Results 241 to 250 of about 940,834 (307)
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The FASEB Journal, 1992
A major process through which environmental information is transmitted into cells is via activation of protein tyrosine kinases. Receptor tyrosine kinases contain extracellular ligand recognition, single membrane spanning, and cytoplasmic protein tyrosine kinase domains.
Deborah L. Cadena, Gordon N. Gill
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A major process through which environmental information is transmitted into cells is via activation of protein tyrosine kinases. Receptor tyrosine kinases contain extracellular ligand recognition, single membrane spanning, and cytoplasmic protein tyrosine kinase domains.
Deborah L. Cadena, Gordon N. Gill
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Receptor Tyrosine Kinase Inhibitors
2015Receptor tyrosine kinases (RTKs) are a diverse group of transmembrane proteins involved in signal transduction. Their function in many cell types is to drive a wide variety of cellular functions, including growth, differentiation and angiogenesis, by transducing growth factor signals from the external milieu to intracellular processes. In malignancies,
Antony M. Latham +2 more
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Receptor Tyrosine Kinases and Anticancer Therapy
Current Pharmaceutical Design, 2005Receptor and non-receptor protein tyrosine kinases (PTKs) are essential enzymes in cellular signaling processes and signal transduction pathways that regulate cell growth, differentiation, migration and metabolism by catalyzing protein phosphorylation and dephosphorylation.
Medinger, Michael, Drevs, Joachim
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Receptor tyrosine kinases and their targets
Current Opinion in Genetics & Development, 1994One of the ways in which higher eukaryotes receive messages from the environment is via cell surface receptor tyrosine kinases. These are transmembrane proteins with an extracellular binding domain that specifies the growth factor with which it will interact, and an intracellular domain that encodes the tyrosine kinase.
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Surgical Oncology Clinics of North America, 2001
The last two decades have witnessed significant progress in the understanding of the basic mechanisms underlying tumor growth and metastasis. Receptor tyrosine kinases play a central role in cell proliferation and differentiation, cell survival, cell motility, invasion, and angiogenesis, all of which contribute to tumor progression.
Morag Park, Louie Lamorte
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The last two decades have witnessed significant progress in the understanding of the basic mechanisms underlying tumor growth and metastasis. Receptor tyrosine kinases play a central role in cell proliferation and differentiation, cell survival, cell motility, invasion, and angiogenesis, all of which contribute to tumor progression.
Morag Park, Louie Lamorte
openaire +3 more sources