Results 81 to 90 of about 334,561 (215)

Understanding miR‐200c: an Important Player in Resistance to Cancer Treatment

Advanced Therapeutics, EarlyView.
How can one microRNA alter cancer's response to therapy? miR‐200c plays a central role in therapeutic resistance by modulating epithelial‐mesenchymal transition, apoptosis, cancer stemness features, and drug efflux. This review outlines the context‐dependent functions of miR‐200c in various cancers and highlights its potential as both a biomarker and a
Fatma Sanli, Omer Faruk Karatas
wiley   +1 more source

Expression of isoforms of the human receptor tyrosine kinase c-kit in leukemic cell lines and acute myeloid leukemia [PDF]

, 1993
PS Crosier, ST Ricciardi, L. R. Hall, MR Vitas, SC Clark, KE Crosier   +5 more
openalex   +1 more source

A novel TRKB-activating internal tandem duplication characterizes a new mechanism of receptor tyrosine kinase activation. [PDF]

NPJ Precis Oncol
Brown LM, Tax G, Acera Mateos P, de Weck A, Foresto S, Robertson T, Jalud F, Ajuyah P, Barahona P, Mao J, Dolman MEM, Wong M, Mayoh C, Cowley MJ, Lau LMS, Sadras T, Ekert PG.   +16 more
europepmc   +1 more source

NAD+‐Boosters Improve Mitochondria Quality Control In Parkinson's Disease Models Via Mitochondrial UPR

Advanced Science, EarlyView.
Treatment of MPTP‐incubated cells with NAD+‐boosters increase the UPRmt/mitophagy‐related mitochondria quality control (MQC). Disturbed plasma UPRmt‐mitophagy‐mediated MQC profiles in PD patient samples. NMN inhibits motor deficit and forestalls neuropathology phenotypes of PD mice, which is required the atf4‐medicated UPRmt pathway.
Shuoting Zhou, Xi Xiong, Jialong Hou, Qi Duan, Yi Zheng, Tao Jiang, Jiani Huang, Haijun He, Jiaxue Xu, Keke Chen, Wenwen Wang, Jinlai Cai, Jingjing Qian, Huijun Chen, Weihong Song, XinShi Wang, Chenglong Xie   +16 more
wiley   +1 more source

CD5 acts as a tyrosine kinase substrate within a receptor complex comprising T-cell receptor zeta chain/CD3 and protein-tyrosine kinases p56lck and p59fyn.

, 1992
Karl Burgess, Masahiro Yamamoto, Kartik Prasad, Christopher E. Rudd   +3 more
openalex   +1 more source

Interleukin 7 receptor functions by recruiting the tyrosine kinase p59fyn through a segment of its cytoplasmic tail. [PDF]

, 1992
Ashok R. Venkitaraman, Rachel J. Cowling
openalex   +1 more source

Cellular Receptor Tyrosine Kinase Signaling Plays Important Roles in SARS-CoV-2 Infection. [PDF]

Pathogens
Sanchez S, Flannery BH, Murphy H, Huang Q, Ly H, Liang Y.   +5 more
europepmc   +1 more source

LincNEAT1 Encoded‐NEAT1‐31 Promotes Phagocytosis by Directly Activating the Aurora‐A–PI3K–AKT Pathway

Advanced Science, EarlyView.
LincNEAT1 Encoded‐NEAT1‐31 micropeptide directly binds with Aurora‐A and enhanced AKT pathways to pormotes phagocytosis against multi cancer cells. Abstract Macrophages play vital roles in innate and adaptive immunity, and their essential functions are mediated by phagocytosis and antigen presentation.
Jie Li, Jing Zhang, Xixi Li, Xin Liu, Bo Zeng, Jiayue Luo, Huijin Wang, Hanbing Zhang, Xinya Gao   +8 more
wiley   +1 more source

Molecular cloning of human Syk. A B cell protein-tyrosine kinase associated with the surface immunoglobulin M-B cell receptor complex.

, 1994
Che‐Leung Law, Sidorenko Sp, K A Chandran, Kay Draves, Andrew C. Chan, Arthur Weiss, Susanne Edelhoff, Christine M. Distèche, Edward A. Clark   +8 more
openalex   +1 more source

Current management of neurotrophic receptor tyrosine kinase fusion-positive sarcoma: an updated review. [PDF]

Jpn J Clin Oncol
Kubota Y, Kawano M, Iwasaki T, Itonaga I, Kaku N, Ozaki T, Tanaka K.   +6 more
europepmc   +1 more source