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Hypothalamic alpha adrenergic receptors in cardiovascular regulation
Neuropharmacology, 1974Abstract Stereotaxic injection of noradrenaline (3–100 nmol) into the anterior hypothalamicpreoptic region of pentobarbital anaesthetized rats induced a fall in blood pressure and heart rate. The size of the effect was related to the size of the dose.
J.M. van Rossum +3 more
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Alpha-2 Adrenergic Receptor Agonists
2014Alpha-2 adrenergic receptor agonists include clonidine, guanfacine, guanabenz, methyldopa, rilmenidine, and moxonidine. These are centrally active antihypertensive drugs.
Esen Özkaya +1 more
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Regulation of alpha-2 Adrenergic Receptors
1988In this chapter, we will review available literature (as of January, 1986) on the regulation of expression of alpha-2 adrenergic receptors. We have somewhat arbitrarily divided regulation of alpha-2 adrenergic receptors into ”physiologic,” ”pharmacologic,” and ”disease-related” changes in receptor expression.
Paul A. Insel, Harvey J. Motulsky
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Agonist Interactions with α-Adrenergic Receptors
Journal of Cardiovascular Pharmacology, 1982alpha-Adrenergic receptors have been grouped into two major subtypes, termed alpha 1- and alpha 2-receptors. Radioligand binding techniques have been utilized to measure the number of alpha 1- and alpha 2-receptors in a variety of tissues. [3H]Dihydroergocryptine labels the entire alpha-receptor population; the alpha-receptor subtypes may be delineated
Robert J. Lefkowitz, Brian B. Hoffman
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Alpha-adrenergic receptors and coronary vasospasm
1984Stimulation of coronary alpha-adrenergic receptors has been repeatedly implicated as a mechanism potentially responsible for coronary spasm. This hypothesis is certainly supported by the experimental observation that coronary arteries are densely innervated with sympathetic fibres and that reflex and pharmacological stimulation of alpha-adrenergic ...
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Adrenergic Alpha- and Beta-receptors in the Mouse Iris
Nature, 1965IN the course of comprehensive studies of the mechanism of sympathetic function using the mouse iris as a working model we have demonstrated adrenergic α- and β-receptors and determined their dynamic properties under the influence of pharmacological agents.
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Alpha-adrenergic receptors and blood pressure control
The American Journal of Cardiology, 1986Alpha-adrenergic receptors play an important role in the regulation of blood pressure (BP). There are 2 principal types of alpha receptors, alpha 1 and alpha 2, and both participate in circulatory control. Alpha 1 receptors are the classic postsynaptic alpha receptors and are found on vascular smooth muscle.
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Regulation of alpha-1 Adrenergic Receptors
1987Catecholamines modulate a wide variety of important physiological processes, alpha-1 Adrenergic receptors play a major role in transducing many of the actions of catecholamines. A particularly prominent action of alpha-1 adrenergic receptors is the promotion of vasoconstriction in a range of vascular beds.
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ALPHA-ADRENERGIC RECEPTORS IN HUMAN OMENTUM?
The Lancet, 1969Suad Efendic, Jan Östman
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