Results 1 to 10 of about 260,930 (256)

Targeting of beta adrenergic receptors results in therapeutic efficacy against models of hemangioendothelioma and angiosarcoma.

PLoS ONE, 2013
Therapeutic targeting of the beta-adrenergic receptors has recently shown remarkable efficacy in the treatment of benign vascular tumors such as infantile hemangiomas.
Jessica M Stiles, Clarissa Amaya, Steven Rains, Dolores Diaz, Robert Pham, James Battiste, Jaime F Modiano, Victor Kokta, Laura E Boucheron, Dianne C Mitchell, Brad A Bryan   +10 more
doaj   +2 more sources

Dissecting Beta-Adrenergic Receptors

JACC: Basic to Translational Science, 2023
J. David Port, PhD
doaj   +2 more sources

Receptor-mediated enhancement of beta adrenergic drug activity by ascorbate in vitro and in vivo. [PDF]

PLoS ONE, 2010
RATIONALE: Previous in vitro research demonstrated that ascorbate enhances potency and duration of activity of agonists binding to alpha 1 adrenergic and histamine receptors.
Patrick F Dillon, Robert Root-Bernstein, N Edward Robinson, William M Abraham, Catherine Berney   +4 more
doaj   +1 more source

Identifying Ligand Binding Conformations of the β2-Adrenergic Receptor by Using Its Agonists as Computational Probes [PDF]

, 2011
Recently available G-protein coupled receptor (GPCR) structures and biophysical studies suggest that the difference between the effects of various agonists and antagonists cannot be explained by single structures alone, but rather that the conformational
Ashley M. Buckle, B Isin, B Isin, B Isin, Basak Isin, BK Kobilka, BK Kobilka, C Gales, CD Strader, CD Strader, CD Strader, DL Farrens, DM Rosenbaum, DM Rosenbaum, DS Han, E Reiter, FZ Chung, G Liapakis, G Liapakis, G Swaminath, G Swaminath, Guillermina Estiu, GV Paolini, HW Choe, I Bahar, JA Javitch, JC Phillips, JE Olsson, JJ Liu, JP Overington, K Palczewski, K Wieland, KA Reynolds, L Shi, LM Luttrell, LS Barak, M Arakawa, M Azzi, MA Yildirim, MP Bokoch, MS Johnson, O Fritze, Olaf Wiest, P Ghanouni, PG Strange, R Nygaard, R Seifert, RA Friesner, RA Friesner, RO Dror, S Ahuja, S Bhattacharya, S Ludeke, SA Green, SG Rasmussen, SG Rasmussen, SG Rasmussen, T Palanche, TD Romo, U Gether, V Cherezov, X Deupi, X Yao, X Zhang, Zoltán N. Oltvai   +64 more
core   +10 more sources

Alpha and beta adrenergic receptors modulate keratinocyte migration.

PLoS ONE, 2021
Keratinocyte migration into skin wounds is the step of the healing process that correlates with the wound closure rate. Keratinocyte migration, and wound epithelialization are decreased when beta 2-adrenergic receptors (B2AR) are activated by 1 μM ...
Hsin-Ya Yang, Pieter Steenhuis, Aaron M Glucksman, Zhanna Gurenko, Thi Dinh La, R Rivkah Isseroff   +5 more
doaj   +1 more source

Beta Adrenergic Receptors in Keratinocytes [PDF]

Dermatologic Clinics, 2007
Beta2 adrenergic receptors were identified in keratinocytes more than 30 years ago, but their function in the epidermis continues to be elucidated. Abnormalities in their expression, signaling pathway, or in the generation of endogenous catecholamine agonists by keratinocytes have been implicated in the pathogenesis of cutaneous diseases such as atopic
Raja K, Sivamani, Susanne T, Lam, R Rivkah, Isseroff   +2 more
openaire   +2 more sources

THE PRINCIPLES OF USING ESMOLOL IN THE PRACTICE OF AN ANESTHESIOLOGIST AND AN INTENSIVE CARE PHYSICIAN

Клінічна та профілактична медицина, 2021
Aim of the study: to analyze the problem of using the beta-1-blocker esmolol for anesthetic management and intensive care from the sources of the modern available literature. Materials and methods. Bibliosemantic, comparative and systems analysis. The
V. I. Cherniy, T. V. Chernii, N.V. Shestak   +2 more
doaj   +1 more source

β2-adrenergic agonists modulate TNF-α induced astrocytic inflammatory gene expression and brain inflammatory cell populations [PDF]

, 2014
Background: The NF-kappa B signaling pathway orchestrates many of the intricate aspects of neuroinflammation. Astrocytic beta(2)-adrenergic receptors have emerged as potential regulators in central nervous system inflammation and are potential targets ...
Aerts, Joeri L, De Keyser, Jacques, Demol, Frauke, Gerlo, Sarah, Laureys, Guy, Spooren, Anneleen   +5 more
core   +3 more sources

Beta-1 and not beta-3-adrenergic receptors may be the primary regulator of human brown adipocyte metabolism.

Journal of Clinical Endocrinology and Metabolism, 2019
PURPOSE Brown adipose tissue (BAT) activation in humans has gained interest as a potential target for treatment of obesity and insulin resistance. In rodents, BAT is primarily induced through beta-3-adrenergic receptor (ADRB3) stimulation, whereas the ...
M. J. Riis-Vestergaard, B. Richelsen, J. Bruun, Wei Li, J. Hansen, S. Pedersen   +5 more
semanticscholar   +1 more source

Studies of membrane fluidity and heart contractile force in Trypanosoma cruzi infected mice

Memorias do Instituto Oswaldo Cruz, 2004
In Chagas disease serious cardiac dysfunction can appear. We specifically studied the cardiac function by evaluating: ventricle contractile force and norepinephrine response, affinity and density of beta-adrenergic receptors, dynamic properties of ...
Julio E Enders, A Ruth Fernández, Héctor W Rivarola, Patricia A Paglini, José A Palma   +4 more
doaj   +1 more source