Results 1 to 10 of about 92,638 (313)

The Role of Beta-Adrenergic Receptors in Depression and Resilience

open access: yesBiomedicines, 2022
Norepinephrine is a catecholamine neurotransmitter that has been extensively implicated in the neurobiology of major depressive disorder (MDD). An accumulating body of evidence indicates that investigations into the action of norepinephrine at the ...
Hongxing Zhang   +3 more
doaj   +3 more sources

Receptor-mediated enhancement of beta adrenergic drug activity by ascorbate in vitro and in vivo. [PDF]

open access: yesPLoS ONE, 2010
RATIONALE: Previous in vitro research demonstrated that ascorbate enhances potency and duration of activity of agonists binding to alpha 1 adrenergic and histamine receptors.
Patrick F Dillon   +4 more
doaj   +1 more source

Beta Adrenergic Receptors in Keratinocytes [PDF]

open access: yesDermatologic Clinics, 2007
Beta2 adrenergic receptors were identified in keratinocytes more than 30 years ago, but their function in the epidermis continues to be elucidated. Abnormalities in their expression, signaling pathway, or in the generation of endogenous catecholamine agonists by keratinocytes have been implicated in the pathogenesis of cutaneous diseases such as atopic
Susanne T. Lam   +3 more
openaire   +3 more sources

Alpha and beta adrenergic receptors modulate keratinocyte migration.

open access: yesPLoS ONE, 2021
Keratinocyte migration into skin wounds is the step of the healing process that correlates with the wound closure rate. Keratinocyte migration, and wound epithelialization are decreased when beta 2-adrenergic receptors (B2AR) are activated by 1 μM ...
Hsin-Ya Yang   +5 more
doaj   +1 more source

THE PRINCIPLES OF USING ESMOLOL IN THE PRACTICE OF AN ANESTHESIOLOGIST AND AN INTENSIVE CARE PHYSICIAN

open access: yesКлінічна та профілактична медицина, 2021
Aim of the study: to analyze the problem of using the beta-1-blocker esmolol for anesthetic management and intensive care from the sources of the modern available literature. Materials and methods. Bibliosemantic, comparative and systems analysis. The
V. I. Cherniy   +2 more
doaj   +1 more source

Studies of membrane fluidity and heart contractile force in Trypanosoma cruzi infected mice

open access: yesMemorias do Instituto Oswaldo Cruz, 2004
In Chagas disease serious cardiac dysfunction can appear. We specifically studied the cardiac function by evaluating: ventricle contractile force and norepinephrine response, affinity and density of beta-adrenergic receptors, dynamic properties of ...
Julio E Enders   +4 more
doaj   +1 more source

Targeting of beta adrenergic receptors results in therapeutic efficacy against models of hemangioendothelioma and angiosarcoma.

open access: yesPLoS ONE, 2013
Therapeutic targeting of the beta-adrenergic receptors has recently shown remarkable efficacy in the treatment of benign vascular tumors such as infantile hemangiomas.
Jessica M Stiles   +10 more
doaj   +1 more source

Efficacy of beta 1-adrenergic receptors is lower than that of beta 2-adrenergic receptors. [PDF]

open access: yesProceedings of the National Academy of Sciences, 1993
We investigated the relative activity at which fully occupied human beta 1- and beta 2-adrenergic receptors (beta 1AR and beta 2AR) activate the stimulatory G protein (Gs)/adenylyl cyclase (AC) system in isolated membranes. The receptors were cloned and coexpressed in permanent cell lines at beta 1/beta 2 ratios that varied from 1:2 to 3:1 and at total
Xi Zhu   +4 more
openaire   +3 more sources

An assay for beta-adrenergic receptors in isolated human fat cells.

open access: yesJournal of Lipid Research, 1982
The beta-adrenergic receptors have been characterized in isolated human adipocytes using a potent beta-adrenergic antagonist (-)-[3H]dihydroalprenolol.
P Engfeldt   +3 more
doaj   +1 more source

Preponderance of alpha 2- over beta 1-adrenergic receptor sites in human fat cells is not predictive of the lipolytic effect of physiological catecholamines

open access: yesJournal of Lipid Research, 1983
Adrenergic control of human fat cell lipolysis is mediated by two kinds of receptor sites that are simultaneously stimulated by physiological amines. To establish a correlation between the binding characteristics of the receptor and biological functions,
M Lafontan, M Berlan, A Villeneuve
doaj   +1 more source

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