Results 151 to 160 of about 1,323,755 (303)

Bioengineered microbiotic levodopa therapy improves cognition and reduces pathology in a rat model of Alzheimer's disease

British Journal of Pharmacology, EarlyView.
Background and Purpose Degeneration of the pontine noradrenergic and midbrain dopaminergic systems contributes to cognitive‐behavioural disturbances during the prodromal stages of Alzheimer's disease (AD). We developed a genetically engineered, programmable probiotic Escherichia coli Nissle 1917 strain (EcNrhaL‐DOPA) capable of producing L‐3,4 ...
Mona Abdelhamid, Piyush Padhi, Mahsa Gifani, John S. Beck, Jacob P. Thomas, Gargi Khadse, Catherine Kudela, Gregory J. Phillips, Anumantha G. Kanthasamy, Scott E. Counts   +9 more
wiley   +1 more source

Screening the Tox21 Compound Library for Chemicals That Stimulate the Adrenergic β1 Receptor. [PDF]

Chem Res Toxicol
Adesina PA, Zhang L, Sukhawanit C, Wood S, Zhao J, Li Z, Sakamuru S, Ferguson SS, Hsieh JH, Reif DM, Huang R, Xia M.   +11 more
europepmc   +1 more source

Psychological Stress Promotes Tumor Growth in Hepatocellular Carcinoma Models Through Myeloid Signaling

Cancer Science, EarlyView.
Psychological stress promotes hepatocellular carcinoma progression through coordinated regulation of macrophages and neutrophils. Noradrenaline activates ADRB2 signaling in intratumoral macrophages, leading to CXCL2 production and neutrophil recruitment.
Keita Ogawa, Takahiro Aoki, Tatsuya Kaneko, Hongxuan Wang, Daiki Shimizu, Daisuke Katsumi, Iori Kojima, Hidekazu Tanaka, Kiwamu Motoyoshi, Ko Ozaki, Katsuhiro Nishimura, Tomohisa Iinuma, Mariko Takami, Shinichiro Motohashi   +13 more
wiley   +1 more source

Influence of adrenergic drugs and volume loading on mean systemic filling pressure in non-septic and septic sheep. [PDF]

Front Med (Lausanne)
Hahn RG.
europepmc   +1 more source

Reassessing Perioperative Management Strategies for Phaeochromocytoma and Paraganglioma Resections

ANZ Journal of Surgery, EarlyView.
Jun Wei Chong, Simon Harper, Stephanie Manning, Rosemary M. Hall   +3 more
wiley   +1 more source

Current Approaches to Support Patients to Withdraw From Image and Performance Enhancing Drugs

Clinical Endocrinology, EarlyView.
ABSTRACT Image and performance‐enhancing drugs (IPEDs) include agents such as androgens, growth hormone, and erythropoietin, which are used to enhance appearance and physical performance. Androgens, also known as anabolic‐androgenic steroids (AAS), are the most used IPEDs worldwide.
Elizabeth Hyams, Bonnie Grant, Richard Quinton, Channa N. Jayasena   +3 more
wiley   +1 more source

Transient acute kidney injury following femoral fracture in mice : the role of sympathetic activation. [PDF]

Bone Joint Res
Oßwald K, Herbst H, Dieterich S, Balmayor ER, Ignatius A, Huber-Lang M, Haffner-Luntzer M, Halbgebauer R.   +7 more
europepmc   +1 more source

Glucocorticoids and HPA axis regulation in the stress–obesity connection: A comprehensive overview of biological, physiological and behavioural dimensions

Clinical Obesity, Volume 15, Issue 2, April 2025.
Summary Chronic stress, characterized by increased long‐term exposure to the glucocorticoid hormone cortisol, is increasingly linked to obesity development. Still, various knowledge gaps persist, including on underlying pathophysiological mechanisms. The aim of the current review is to provide the latest insights on the connection between stress and ...
Robin Lengton, Myrte Schoenmakers, Brenda W. J. H. Penninx, Mariëtte R. Boon, Elisabeth F. C. van Rossum   +4 more
wiley   +1 more source

The neuro-immune axis in cancer: mechanisms of neural regulation of immunity within the tumor microenvironment to promote cancer progression. [PDF]

Front Immunol
Ran Z, Zeng C, Han J, Yu X.
europepmc   +1 more source

The human heart beta-adrenergic receptors. I. Heterogeneity of the binding sites: presence of 50% beta 1- and 50% beta 2-adrenergic receptors.

, 1983
Beta-adrenergic receptors were characterized in a particulate fraction of human auricles obtained from patients operated upon for coronary insufficiency or valvular disease.
De Smet, Jean-Marie, Delhaye, Myriam, De Neef, Philippe, Christophe, Jean, Waelbroeck, Magali, Chatelain, Pierre, Taton, Gérard, Leclerc, Jean Louis, Robberecht, Patrick   +8 more
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