Results 171 to 180 of about 1,323,755 (303)

Sex-Dependent S1P-Related Gene Expression in Brown Adipose Tissue Across Exercise and Thermal Conditions. [PDF]

Int J Mol Sci
Ozabrahamyan S, Nirengi S, Vidal P, Baer LA, Stanford KI.   +4 more
europepmc   +1 more source

Tankyrase‐2 regulates adipocyte differentiation through AMPK/mTOR signaling

The FEBS Journal, EarlyView.
Tankyrase 2 (TNKS2), a PARP family member, underpins adipocyte differentiation. TNKS2 controls LKB1 protein level, and consequently, the activity of the mTOR/AMPK system and adipocyte differentiation through a layered process. Pharmacological inhibition of TNKS2 leaves other PARPs and DNA repair active and therefore represents a novel target in ...
Boglarka Rauch, Gyula Ujlaki, Szilard Poliska, Nakayi Murahwa, Patrik Kovacs, Aladar Pettko‐Szandtner, Karen Uray, Peter Bai   +7 more
wiley   +1 more source

Association of Functional <i>ADRB1</i> (rs1801252) and <i>ADRB2</i> (rs1042714) Polymorphisms with Primary Open-Angle Glaucoma in a Saudi Cohort. [PDF]

Int J Mol Sci
Kondkar AA, Sultan T, Azad TA, Osman EA, Almobarak FA, Alsirhy EY, Al-Obeidan SA.   +6 more
europepmc   +1 more source

Directional information flow in human frataxin defines allosteric pathways connecting the hydrophobic core to the iron‐binding ridge

The FEBS Journal, EarlyView.
Human frataxin deficiency causes Friedreich's ataxia, yet how iron‐binding events are communicated across the protein is unclear. Using transfer entropy analysis of molecular dynamics simulations, we identify buried hydrophobic core leucines (LEU136, LEU140) as the source of directional signaling toward the iron‐binding acidic ridge.
Kevser Kübra Kırboğa, Ecir Uğur Küçüksille   +1 more
wiley   +1 more source

Bidirectional crosstalk between the nervous system and the tumour microenvironment: mechanisms, feedback loops and therapeutic opportunities. [PDF]

Front Cell Dev Biol
Kuang G, Qiu Z, Li L, Ji H, Liu Y.
europepmc   +1 more source

Framework for headache management in pediatric patients with stroke and cerebrovascular lesions: A narrative review

Headache: The Journal of Head and Face Pain, EarlyView.
Abstract Objective To present a practical, evidence‐based framework for the management of headache disorders in pediatric patients with prior stroke or underlying cerebral vascular lesions, with particular attention to safety and efficacy of pharmacologic and non‐pharmacologic therapies.
Allison C. Hyland, Samuel J. Belfer, Christine K. Fox, Samantha L. Irwin, Rachel Vassar, Ann Oh, Sruthi Ilangovan, Amy A. Gelfand   +7 more
wiley   +1 more source

Neural regulation of tumor immunity: emerging opportunities to enhance cancer immunotherapy. [PDF]

Exp Mol Med
Chen X, Zou M, Li N, Feng W, Lin P, Lin Y, Zhao X, Cui L.   +7 more
europepmc   +1 more source

The Interactions Between Acetylcholine and T‐Cells and Their Role in the Immune System: A Scoping Review

Immunology, EarlyView.
Activated T‐cells instigate signalling events leading to the activation of transcription factors, which in turn, act on the nucleus to produce cytokines. We postulate that c‐fos is one of these transcription factors which upregulates the choline acetyltransferase gene responsible for synthesising acetylcholine (ACh).
Jarita Lay, Nicholas Manolios
wiley   +1 more source

Pathophysiology and Perioperative Considerations for Heart Failure Patients. [PDF]

Life (Basel)
Crowley S, Tawfik GA, Villa R, Larson C, Yeung I, Bergese SD.   +5 more
europepmc   +1 more source

POTENTIATION OF β-ADRENERGIC RECEPTOR TO MUSK

Japanese Journal of Pharmacology, 1966
KIMURA, MASAYASU, WAKI, ISAMI
openaire   +3 more sources