Results 21 to 30 of about 261,029 (355)

In Vivo Stimulation of α- and β-Adrenoceptors in Mice Differentially Alters Small RNA Content of Circulating Extracellular Vesicles

open access: yesCells, 2021
When myocardial function is compromised as in heart failure (HF), there is activation of the sympathetic nervous system with elevated circulating catecholamine levels.
Jin-Sook Kwon   +3 more
doaj   +1 more source

Genetic Polymorphism of beta1-adrenergic Receptors and the Effect on the Clinical Efficacy of beta-adrenoblockers

open access: yesРациональная фармакотерапия в кардиологии, 2021
Beta-adrenergic blockers are a valuable class of cardiovascular drugs and are widely used in the treatment of arterial hypertension (AH), coronary heart disease, chronic heart failure (CHF), cardiac arrhythmias, significantly improving the prognosis of ...
V. N. Larina, M. V. Leonova
doaj   +1 more source

Both Ligand- and Cell-Specific Parameters Control Ligand Agonism in a Kinetic Model of G Protein–Coupled Receptor Signaling [PDF]

open access: yes, 2007
G protein–coupled receptors (GPCRs) exist in multiple dynamic states (e.g., ligand-bound, inactive, G protein–coupled) that influence G protein activation and ultimately response generation. In quantitative models of GPCR signaling that incorporate these
Kinzer-Ursem, Tamara L.   +1 more
core   +3 more sources

Inhibition of the lipolytic action of beta-adrenergic agonists in human adipocytes by alpha-adrenergic agonists.

open access: yesJournal of Lipid Research, 1981
The aim of this study was to define the role of the alpha-adrenergic receptor in the regulation of lipolysis by human adipocytes. Glycerol production by isolated human adipocytes was stimulated by the pure beta-adrenergic agonist isoproterenol in a dose ...
E E Wright, E R Simpson
doaj   +1 more source

Molecular biology of amitraz resistance in cattle ticks of the genus Rhipicephalus [PDF]

open access: yes, 2018
Amitraz is an important product for the control of cattle ticks around the world. In comparison with other products for the control of ticks, it is quite affordable and it has a rapid knock-down effect.
Berry, Christina M.   +5 more
core   +1 more source

Beta-adrenergic receptors in cancer: therapeutic implications.

open access: yesOncology Research, 2010
The beta-adrenergic receptors transduce catecholamine signals to the G protein, which through a cascade of chemical reactions in cells generates highly specific parallel signals.
M. Pérez‐Sayáns   +5 more
semanticscholar   +1 more source

Expression of inwardly rectifying potassium channels (GIRKs) and beta-adrenergic regulation of breast cancer cell lines

open access: yesBMC Cancer, 2004
Background Previous research has indicated that at various organ sites there is a subset of adenocarcinomas that is regulated by beta-adrenergic and arachidonic acid-mediated signal transduction pathways.
Cakir Yavuz   +3 more
doaj   +1 more source

Neural regulation of cancer: from mechanobiology to inflammation. [PDF]

open access: yes, 2016
Despite recent progress in cancer research, the exact nature of malignant transformation and its progression is still not fully understood. Particularly metastasis, which accounts for most cancer death, is a very complex process, and new treatment ...
Kim, Tae-Hyung   +2 more
core   +2 more sources

Pheochromocytoma – clinical manifestations, diagnosis and current perioperative management [PDF]

open access: yes, 2019
Pheochromocytoma is a neuroendocrine tumor characterized by the excessive production of catecholamines (epinephrine, norepinephrine, and dopamine). The diagnosis is suspected due to hypertensive paroxysms, associated with vegetative phenomena, due to the
Bratu, Ovidiu G   +6 more
core   +2 more sources

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