Vyas, Boyang Huang, Paulo Bartolo   +7 more
wiley   +1 more source

Multiple tyrosine protein kinases in rat hippocampalneurons: isolation of Ptk-3, a receptor expressed in proliferative zones of thedeveloping brain.

, 1994
Marina P. Sánchez, Peter Tapley, Sarbjit S. Saini, Baoyu He, Daniel Pulido, Mariano Barbacid   +5 more
openalex   +1 more source