Results 161 to 170 of about 1,323,755 (303)

Effects of 6‐OHDA‐Mediated Chemical Denervation of Sympathetic Axons in Inguinal Subcutaneous White Adipose Tissue

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims White adipose tissue (WAT) innervation by sensory and sympathetic axons contributes to tissue functions, but the consequences of selectively disrupting sympathetic input to WAT remain incompletely defined. Materials and Methods We utilised 6‐hydroxydopamine (6‐OHDA) as a validated approach to achieve bilateral sympathetic denervation of ...
Gilian Gunsch, Gargi Mishra, Magdalena Blaszkiewicz, Erica de Sousa, Jake W. Willows, Katharine W. Alltop, Annemarie Towle, Shawn Collins, Andre Khalil, Isabel F. Snodgrass, Lara Agha, Kiran Prakash, Rashmika Maganuru, Sugasini Dhavamani, John W. Newman, Kristy L. Townsend   +15 more
wiley   +1 more source

Targeting the Neuro-Immune Axis in Next-Generation Oncology: Discovery and Validation of β₂-Adrenergic Blockade to Reverse Ecosystem-Wide Resistance. [PDF]

Oncol Res
Xu H, Lu J, Wang Z, Xu J, Peng S, Chen H, Cao Q, Sun Q, Huang S.   +8 more
europepmc   +1 more source

Antenatal Corticosteroids in Gestational Diabetes: A Systematic Review of Glycemic Response and Management Strategies

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Background Antenatal corticosteroids (ACS) promote foetal lung maturation in pregnancies at risk of preterm birth; however, in gestational diabetes mellitus (GDM), they can exacerbate maternal glycemia and contribute to adverse neonatal outcomes. Clinical guidelines offer limited direction on optimal treatment adjustment.
Alexandra Katz, Aidan Shulkin, Samantha Jacobson, Chella Price, Michael A. Tsoukas, Isabella Albanese, Agnieszka Majdan, Jill Pancer, Ariane Godbout, Kaberi Dasgupta, Anne‐Sophie Brazeau, Tricia Peters   +11 more
wiley   +1 more source

Adipocyte β3-adrenergic receptor signaling attenuates leptin production but is dispensable for fasting induced leptin suppression. [PDF]

Am J Physiol Endocrinol Metab
Heaselgrave SR, Wyler SC, Thomas S, Tinajero A, Galvan M, Mihaila E, Fan R, Fujikawa T, Scherer PE, Elmquist JK.   +9 more
europepmc   +1 more source

Iloperidone treatment mitigates the Juvenile Huntington's Disease phenotype possibly via Sigma‐1 Receptor Modulation

The FEBS Journal, EarlyView.
We investigated the potential of iloperidone as an activator of Sigma‐1 receptor (S1R) neuroprotective function in juvenile Huntington's disease (jHD). We tested iloperidone on cortical neurons differentiated from patient‐derived iPSCs, demonstrating that it acts as a S1R agonist, decreasing apoptosis, huntingtin aggregation, and oxidative stress ...
Ersilia Fornetti, Gaia Galluzzi, Mario Frezzini, Cécile Exertier, Vittorio Brufani, Gianni Colotti, Giancarlo Ruocco, Jessica Rosati, Angelo Luigi Vescovi, Daniele Narzi, Ilaria Genovese, Andrea Ilari   +11 more
wiley   +1 more source

Neural regulation in lung cancer: from mechanisms to new therapeutic perspectives. [PDF]

Clin Exp Med
Zhao J, Han Y, Li Y, Li Y, Sun Y, Bai Y, Chen J, Han C, Yan Y, Zhou C, Liu C.   +10 more
europepmc   +1 more source

Investigating the relaxant effect of aqueous-alcoholic extract of Melissa Officinalis on smooth muscle of isolated rat trachea and its potential mechanisms

مجله دانشگاه علوم پزشکی بیرجند
Background and Aims: Melissa officinalis (M. officinalis) is a well-known medicinal plant with various therapeutic properties such as, antioxidant and anti-inflammatory effects.
Vahideh Sadat Abbasnia, Delaram Eslimi Esfahani, Mohammad Reza Khazdair, Shahrbanoo Oryan, Mohsen Foadoddini   +4 more
doaj  

The Beta-Adrenergic Receptors [PDF]

, 1991
openaire   +1 more source

Adrenergic beta‐receptor blockade in hyperthyroidism. [PDF]

British Journal of Clinical Pharmacology, 1975
openaire   +2 more sources

Adipocyte‐specific NIK depletion enhances energy metabolism and glucose tolerance in mice

The FEBS Journal, EarlyView.
Obesity is associated with reduced energy expenditure and increased hepatic lipid accumulation. This study reveals that loss of NIK in adipocytes stimulates FGF21‐driven expression of thermogenic genes, including UCP1, and mitochondrial uncoupled respiration.
Atakan Ozcan, Caroline Uslucan, Aleyna Kizilyer, Samet Agca, Aylin Karatas, Sanaz Naghizadeh, Bahar Zehra Camurdanoglu Weber, Sukru Anil Dogan, Serkan Kir   +8 more
wiley   +1 more source